Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Poultry Diseases D011201 21 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Pasteurella Infections D010326 8 associated lipids
Occupational Diseases D009784 42 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Lymphadenitis D008199 8 associated lipids
Liver Abscess D008100 6 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Hyperplasia D006965 34 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Menozzi A et al. Effect of the macrolide antibacterial drug, tylosin, on TNBS-induced colitis in the rat. 2005 Pharmacology pmid:15756055
Pfister P et al. 23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A-->G. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15795375
Lu L et al. Autoinducer 2-like activity in poultry-associated enteric bacteria in response to subtherapeutic antibiotic exposure. 2005 Avian Dis. pmid:15839416
Loftin KA et al. Inhibition of microbial metabolism in anaerobic lagoons by selected sulfonamides, tetracyclines, lincomycin, and tylosin tartrate. 2005 Environ. Toxicol. Chem. pmid:15839550
Halling-Sørensen B et al. Dissipation and effects of chlortetracycline and tylosin in two agricultural soils: a field-scale study in southern Denmark. 2005 Environ. Toxicol. Chem. pmid:15839553
Wang J et al. Determination of five macrolide antibiotic residues in eggs using liquid chromatography/electrospray ionization tandem mass spectrometry. 2005 J. Agric. Food Chem. pmid:15769104
Blackwell PA et al. Evaluation of a lower tier exposure assessment model for veterinary medicines. 2005 J. Agric. Food Chem. pmid:15769156
Kay P et al. A lysimeter experiment to investigate the leaching of veterinary antibiotics through a clay soil and comparison with field data. 2005 Environ. Pollut. pmid:15589660
Thompson TS et al. Determination of lincomycin and tylosin residues in honey by liquid chromatography/tandem mass spectrometry. 2005 Rapid Commun. Mass Spectrom. pmid:15645470
Beier RC et al. Production and characterization of monoclonal antibodies against the antibiotic tilmicosin. 2005 J. Agric. Food Chem. pmid:16332115
Rozeboom DW et al. Effects of mannan oligosaccharide and an antimicrobial product in nursery diets on performance of pigs reared on three different farms. 2005 J. Anim. Sci. pmid:16230663
Jensen LB and Aarestrup FM Regulation of the erm(C) gene in Staphylococci from reservoir with different usage of macrolides. 2005 Acta Vet. Scand. pmid:16261929
Ayling RD et al. Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection. 2005 Antimicrob. Agents Chemother. pmid:16304194
Brain RA et al. Aquatic microcosm assessment of the effects of tylosin on Lemna gibba and Myriophyllum spicatum. 2005 Environ. Pollut. pmid:15519715
Godinho KS et al. Efficacy of tulathromycin in the treatment and prevention of natural outbreaks of bovine respiratory disease in European cattle. 2005 Vet. Ther. pmid:16094560
Kilgore WR et al. Clinical effectiveness of tulathromycin, a novel triamilide antimicrobial, for the control of respiratory disease in cattle at high risk for developing bovine respiratory disease. 2005 Vet. Ther. pmid:16094561
Kilgore WR et al. Therapeutic efficacy of tulathromycin, a novel triamilide antimicrobial, against bovine respiratory disease in feeder calves. 2005 Vet. Ther. pmid:16094562
Rooney KA et al. Efficacy of tulathromycin compared with tilmicosin and florfenicol for the control of respiratory disease in cattle at high risk of developing bovine respiratory disease. 2005 Vet. Ther. pmid:16094563
Nutsch RG et al. Comparative efficacy of tulathromycin, tilmicosin, and florfenicol in the treatment of bovine respiratory disease in stocker cattle. 2005 Vet. Ther. pmid:16094564
Skogerboe TL et al. Comparative efficacy of tulathromycin versus florfenicol and tilmicosin against undifferentiated bovine respiratory disease in feedlot cattle. 2005 Vet. Ther. pmid:16094565
Patterson J et al. Selected culturable enteric bacterial populations are modified by diet acidification and the growth promotant Tylosin. 2005 Lett. Appl. Microbiol. pmid:16033507
Kolz AC et al. Sorption of tylosin onto swine manure. 2005 Chemosphere pmid:15914248
Yong H et al. Design, synthesis and structure-activity relationships of 6-O-arylpropargyl diazalides with potent activity against multidrug-resistant Streptococcus pneumoniae. 2005 Bioorg. Med. Chem. Lett. pmid:15863336
Vicca J et al. Efficacy of in-feed medication with tylosin for the treatment and control of Mycoplasma hyopneumoniae infections. 2005 Vet. Rec. pmid:15879541
Fittipaldi N et al. Assessment of the efficacy of tilmicosin phosphate to eliminate Actinobacillus pleuropneumoniae from carrier pigs. 2005 Can. J. Vet. Res. pmid:15971680
Fang XM et al. [A study on space mutation of Streptomyces fradiae]. 2005 Space Med Med Eng (Beijing) pmid:15977391
Alippi AM et al. In vitro and in vivo susceptibility of the honeybee bacterial pathogen Paenibacillus larvae subsp. larvae to the antibiotic tylosin. 2005 Vet. Microbiol. pmid:15951140
Gramse MJ et al. Determination of tylosin in feeds by liquid chromatography with solid-phase extraction. 2004 Mar-Apr J AOAC Int pmid:15164825
Lee WD et al. Tilmicosin-induced bovine neutrophil apoptosis is cell-specific and downregulates spontaneous LTB4 synthesis without increasing Fas expression. 2004 Mar-Apr Vet. Res. pmid:15099497
Yildiz S et al. Tylosin does not affect GnRH-induced LH secretion in rams. 2004 Jan-Feb Reprod. Toxicol. pmid:15013072
Dykman LA et al. [Immunogenic properties of the colloidal gold]. 2004 Jan-Feb Izv. Akad. Nauk. Ser. Biol. pmid:15049073
Kumar K et al. Enzyme-linked immunosorbent assay for ultratrace determination of antibiotics in aqueous samples. 2004 Jan-Feb J. Environ. Qual. pmid:14964379
Mathers JJ et al. Inhibition of resistance plasmid transfer in Escherichia coli by ionophores, chlortetracycline, bacitracin, and ionophore/antimicrobial combinations. 2004 Apr-Jun Avian Dis. pmid:15283418
Taniguchi K et al. The role of histidine residues conserved in the putative ATP-binding region of macrolide 2'-phosphotransferase II. 2004 FEMS Microbiol. Lett. pmid:15033229
Paradis MA et al. Efficacy of tilmicosin in the control of experimentally induced Actinobacillus pleuropneumoniae infection in swine. 2004 Can. J. Vet. Res. pmid:14979429
Jost BH et al. A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes. 2004 Antimicrob. Agents Chemother. pmid:14982756
Douthwaite S et al. The tylosin-resistance methyltransferase RlmA(II) (TlrB) modifies the N-1 position of 23S rRNA nucleotide G748. 2004 J. Mol. Biol. pmid:15046978
Elitok B and Elitok OM Clinical efficacy of carprofen as an adjunct to the antibacterial treatment of bovine respiratory disease. 2004 J. Vet. Pharmacol. Ther. pmid:15500569
Clark C et al. A preliminary investigation of the disposition of tilmicosin residues in elk tissues and serum. 2004 J. Vet. Pharmacol. Ther. pmid:15500580
Civitareale C et al. Identification and quantification method of spiramycin and tylosin in feedingstuffs with HPLC-UV/DAD at 1 ppm level. 2004 J Pharm Biomed Anal pmid:15496324
Novotny GW et al. Ketolide antimicrobial activity persists after disruption of interactions with domain II of 23S rRNA. 2004 Antimicrob. Agents Chemother. pmid:15388419
Mutak S et al. Semisynthetic macrolide antibacterials derived from tylosin. Synthesis and structure-activity relationships of novel desmycosin analogues. 2004 J. Med. Chem. pmid:14711312
Phan LT et al. Synthesis and antibacterial activity of a novel class of 4'-substituted 16-membered ring macrolides derived from tylosin. 2004 J. Med. Chem. pmid:15163176
Brumbaugh GW et al. Susceptibility of Mycobacterium avium sbsp paratuberculosis to monensin sodium or tilmicosin phosphate in vitro and resulting infectivity in a murine model. 2004 Can. J. Vet. Res. pmid:15352541
Poole TL et al. Competitive exclusion of a glycopeptide-resistant Enterococcus faecium in the presence of vancomycin but not equivalent concentrations of tylosin or gentamicin. 2004 Poult. Sci. pmid:15285499
Lum AM et al. Reverse engineering of industrial pharmaceutical-producing actinomycete strains using DNA microarrays. 2004 Metab. Eng. pmid:15256208
Jackson CR et al. Effects of tylosin use on erythromycin resistance in enterococci isolated from swine. 2004 Appl. Environ. Microbiol. pmid:15240302
Lawrence K Change to user warning for Micotil. 2004 Vet. Rec. pmid:15200081
Kay P et al. Fate of veterinary antibiotics in a macroporous tile drained clay soil. 2004 Environ. Toxicol. Chem. pmid:15180364
Pettis JS et al. Larval Apis mellifera L. (Hymenoptera: Apidae) mortality after topical application of antibiotics and dusts. 2004 J. Econ. Entomol. pmid:15154433