Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Poultry Diseases D011201 21 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Pasteurella Infections D010326 8 associated lipids
Occupational Diseases D009784 42 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Lymphadenitis D008199 8 associated lipids
Liver Abscess D008100 6 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Hyperplasia D006965 34 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Whitehead TR et al. Savagea faecisuis gen. nov., sp. nov., a tylosin- and tetracycline-resistant bacterium isolated from a swine-manure storage pit. 2015 Antonie Van Leeuwenhoek pmid:25980832
Li Q et al. Co-addition of manure increases the dissipation rates of tylosin A and the numbers of resistance genes in laboratory incubation experiments. 2015 Sci. Total Environ. pmid:25958362
Kiyoshima K et al. Structure-activity relationship studies on 4''-O-acyltylosin derivatives: significance of their 23-O-mycinosyl and 4''-O-acyl moieties in antimicrobial activity against macrolide-resistant microbes. 1989 J. Antibiot. pmid:2584151
Sura S et al. Transport of three veterinary antimicrobials from feedlot pens via simulated rainfall runoff. 2015 Sci. Total Environ. pmid:25839178
Le T et al. A quantum dot-based immunoassay for screening of tylosin and tilmicosin in edible animal tissues. 2015 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:25822697
Krokidis M et al. The slow dissociation rate of K-1602 contributes to the enhanced inhibitory activity of this novel alkyl-aryl-bearing fluoroketolide. 2016 J Enzyme Inhib Med Chem pmid:25807301
Amachawadi RG et al. Effects of in-feed copper and tylosin supplementations on copper and antimicrobial resistance in faecal enterococci of feedlot cattle. 2015 J. Appl. Microbiol. pmid:25739516
Lysnyansky I et al. Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. 2015 Microb. Drug Resist. pmid:25734368
Luo H et al. Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. 2015 Avian Pathol. pmid:25690020
Yahiaoui I et al. Removal of a mixture tetracycline-tylosin from water based on anodic oxidation on a glassy carbon electrode coupled to activated sludge. Environ Technol pmid:25650749
Mitchell SM et al. Hydrolysis of amphenicol and macrolide antibiotics: Chloramphenicol, florfenicol, spiramycin, and tylosin. 2015 Chemosphere pmid:25618189
Li Y et al. Effects of Cu exposure on enzyme activities and selection for microbial tolerances during swine-manure composting. 2015 J. Hazard. Mater. pmid:25464290
Abdel-Daim MM et al. Synergistic protective role of mirazid (Commiphora molmol) and ascorbic acid against tilmicosin-induced cardiotoxicity in mice. 2015 Can. J. Physiol. Pharmacol. pmid:25429612
Matsushima P et al. Transduction and transformation of plasmid DNA in Streptomyces fradiae strains that express different levels of restriction. 1989 J. Bacteriol. pmid:2542216
Dieste-Pérez L et al. Studies on a suitable antibiotic therapy for treating swine brucellosis. 2015 J. Vet. Pharmacol. Ther. pmid:25413993
Zhu H et al. Immobilization of Streptomyces thermotolerans 11432 on polyurethane foam to improve production of acetylisovaleryltylosin. 2015 J. Ind. Microbiol. Biotechnol. pmid:25413211
Maxwell CL et al. Effects of beef production system on animal performance and carcass characteristics. 2014 J. Anim. Sci. pmid:25403195
VoeÄ­kova TA et al. [Bion-M1. Biological activities of microorganisms under the conditions of a 30-day space flight]. 2014 Aviakosm Ekolog Med pmid:25365877
Tennant TC et al. Comparison of tulathromycin and tilmicosin on the prevalence and severity of bovine respiratory disease in feedlot cattle in association with feedlot performance, carcass characteristics, and economic factors. 2014 J. Anim. Sci. pmid:25349362
Holman DB and Chénier MR Temporal changes and the effect of subtherapeutic concentrations of antibiotics in the gut microbiota of swine. 2014 FEMS Microbiol. Ecol. pmid:25187398
Tavío MM et al. In vitro activity of tylvalosin against Spanish field strains of Mycoplasma hyopneumoniae. 2014 Vet. Rec. pmid:25185108
Avci T and Elmas M Milk and blood pharmacokinetics of tylosin and tilmicosin following parenteral administrations to cows. 2014 ScientificWorldJournal pmid:25177733
Usui M et al. Selection of macrolide-resistant Campylobacter in pigs treated with macrolides. 2014 Vet. Rec. pmid:25163817
Kilpinen S et al. Efficacy of two low-dose oral tylosin regimens in controlling the relapse of diarrhea in dogs with tylosin-responsive diarrhea: a prospective, single-blinded, two-arm parallel, clinical field trial. 2014 Acta Vet. Scand. pmid:25096196
Solliec M et al. Analysis of trimethoprim, lincomycin, sulfadoxin and tylosin in swine manure using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry. 2014 Talanta pmid:25059125
Fujiwara T et al. 19-Deformyl-4'-deoxydesmycosin (TMC-016): synthesis and biological properties of a unique 16-membered macrolide antibiotic. 1989 J. Antibiot. pmid:2500413
Chen X et al. Preparation and evaluation of tilmicosin-loaded hydrogenated castor oil nanoparticle suspensions of different particle sizes. 2014 Int J Nanomedicine pmid:24920902
Sehati N et al. Extraction and preconcentration of tylosin from milk samples through functionalized TiOâ‚‚ nanoparticles reinforced with a hollow fiber membrane as a novel solid/liquid-phase microextraction technique. 2014 J Sep Sci pmid:24890459
Muñoz R et al. Withdrawal times of oxytetracycline and tylosin in eggs of laying hens after oral administration. 2014 J. Food Prot. pmid:24853528
Zhao Z et al. Tylvalosin exhibits anti-inflammatory property and attenuates acute lung injury in different models possibly through suppression of NF-κB activation. 2014 Biochem. Pharmacol. pmid:24792436
Baggio A et al. Residues of antibacterial drugs in honey from the Italian market. 2009 Food Addit Contam Part B Surveill pmid:24784967
Kim HB et al. Effects of tylosin administration on C-reactive protein concentration and carriage of Salmonella enterica in pigs. 2014 Am. J. Vet. Res. pmid:24762018
Ferrag-Siagh F et al. Electro-Fenton pretreatment for the improvement of tylosin biodegradability. 2014 Environ Sci Pollut Res Int pmid:24705893
Beck P et al. Additive effects of growth promoting technologies on performance of grazing steers and economics of the wheat pasture enterprise. 2014 J. Anim. Sci. pmid:24492552
Marosevic D et al. In vivo spread of macrolide-lincosamide-streptogramin B (MLSB) resistance--a model study in chickens. 2014 Vet. Microbiol. pmid:24467930
Entorf M et al. Tylosin susceptibility of Staphylococci from bovine mastitis. 2014 Vet. Microbiol. pmid:24461550
Lerner U et al. Acquired resistance to the 16-membered macrolides tylosin and tilmicosin by Mycoplasma bovis. 2014 Vet. Microbiol. pmid:24393633
Srinivasan P et al. Sorption of selected veterinary antibiotics onto dairy farming soils of contrasting nature. 2014 Sci. Total Environ. pmid:24326064
Ji LW et al. Comparative pharmacokinetics and bioavailability of tylosin tartrate and tylosin phosphate after a single oral and i.v. administration in chickens. 2014 J. Vet. Pharmacol. Ther. pmid:24325541
Khaliq S et al. Characterization of mutations in regulatory genes of Tyl cluster leading to overexpression of tylosin in mutant γ-1 of Streptomyces fradiae NRRL-2702. 2014 Appl. Microbiol. Biotechnol. pmid:24270892
Kawai K et al. Antimicrobial susceptibilities of Mycoplasma isolated from bovine mastitis in Japan. 2014 Anim. Sci. J. pmid:24261609
Amrine DE et al. Pulmonary lesions and clinical disease response to Mannheimia haemolytica challenge 10 days following administration of tildipirosin or tulathromycin. 2014 J. Anim. Sci. pmid:24243906
Pei Z et al. Effects of copper and aluminum on the adsorption of sulfathiazole and tylosin on peat and soil. 2014 Environ. Pollut. pmid:24201036
Guo X et al. The influences of pH and ionic strength on the sorption of tylosin on goethite. 2014 Environ Sci Pollut Res Int pmid:24197966
Pilcher CM et al. Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. 2013 J. Anim. Sci. pmid:24126274
Mitchell SM et al. The effects of the antibiotics ampicillin, florfenicol, sulfamethazine, and tylosin on biogas production and their degradation efficiency during anaerobic digestion. 2013 Bioresour. Technol. pmid:24113548
Shishkina A et al. Conjugates of amino acids and peptides with 5-o-mycaminosyltylonolide and their interaction with the ribosomal exit tunnel. 2013 Bioconjug. Chem. pmid:24090034
Stackhouse-Lawson KR et al. Growth promoting technologies reduce greenhouse gas, alcohol, and ammonia emissions from feedlot cattle. 2013 J. Anim. Sci. pmid:24085413
Kolanović BS et al. Tylosin content in meat and honey samples over a two-year period in Croatia. 2014 J Immunoassay Immunochem pmid:24063615
Corns SM et al. Development of antibiotic regimens using graph based evolutionary algorithms. 2013 BioSystems pmid:24051263