| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lymphadenitis | D008199 | 8 associated lipids |
| Mycoplasma Infections | D009175 | 13 associated lipids |
| Mycoplasmatales Infections | D009180 | 6 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Pasteurella Infections | D010326 | 8 associated lipids |
| Pneumonia, Mycoplasma | D011019 | 6 associated lipids |
| Poultry Diseases | D011201 | 21 associated lipids |
| Pyoderma | D011711 | 5 associated lipids |
| Pasteurellosis, Pneumonic | D012766 | 3 associated lipids |
| Staphylococcal Skin Infections | D013207 | 9 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- J. Antimicrob. Chemother. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Onan LJ and LaPara TM | Tylosin-resistant bacteria cultivated from agricultural soil. | 2003 | FEMS Microbiol. Lett. | pmid:12644222 |
| Von Essen S et al. | Unintentional human exposure to tilmicosin (Micotil 300). | 2003 | J. Toxicol. Clin. Toxicol. | pmid:12807303 |
| Del Vecchio F et al. | Active-site residue, domain and module swaps in modular polyketide synthases. | 2003 | J. Ind. Microbiol. Biotechnol. | pmid:12811585 |
| Anderegg TR and Jones RN | Initial disk diffusion quality control guidelines for tylosin tested against Staphylococcus aureus ATCC 25923 and Streptococcus pneumoniae ATCC 49619. | 2003 | Int. J. Antimicrob. Agents | pmid:12791478 |
| Tarabla H and Canavesio V | Prevalence of intramammary infections by major pathogens at parturition in dairy cows after intramuscular antibiotic therapy at drying-off: a preliminary report. | 2003 | J. Dairy Res. | pmid:12800878 |
| Loria GR et al. | In vitro susceptibilities of field isolates of Mycoplasma agalactiae to oxytetracycline, tylosin, enrofloxacin, spiramycin and lincomycin-spectinomycin. | 2003 | Res. Vet. Sci. | pmid:12801456 |
| Althaus RL et al. | Detection limits of antimicrobials in ewe milk by delvotest photometric measurements. | 2003 | J. Dairy Sci. | pmid:12647952 |
| Horie M et al. | [Determination of spiramycin and tilmicosin in meat and fish by LC/MS]. | 2003 | Shokuhin Eiseigaku Zasshi | pmid:12968469 |
| Marks SL and Kather EJ | Antimicrobial susceptibilities of canine Clostridium difficile and Clostridium perfringens isolates to commonly utilized antimicrobial drugs. | 2003 | Vet. Microbiol. | pmid:12742714 |
| Iveković D et al. | Electrochemical reduction of desmycosin, structure investigation and antibacterial evaluation of the resulting products. | 2003 | Eur J Pharm Sci | pmid:12694884 |
| Rodriguez E et al. | Rapid engineering of polyketide overproduction by gene transfer to industrially optimized strains. | 2003 | J. Ind. Microbiol. Biotechnol. | pmid:12698320 |
| Moubareck C et al. | Multiple antibiotic resistance gene transfer from animal to human enterococci in the digestive tract of gnotobiotic mice. | 2003 | Antimicrob. Agents Chemother. | pmid:12937011 |
| Van Lunen TA | Growth performance of pigs fed diets with and without tylosin phosphate supplementation and reared in a biosecure all-in all-out housing system. | 2003 | Can. Vet. J. | pmid:12892287 |
| Teeter JS and Meyerhoff RD | Aerobic degradation of tylosin in cattle, chicken, and swine excreta. | 2003 | Environ. Res. | pmid:12865047 |
| Creemer LC et al. | Facile synthesis of tilmicosin and tylosin related haptens for use as protein conjugates. | 2003 | J. Antibiot. | pmid:12870814 |
| Jost BH et al. | Tylosin resistance in Arcanobacterium pyogenes is encoded by an erm X determinant. | 2003 | Antimicrob. Agents Chemother. | pmid:14576111 |
| Lee HJ and Jin HJ | Renaturation of recombinant ErmSF and its refolding behavior. | 2003 | Mol. Cells | pmid:14651260 |
| Prapasarakul N et al. | In vitro susceptibility and a new point mutation associated with tylosin-resistance in Japanese canine intestinal spirochetes. | 2003 | J. Vet. Med. Sci. | pmid:14709813 |
| German AJ et al. | Comparison of direct and indirect tests for small intestinal bacterial overgrowth and antibiotic-responsive diarrhea in dogs. | 2003 Jan-Feb | J. Vet. Intern. Med. | pmid:12564725 |
| Stratigopoulos G et al. | Positive control of tylosin biosynthesis: pivotal role of TylR. | 2004 | Mol. Microbiol. | pmid:15554972 |
| Taniguchi K et al. | The role of histidine residues conserved in the putative ATP-binding region of macrolide 2'-phosphotransferase II. | 2004 | FEMS Microbiol. Lett. | pmid:15033229 |
| Paradis MA et al. | Efficacy of tilmicosin in the control of experimentally induced Actinobacillus pleuropneumoniae infection in swine. | 2004 | Can. J. Vet. Res. | pmid:14979429 |
| Jost BH et al. | A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes. | 2004 | Antimicrob. Agents Chemother. | pmid:14982756 |
| Douthwaite S et al. | The tylosin-resistance methyltransferase RlmA(II) (TlrB) modifies the N-1 position of 23S rRNA nucleotide G748. | 2004 | J. Mol. Biol. | pmid:15046978 |
| Elitok B and Elitok OM | Clinical efficacy of carprofen as an adjunct to the antibacterial treatment of bovine respiratory disease. | 2004 | J. Vet. Pharmacol. Ther. | pmid:15500569 |
| Clark C et al. | A preliminary investigation of the disposition of tilmicosin residues in elk tissues and serum. | 2004 | J. Vet. Pharmacol. Ther. | pmid:15500580 |
| Civitareale C et al. | Identification and quantification method of spiramycin and tylosin in feedingstuffs with HPLC-UV/DAD at 1 ppm level. | 2004 | J Pharm Biomed Anal | pmid:15496324 |
| Novotny GW et al. | Ketolide antimicrobial activity persists after disruption of interactions with domain II of 23S rRNA. | 2004 | Antimicrob. Agents Chemother. | pmid:15388419 |
| Montesissa C et al. | Metabolism of tilmicosin by rabbit liver microsomes and hepatocytes. | 2004 | Vet. J. | pmid:14623156 |
| Mutak S et al. | Semisynthetic macrolide antibacterials derived from tylosin. Synthesis and structure-activity relationships of novel desmycosin analogues. | 2004 | J. Med. Chem. | pmid:14711312 |
| Phan LT et al. | Synthesis and antibacterial activity of a novel class of 4'-substituted 16-membered ring macrolides derived from tylosin. | 2004 | J. Med. Chem. | pmid:15163176 |
| Brumbaugh GW et al. | Susceptibility of Mycobacterium avium sbsp paratuberculosis to monensin sodium or tilmicosin phosphate in vitro and resulting infectivity in a murine model. | 2004 | Can. J. Vet. Res. | pmid:15352541 |
| Poole TL et al. | Competitive exclusion of a glycopeptide-resistant Enterococcus faecium in the presence of vancomycin but not equivalent concentrations of tylosin or gentamicin. | 2004 | Poult. Sci. | pmid:15285499 |
| Lum AM et al. | Reverse engineering of industrial pharmaceutical-producing actinomycete strains using DNA microarrays. | 2004 | Metab. Eng. | pmid:15256208 |
| Jackson CR et al. | Effects of tylosin use on erythromycin resistance in enterococci isolated from swine. | 2004 | Appl. Environ. Microbiol. | pmid:15240302 |
| Lawrence K | Change to user warning for Micotil. | 2004 | Vet. Rec. | pmid:15200081 |
| Kay P et al. | Fate of veterinary antibiotics in a macroporous tile drained clay soil. | 2004 | Environ. Toxicol. Chem. | pmid:15180364 |
| Pettis JS et al. | Larval Apis mellifera L. (Hymenoptera: Apidae) mortality after topical application of antibiotics and dusts. | 2004 | J. Econ. Entomol. | pmid:15154433 |
| Chirase NK et al. | Effect of simulated ambient particulate matter exposure on performance, rectal temperature, and leukocytosis of young Spanish goats with or without tilmicosin phosphate. | 2004 | J. Anim. Sci. | pmid:15080345 |
| Fajt VR et al. | Effect of danofloxacin and tilmicosin on body temperatures of beef calves with pneumonia experimentally induced by inoculation with Mannheimia haemolytica. | 2004 | Am. J. Vet. Res. | pmid:15141881 |
| Van Poucke C et al. | Tylosin detection in animal feed by liquid chromatography-tandem mass spectrometry with enzymatic hydrolysis of the tylosin urea adduct. | 2004 | J. Agric. Food Chem. | pmid:15137817 |
| Cusack PM | Effect of mass medication with antibiotics at feedlot entry on the health and growth rate of cattle destined for the Australian domestic market. | 2004 | Aust. Vet. J. | pmid:15088981 |
| Zhang Y et al. | Residue depletion of tilmicosin in chicken tissues. | 2004 | J. Agric. Food Chem. | pmid:15113165 |
| Wang J | Determination of five macrolide antibiotic residues in honey by LC-ESI-MS and LC-ESI-MS/MS. | 2004 | J. Agric. Food Chem. | pmid:14733491 |
| Moretto A et al. | Slow release of two antibiotics of veterinary interest from PVA hydrogels. | 2004 | Farmaco | pmid:14751309 |
| Ammida NH et al. | Analysis of erythromycin and tylosin in bovine muscle using disposable screen printed electrodes. | 2004 | Analyst | pmid:14737577 |
| Karlsson M et al. | Further characterization of porcine Brachyspira hyodysenteriae isolates with decreased susceptibility to tiamulin. | 2004 | J. Med. Microbiol. | pmid:15017283 |
| Rowan TG et al. | Efficacy of danofloxacin in the treatment of respiratory disease in European cattle. | 2004 | Vet. Rec. | pmid:15160844 |
| Mathers JJ et al. | Inhibition of resistance plasmid transfer in Escherichia coli by ionophores, chlortetracycline, bacitracin, and ionophore/antimicrobial combinations. | 2004 Apr-Jun | Avian Dis. | pmid:15283418 |
| Yildiz S et al. | Tylosin does not affect GnRH-induced LH secretion in rams. | 2004 Jan-Feb | Reprod. Toxicol. | pmid:15013072 |