Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Facial Dermatoses D005148 7 associated lipids
Bacteriuria D001437 7 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Liver Abscess D008100 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Foreign Bodies D005547 5 associated lipids
Clostridium Infections D003015 5 associated lipids
Pyoderma D011711 5 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Gotoh Y et al. Chemical transformation of tylosin derivatives into neutral macrolides having a 3'-methoxyl group. 1998 Carbohydr. Res. pmid:9720235
Synek M et al. [Immunologic aspects of macrolide antibiotics]. 1989 Cas. Lek. Cesk. pmid:2731206
Bébrová E et al. [Immunologic reactivity of tylosin and erythromycin]. 1989 Cesk Epidemiol Mikrobiol Imunol pmid:2790978
Butler AR et al. Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiae. 1999 Chem. Biol. pmid:10322123
Starosta AL et al. Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition. 2010 Chem. Biol. pmid:20534348
Bate N et al. Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae. 1999 Chem. Biol. pmid:10467127
Stratigopoulos G and Cundliffe E Expression analysis of the tylosin-biosynthetic gene cluster: pivotal regulatory role of the tylQ product. 2002 Chem. Biol. pmid:11841940
De Liguoro M et al. Use of oxytetracycline and tylosin in intensive calf farming: evaluation of transfer to manure and soil. 2003 Chemosphere pmid:12729703
Chen C et al. Effect of composting and soil type on dissipation of veterinary antibiotics in land-applied manures. 2018 Chemosphere pmid:29306199
Kolz AC et al. Sorption of tylosin onto swine manure. 2005 Chemosphere pmid:15914248
Hossain A et al. Occurrence, distribution, ecological and resistance risks of antibiotics in surface water of finfish and shellfish aquaculture in Bangladesh. 2017 Chemosphere pmid:28888121
Blackwell PA et al. The dissipation and transport of veterinary antibiotics in a sandy loam soil. 2007 Chemosphere pmid:17204303
Guo X et al. Sorption properties of tylosin on four different microplastics. 2018 Chemosphere pmid:29933160
Stromer BS et al. Tylosin sorption to diatomaceous earth described by Langmuir isotherm and Freundlich isotherm models. 2018 Chemosphere pmid:29874766
Mitchell SM et al. Hydrolysis of amphenicol and macrolide antibiotics: Chloramphenicol, florfenicol, spiramycin, and tylosin. 2015 Chemosphere pmid:25618189
Ali M et al. Effect of redox potential and pH status on degradation and adsorption behavior of tylosin in dairy lagoon sediment suspension. 2013 Chemosphere pmid:23352520
Zhang Q et al. Sorption of tylosin on clay minerals. 2013 Chemosphere pmid:24007614
Halling-Sørensen B Algal toxicity of antibacterial agents used in intensive farming. 2000 Chemosphere pmid:10705551
van der Grinten E et al. Comparing the sensitivity of algal, cyanobacterial and bacterial bioassays to different groups of antibiotics. 2010 Chemosphere pmid:20430416
Loke ML et al. Determination of the distribution coefficient (log Kd) of oxytetracycline, tylosin A, olaquindox and metronidazole in manure. 2002 Chemosphere pmid:12146624