Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Poultry Diseases D011201 21 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Pasteurella Infections D010326 8 associated lipids
Occupational Diseases D009784 42 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Lymphadenitis D008199 8 associated lipids
Liver Abscess D008100 6 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Hyperplasia D006965 34 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Scott DW et al. Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. 1996 Can. Vet. J. pmid:8896878
Katoh T et al. Effect of a combination of antimicrobial agents for the treatment of respiratory disease in cattle. 1996 J. Vet. Med. Sci. pmid:8877980
Katoh T et al. The fractional inhibitory concentration index of antimicrobial agents for bacteria and Mycoplasma isolated from the nasal swabs of cattle with respiratory diseases. 1996 J. Vet. Med. Sci. pmid:8877979
Harvey RG Tylosin in the treatment of canine superficial pyoderma. 1996 Vet. Rec. pmid:8873399
Kobayashi H et al. Macrolide susceptibility of Mycoplasma hyorhinis isolated from piglets. 1996 Antimicrob. Agents Chemother. pmid:8849222
Shryock TR et al. Minimum inhibitory concentration breakpoints and disk diffusion inhibitory zone interpretive criteria for tilmicosin susceptibility testing against Pasteurella spp. associated with bovine respiratory disease. 1996 J. Vet. Diagn. Invest. pmid:8844577
McKay SG et al. Use of tilmicosin for treatment of pasteurellosis in rabbits. 1996 Am. J. Vet. Res. pmid:8836371
Peng CY et al. Laboratory and field studies on the effects of the antibiotic tylosin on honey bee Apis mellifera L. (Hymenoptera: Apidae) development and prevention of American foulbrood disease. 1996 J. Invertebr. Pathol. pmid:8812572
Main BW et al. Cardiovascular effects of the macrolide antibiotic tilmicosin, administered alone and in combination with propranolol or dobutamine, in conscious unrestrained dogs. 1996 J. Vet. Pharmacol. Ther. pmid:8803881
Jordan FT and Horrocks BK The minimum inhibitory concentration of tilmicosin and tylosin for mycoplasma gallisepticum and Mycoplasma synoviae and a comparison of their efficacy in the control of Mycoplasma gallisepticum infection in broiler chicks. 1996 Apr-Jun Avian Dis. pmid:8790882
Blackall PJ et al. In-vitro antibacterial properties of tilmicosin against Australian isolates of Pasteurella multocida and Actinobacillus pleuropneumoniae from pigs. 1995 Aust. Vet. J. pmid:8787526
Wittum TE et al. Haptoglobin response to clinical respiratory tract disease in feedlot cattle. 1996 Am. J. Vet. Res. pmid:8723875
Musser J et al. Comparison of tilmicosin with long-acting oxytetracycline for treatment of respiratory tract disease in calves. 1996 J. Am. Vet. Med. Assoc. pmid:8682696
Molnár L Sensitivity of strains of Serpulina hyodysenteriae isolated in Hungary to chemotherapeutic drugs. 1996 Vet. Rec. pmid:8677605
Scott PR et al. Use of tilmicosin in a severe outbreak of respiratory disease in weaned beef calves. 1996 Aust. Vet. J. pmid:8660201
Tuomi ML and Räsänen L Contact allergy to tylosin and cobalt in a pig-farmer. 1995 Contact Derm. pmid:8654098
Arisawa A et al. Direct fermentative production of acyltylosins by genetically-engineered strains of Streptomyces fradiae. 1996 J. Antibiot. pmid:8641997
Ngoh MA Determination of tilmicosin in bovine milk by liquid chromatography with ultraviolet detection. 1996 May-Jun J AOAC Int pmid:8634534
Moore GM et al. Clinical field trials with tilmicosin phosphate in feed for the control of naturally acquired pneumonia caused by Actinobacillus pleuropneumoniae and Pasteurella multocida in swine. 1996 Am. J. Vet. Res. pmid:8633813
Moore GM et al. Efficacy dose determination study of tilmicosin phosphate in feed for control of pneumonia caused by Actinobacillus pleuropneumoniae in swine. 1996 Am. J. Vet. Res. pmid:8633812
Solenberg PJ et al. Transposition mutagenesis in Streptomyces fradiae: identification of a neutral site for the stable insertion of DNA by transposon exchange. 1996 Gene pmid:8626067
Day FG The value of tilmicosin in production medicine. 1996 J. Am. Vet. Med. Assoc. pmid:8617615
Brown SA et al. Characterization of plasma and lung concentrations after ceftiofur sodium and tilmicosin phosphate administered subcutaneously to mice. 1995 J. Vet. Pharmacol. Ther. pmid:8587160
Ziv G et al. Tilmicosin antibacterial activity and pharmacokinetics in cows. 1995 J. Vet. Pharmacol. Ther. pmid:8587151
Ziv G et al. Disposition kinetics of tylosin tartrate administered intravenously and intramuscularly to normal and water-deprived camels. 1995 J. Vet. Pharmacol. Ther. pmid:8583543
Paesen J et al. Study of the stability of tylosin A in aqueous solutions. 1995 J Pharm Biomed Anal pmid:8573642
Lee SH and Lee KJ Threonine dehydratases in different strains of Streptomyces fradiae. 1995 J. Biotechnol. pmid:8562022
Scott PR Efficacy of strategic tilmicosin injection during an outbreak of respiratory disease in housed beef calves. 1995 Sep-Oct Br. Vet. J. pmid:8556318
Kiehl DE and Kennington AS Analysis of tilmicosin in swine liver extracts by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry. 1995 Rapid Commun. Mass Spectrom. pmid:8527821
Kirchgessner M et al. [Effect of avilamycin and tylosin on the metabolizable energy in growing and finishing pigs]. 1995 Arch Tierernahr pmid:8526732
Danielson ND et al. Simple methods for the qualitative identification and quantitative determination of macrolide antibiotics. 1993 J Pharm Biomed Anal pmid:8504183
Lee SH and Lee KJ Aspartate aminotransferase and tylosin biosynthesis in Streptomyces fradiae. 1993 Appl. Environ. Microbiol. pmid:8481008
Jordan WH et al. A review of the toxicology of the antibiotic MICOTIL 300. 1993 Vet Hum Toxicol pmid:8470360
Roets E et al. Quantitative analysis of tylosin by column liquid chromatography. 1993 J. Chromatogr. pmid:8445000
Cester CC et al. Effect of stage of oestrous cycle on tylosin disposition in genital tract secretions of cows. 1993 Res. Vet. Sci. pmid:8434145
Binder S et al. [The effectiveness of tilmicosin in respiratory diseases of swine]. 1993 Berl. Munch. Tierarztl. Wochenschr. pmid:8431202
Morck DW et al. Prophylactic efficacy of tilmicosin for bovine respiratory tract disease. 1993 J. Am. Vet. Med. Assoc. pmid:8428833
Kageyama S et al. Synthesis of 3-deoxy-3,4-didehydro derivatives of 5-O-mycaminosyltylonolide, 5-O-(4-deoxymycaminosyl) tylonolide, and desmycosin. 1993 J. Antibiot. pmid:8407589
Tanner AC et al. A comparison of danofloxacin and tylosin in the control of induced Mycoplasma gallisepticum infection in broiler chicks. 1993 Apr-Jun Avian Dis. pmid:8395804
Migaki TT et al. Efficacy of danofloxacin and tylosin in the control of mycoplasmosis in chicks infected with tylosin-susceptible or tylosin-resistant field isolates of Mycoplasma gallisepticum. 1993 Apr-Jun Avian Dis. pmid:8395803
Cooper AC et al. In vitro activity of danofloxacin, tylosin and oxytetracycline against mycoplasmas of veterinary importance. 1993 Res. Vet. Sci. pmid:8393208
Meisel ML et al. Tylosin inhibits the steroidogenesis in mouse Leydig cells "in vitro". 1993 Life Sci. pmid:8390595
Jordan FT et al. A comparison of the efficacy of danofloxacin and tylosin in the control of Mycoplasma gallisepticum infection in broiler chicks. 1993 J. Vet. Pharmacol. Ther. pmid:8386777
Meisel ML et al. Effects of tylosin on the pituitary-gonadal axis in male rats. 1993 Apr-May Pharmacol. Toxicol. pmid:8372057
Huang SL et al. Purification and properties of NADPH-dependent tylosin reductase from Streptomyces fradiae. 1993 J. Biol. Chem. pmid:8360186
Westermarck E et al. Effect of treatment on the jejunal and colonic bacterial flora of dogs with exocrine pancreatic insufficiency. 1993 Pancreas pmid:8302792
Tanner AC et al. Adaptation of the Sensititre broth microdilution technique to antimicrobial susceptibility testing of Mycoplasma hyopneumoniae. 1993 Vet. Microbiol. pmid:8273275
Clary EM et al. Supplemental fat and ionophores in finishing diets: feedlot performance and ruminal digesta kinetics in steers. 1993 J. Anim. Sci. pmid:8270535
Stephens CP et al. In-vitro antibacterial properties of tilmicosin against Australian isolates of Pasteurella multocida and Pasteurella haemolytica from cattle. 1993 Aust. Vet. J. pmid:8257321
Takhirov MT et al. [Determination of tylosin in the water supply using a chromatographic method]. 1993 Gig Sanit pmid:8244081