Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Poultry Diseases D011201 21 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Pasteurella Infections D010326 8 associated lipids
Occupational Diseases D009784 42 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Lymphadenitis D008199 8 associated lipids
Liver Abscess D008100 6 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Hyperplasia D006965 34 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Antunes NT et al. In vitro susceptibilities of Mycoplasma putrefaciens field isolates. 2007 Antimicrob. Agents Chemother. pmid:17638695
Nagaraja TG and Lechtenberg KF Liver abscesses in feedlot cattle. 2007 Vet. Clin. North Am. Food Anim. Pract. pmid:17606156
Murphy MW et al. Airborne antibiotic concentrations in a swine feeding operation. 2007 J Agric Saf Health pmid:18075012
Choi D et al. Tylosin production by Streptomyces fradiae using raw cornmeal in airlift bioreactor. 2007 J. Microbiol. Biotechnol. pmid:18051315
Nouri M and Constable PD Effect of parenteral administration of erythromycin, tilmicosin, and tylosin on abomasal emptying rate in suckling calves. 2007 Am. J. Vet. Res. pmid:18052746
Lawrence K Micotil: safe use and administration. 2007 Vet. Rec. pmid:18037699
Blackall PJ et al. Minimal inhibitory concentration of tilmicosin against isolates of Histophilus somni from Australian cattle. 2007 Aust. Vet. J. pmid:18042158
Allaire SE et al. Sorption kinetics of chlortetracyline and tylosin on sandy loam and heavy clay soils. 2006 Jul-Aug J. Environ. Qual. pmid:16738380
Fu H et al. Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides. 2006 Bioorg. Med. Chem. Lett. pmid:16343900
Chelliapan S et al. Performance of an up-flow anaerobic stage reactor (UASR) in the treatment of pharmaceutical wastewater containing macrolide antibiotics. 2006 Water Res. pmid:16387347
Peng Z and Bang-Ce Y Small molecule microarrays for drug residue detection in foodstuffs. 2006 J. Agric. Food Chem. pmid:16968051
DiLorenzo N et al. Effects of feeding polyclonal antibody preparations on ruminal bacterial populations and ruminal pH of steers fed high-grain diets. 2006 J. Anim. Sci. pmid:16864880
McAllister TA et al. Shedding of escherichia coli O157:H7 by cattle fed diets containing monensin or tylosin. 2006 J. Food Prot. pmid:16995508
Industry guidance on the administration of tilmicosin. 2006 Vet. Rec. pmid:16924727
Bate N et al. Regulation of tylosin biosynthesis involving 'SARP-helper' activity. 2006 Mol. Microbiol. pmid:16942604
Jacobsen AM and Halling-Sørensen B Multi-component analysis of tetracyclines, sulfonamides and tylosin in swine manure by liquid chromatography-tandem mass spectrometry. 2006 Anal Bioanal Chem pmid:16485090
Jung WS et al. Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae. 2006 Appl. Microbiol. Biotechnol. pmid:16493552
Carlson JC and Mabury SA Dissipation kinetics and mobility of chlortetracycline, tylosin, and monensin in an agricultural soil in Northumberland County, Ontario, Canada. 2006 Environ. Toxicol. Chem. pmid:16494218
Womble A et al. Pulmonary disposition of tilmicosin in foals and in vitro activity against Rhodococcus equi and other common equine bacterial pathogens. 2006 J. Vet. Pharmacol. Ther. pmid:17083461
Booker CW et al. An evaluation of the metaphylactic effect of ceftiofur crystalline free Acid in feedlot calves. 2006 Vet. Ther. pmid:17039449
Karahalios P et al. On the mechanism of action of 9-O-arylalkyloxime derivatives of 6-O-mycaminosyltylonolide, a new class of 16-membered macrolide antibiotics. 2006 Mol. Pharmacol. pmid:16873579
Hamscher G et al. Quantitative analysis of tylosin in eggs by high performance liquid chromatography with electrospray ionization tandem mass spectrometry: residue depletion kinetics after administration via feed and drinking water in laying hens. 2006 J. Agric. Food Chem. pmid:17117786
Veenhuizen MF et al. Analysis of reports of human exposure to Micotil 300 (tilmicosin injection). 2006 J. Am. Vet. Med. Assoc. pmid:17144818
Couper A et al. Treatment of pneumonia in pigs with long-acting injectable tylosin. 2006 Vet. Rec. pmid:17158711
Chun S et al. Influence of agricultural antibiotics and 17beta-estradiol on the microbial community of soil. 2006 J Environ Sci Health B pmid:16893780
Nozal Nalda MJ et al. Trace analysis of antibacterial tylosin A, B, C and D in honey by liquid chromatography-electrospray ionization-mass spectrometry. 2006 J Sep Sci pmid:16544883
Cao XY et al. Tilmicosin and tylosin have anti-inflammatory properties via modulation of COX-2 and iNOS gene expression and production of cytokines in LPS-induced macrophages and monocytes. 2006 Int. J. Antimicrob. Agents pmid:16647840
Dingwell RT et al. Influence of the genotype of Staphylococcus aureus, determined by pulsed-field gel electrophoresis, on dry-period elimination of subclinical mastitis in Canadian dairy herds. 2006 Can. J. Vet. Res. pmid:16639943
ter Laak TL et al. The effect of pH and ionic strength on the sorption of sulfachloropyridazine, tylosin, and oxytetracycline to soil. 2006 Environ. Toxicol. Chem. pmid:16629129
ter Laak TL et al. Estimation of soil sorption coefficients of veterinary pharmaceuticals from soil properties. 2006 Environ. Toxicol. Chem. pmid:16629132
Terui Y et al. Synthesis of 2-methyl 16-membered macrolide derived from tylosin. 2006 J. Antibiot. pmid:16629410
Jiang H et al. Residue depletion of tilmicosin in cattle after subcutaneous administration. 2006 J. Agric. Food Chem. pmid:16819937
Yang S et al. Trace analysis and occurrence of anhydroerythromycin and tylosin in influent and effluent wastewater by liquid chromatography combined with electrospray tandem mass spectrometry. 2006 Anal Bioanal Chem pmid:16715282
García-Mayor MA et al. Liquid chromatography-UV diode-array detection method for multi-residue determination of macrolide antibiotics in sheep's milk. 2006 J Chromatogr A pmid:16682049
Shakeri-Nejad K and Stahlmann R Drug interactions during therapy with three major groups of antimicrobial agents. 2006 Expert Opin Pharmacother pmid:16556082
Pringle M et al. Tiamulin resistance in porcine Brachyspira pilosicoli isolates. 2006 Res. Vet. Sci. pmid:16253666
Kim D et al. In vitro susceptibilities of Leptospira spp. and Borrelia burgdorferi isolates to amoxicillin, tilmicosin, and enrofloxacin. 2006 J. Vet. Sci. pmid:17106227
Westermarck E et al. Effect of diet and tylosin on chronic diarrhea in beagles. 2005 Nov-Dec J. Vet. Intern. Med. pmid:16355675
Chander Y et al. Antibacterial activity of soil-bound antibiotics. 2005 Nov-Dec J. Environ. Qual. pmid:16221813
Kumar K et al. Antibiotic uptake by plants from soil fertilized with animal manure. 2005 Nov-Dec J. Environ. Qual. pmid:16221828
Westermarck E et al. Tylosin-responsive chronic diarrhea in dogs. 2005 Mar-Apr J. Vet. Intern. Med. pmid:15822561
Liutskanova DG et al. [Increase in tylosin production by a commercial strain of Streptomyces fradiae]. 2005 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:15859462
Kolz AC et al. Degradation and metabolite production of tylosin in anaerobic and aerobic swine-manure lagoons. 2005 Jan-Feb Water Environ. Res. pmid:15765935
Rooklidge SJ et al. Modeling antimicrobial contaminant removal in slow sand filtration. 2005 Jan-Feb Water Res. pmid:15644241
Menozzi A et al. Effect of the macrolide antibacterial drug, tylosin, on TNBS-induced colitis in the rat. 2005 Pharmacology pmid:15756055
Rozeboom DW et al. Effects of mannan oligosaccharide and an antimicrobial product in nursery diets on performance of pigs reared on three different farms. 2005 J. Anim. Sci. pmid:16230663
Jensen LB and Aarestrup FM Regulation of the erm(C) gene in Staphylococci from reservoir with different usage of macrolides. 2005 Acta Vet. Scand. pmid:16261929
Ayling RD et al. Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection. 2005 Antimicrob. Agents Chemother. pmid:16304194
Brain RA et al. Aquatic microcosm assessment of the effects of tylosin on Lemna gibba and Myriophyllum spicatum. 2005 Environ. Pollut. pmid:15519715
Clay SA et al. Tylosin sorption to silty clay loam soils, swine manure, and sand. 2005 J Environ Sci Health B pmid:16194921