Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Lymphadenitis D008199 8 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Occupational Diseases D009784 42 associated lipids
Pasteurella Infections D010326 8 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Poultry Diseases D011201 21 associated lipids
Pyoderma D011711 5 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Scott BA et al. Efficacy of tylosin tartrate on canine Staphylococcus intermedius isolates in vitro. 2010 Vet. Ther. pmid:20960412
Gyémánt N et al. In vitro and in vivo multidrug resistance reversal activity by a Betti-base derivative of tylosin. 2010 Br. J. Cancer pmid:20551959
Starosta AL et al. Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition. 2010 Chem. Biol. pmid:20534348
Paraud C et al. Evaluation of oral tilmicosin efficacy against severe cryptosporidiosis in neonatal kids under field conditions. 2010 Vet. Parasitol. pmid:20149542
Er A et al. Effects of tylosin on serum cytokine levels in healthy and lipopolysaccharide-treated mice. 2010 Acta Vet. Hung. pmid:20159741
Barbour EK et al. Impact of synergism of calcium phosphomycin/tylosin tartarate supplements on the performance of broilers in the Lebanon. 2010 Jan-Mar Vet. Ital. pmid:20391366
Sumbatian NV et al. [Amino acid and peptide derivatives of the tylosin family of macrolide antibiotics modified at the aldehyde group]. 2010 Mar-Apr Bioorg. Khim. pmid:20531486
Reynaldi FJ et al. [Binding of tylosin, tilmicosin and oxytetracycline to proteins from honeybees, larvae and beehive products]. 2010 Oct-Dec Rev. Argent. Microbiol. pmid:21229198
Shimada T et al. Effects of the antimicrobial tylosin on the microbial community structure of an anaerobic sequencing batch reactor. 2011 Biotechnol. Bioeng. pmid:20830676
Stead SL et al. Development and validation of a potentiometric biosensor assay for tylosin with demonstrated applicability for the detection of two other antimicrobial growth-promoter compounds in feedstuffs. 2011 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:21574083
Kucerova Z et al. Antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolates from clinical outbreaks of porcine respiratory diseases. 2011 Vet. Microbiol. pmid:21316872
Guan S et al. Immunosuppressive activity of tilmicosin on the immune responses in mice. 2011 Immunopharmacol Immunotoxicol pmid:20718577
Lombardi KR et al. Pharmacokinetics of tilmicosin in beef cattle following intravenous and subcutaneous administration. 2011 J. Vet. Pharmacol. Ther. pmid:21323676
Xie S et al. Acute toxicity study of tilmicosin-loaded hydrogenated castor oil-solid lipid nanoparticles. 2011 Part Fibre Toxicol pmid:22098626
Danzeisen JL et al. Modulations of the chicken cecal microbiome and metagenome in response to anticoccidial and growth promoter treatment. 2011 PLoS ONE pmid:22114729
Forrester CA et al. Mycoplasma gallisepticum in pheasants and the efficacy of tylvalosin to treat the disease. 2011 Avian Pathol. pmid:22107092
Bohm DA et al. Preparation and characterisation of in-house reference material of tylosin in honey and results of a proficiency test. 2011 Anal. Chim. Acta pmid:21742117
Dinh QT et al. Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. 2011 Talanta pmid:21807177
Gerchman I et al. Characterization of in vivo-acquired resistance to macrolides of Mycoplasma gallisepticum strains isolated from poultry. 2011 Vet. Res. pmid:21810258
Lust EB et al. Human health hazards of veterinary medications: information for emergency departments. 2011 J Emerg Med pmid:20045604