Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Poultry Diseases D011201 21 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Pasteurella Infections D010326 8 associated lipids
Occupational Diseases D009784 42 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Lymphadenitis D008199 8 associated lipids
Liver Abscess D008100 6 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Hyperplasia D006965 34 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Stone JJ et al. Tylosin and chlortetracycline effects during swine manure digestion: influence of sodium azide. 2010 Bioresour. Technol. pmid:20728345
Granja R et al. Determination of erythromycin and tylosin residues in honey by LC/MS/MS. 2009 May-Jun J AOAC Int pmid:19610392
Sharma R et al. Selected antimicrobial resistance during composting of manure from cattle administered sub-therapeutic antimicrobials. 2009 Mar-Apr J. Environ. Qual. pmid:19202027
Smith GW et al. Elimination kinetics of tilmicosin following intramammary administration in lactating dairy cattle. 2009 J. Am. Vet. Med. Assoc. pmid:19210246
Kouvela EC et al. Distinct mode of interaction of a novel ketolide antibiotic that displays enhanced antimicrobial activity. 2009 Antimicrob. Agents Chemother. pmid:19164155
Baggio A et al. Residues of antibacterial drugs in honey from the Italian market. 2009 Food Addit Contam Part B Surveill pmid:24784967
Chemier JA et al. Trends in microbial synthesis of natural products and biofuels. 2009 Adv. Enzymol. Relat. Areas Mol. Biol. pmid:18990830
Montgomery JL et al. Effects of dietary zilpaterol hydrochloride on feedlot performance and carcass characteristics of beef steers fed with and without monensin and tylosin. 2009 J. Anim. Sci. pmid:18997069
Boles JA et al. Growth implants reduced tenderness of steaks from steers and heifers with different genetic potentials for growth and marbling. 2009 J. Anim. Sci. pmid:18791138
Han C et al. Hydrogenated castor oil nanoparticles as carriers for the subcutaneous administration of tilmicosin: in vitro and in vivo studies. 2009 J. Vet. Pharmacol. Ther. pmid:19290940
Engi H [Perspectives of inhibition of multidrug resistance during cancer chemotherapy, in vitro and in vivo experiments]. 2009 Orv Hetil pmid:19293063
Hoese A et al. Chlortetracycline and tylosin runoff from soils treated with antimicrobial containing manure. 2009 J Environ Sci Health B pmid:19365753
Meyer NF et al. Effect of essential oils, tylosin, and monensin on finishing steer performance, carcass characteristics, liver abscesses, ruminal fermentation, and digestibility. 2009 J. Anim. Sci. pmid:19359504
Christodoulopoulos G Adverse outcome of using tilmicosin in a lamb with multiple ventricular septal defects. 2009 Can. Vet. J. pmid:19337615
Khaliq S et al. Production of tylosin in solid-state fermentation by Streptomyces fradiae NRRL-2702 and its gamma-irradiated mutant (gamma-1). 2009 Lett. Appl. Microbiol. pmid:19780953
Hu D and Coats JR Laboratory evaluation of mobility and sorption for the veterinary antibiotic, tylosin, in agricultural soils. 2009 J Environ Monit pmid:19724833
Khalifeh MS et al. Assessment of humoral and cellular-mediated immune response in chickens treated with tilmicosin, florfenicol, or enrofloxacin at the time of Newcastle disease vaccination. 2009 Poult. Sci. pmid:19762865
Guedes RM et al. Use of tylvalosin-medicated feed to control porcine proliferative enteropathy. 2009 Vet. Rec. pmid:19767637
Fitzgerald J Administration of micotil. 2009 Vet. Rec. pmid:19767643
Stone JJ et al. Effect of antimicrobial compounds tylosin and chlortetracycline during batch anaerobic swine manure digestion. 2009 Water Res. pmid:19695662
Atef M et al. Effect of albendazole administration on pharmacokinetic aspects of tylosin in lactating goats. 2009 Drug Metab Lett pmid:19702546
Hilton GG et al. Effects of feeding zilpaterol hydrochloride with and without monensin and tylosin on carcass cutability and meat palatability of beef steers. 2009 J. Anim. Sci. pmid:19028853
Byrne-Bailey KG et al. Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. 2009 Antimicrob. Agents Chemother. pmid:19064898
Petropoulos AD et al. Time-resolved binding of azithromycin to Escherichia coli ribosomes. 2009 J. Mol. Biol. pmid:19071138
Blackwell PA et al. Effects of agricultural conditions on the leaching behaviour of veterinary antibiotics in soils. 2009 Chemosphere pmid:19128817
Chénier MR and Juteau P Fate of chlortetracycline- and tylosin-resistant bacteria in an aerobic thermophilic sequencing batch reactor treating swine waste. 2009 Microb. Ecol. pmid:19125305
Liu F et al. Effects of six selected antibiotics on plant growth and soil microbial and enzymatic activities. 2009 Environ. Pollut. pmid:19157661
Bodoor K et al. Design and implementation of an ribonucleic acid (RNA) directed fragment library. 2009 J. Med. Chem. pmid:19445516
Hunter RP et al. Letter to the editor. 2009 Br. Poult. Sci. pmid:19904632
Suchodolski JS et al. The effect of the macrolide antibiotic tylosin on microbial diversity in the canine small intestine as demonstrated by massive parallel 16S rRNA gene sequencing. 2009 BMC Microbiol. pmid:19799792
Warner K et al. Control of Ornithobacterium rhinotracheale in poultry. 2009 Vet. Rec. pmid:19946131
Hao H et al. 23S rRNA mutation A2074C conferring high-level macrolide resistance and fitness cost in Campylobacter jejuni. 2009 Microb. Drug Resist. pmid:19857128
Khaliq S et al. Change in colony morphology and kinetics of tylosin production after UV and gamma irradiation mutagenesis of Streptomyces fradiae NRRL-2702. 2009 Microbiol. Res. pmid:17475458
Ramlachan N et al. A comparative study on the effects of tylosin on select bacteria during continuous flow culture of mixed populations of gut microflora derived from a feral and a domestic pig. 2008 Foodborne Pathog. Dis. pmid:18260812
Jacob ME et al. Effects of feeding wet corn distillers grains with solubles with or without monensin and tylosin on the prevalence and antimicrobial susceptibilities of fecal foodborne pathogenic and commensal bacteria in feedlot cattle. 2008 J. Anim. Sci. pmid:18192558
Clark C et al. Pharmacokinetics of tilmicosin in equine tissues and plasma. 2008 J. Vet. Pharmacol. Ther. pmid:18177321
Hu D et al. Identification of tylosin photoreaction products and comparison of ELISA and HPLC methods for their detection in water. 2008 Environ. Sci. Technol. pmid:18497154
Reynaldi FJ et al. Effectiveness of tilmicosin against Paenibacillus larvae, the causal agent of American Foulbrood disease of honeybees. 2008 Vet. Microbiol. pmid:18539412
Mir PS et al. Effects of dietary sunflower seeds and tylosin phosphate on production variables, carcass characteristics, fatty acid composition, and liver abscess incidence in crossbred steers. 2008 J. Anim. Sci. pmid:18567724
Nickell JS et al. Comparison of short-term health and performance effects related to prophylactic administration of tulathromycin versus tilmicosin in long-hauled, highly stressed beef stocker calves. 2008 Vet. Ther. pmid:18597253
Nathues H and grosse Beilage E Diagnosis of Lawsonia intracellularis infection in pigs after vaccination or antimicrobial treatment. 2008 DTW. Dtsch. Tierarztl. Wochenschr. pmid:19024547
Weber TE and Kerr BJ Effect of sodium butyrate on growth performance and response to lipopolysaccharide in weanling pigs. 2008 J. Anim. Sci. pmid:17998428
Demoling LA and Bååth E No long-term persistence of bacterial pollution-induced community tolerance in tylosin-polluted soil. 2008 Environ. Sci. Technol. pmid:18853809
Castonguay R et al. Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase. 2008 J. Am. Chem. Soc. pmid:18693734
Akhter S et al. Effect of antibiotics in extender on bacterial and spermatozoal quality of cooled buffalo (Bubalus bubalis) bull semen. 2008 Reprod. Domest. Anim. pmid:18042206
Bailey M et al. Induction of erm(C) expression by noninducing antibiotics. 2008 Antimicrob. Agents Chemother. pmid:18086834
Diagnosis | pasteurellosis. 2008 Lab Anim (NY) pmid:18094697
Wagner BA et al. Effect of antimicrobial dosage regimen on Salmonella and Escherichia coli isolates from feeder swine. 2008 Appl. Environ. Microbiol. pmid:18223115
Kim MH et al. Comparative pharmacokinetics of tylosin or florfenicol after a single intramuscular administration at two different doses of tylosin-florfenicol combination in pigs. 2008 J. Vet. Med. Sci. pmid:18250580
Angenent LT et al. Effect of the presence of the antimicrobial tylosin in swine waste on anaerobic treatment. 2008 Water Res. pmid:18258277