Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Pyoderma D011711 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Campylobacter Infections D002169 13 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Liver Abscess D008100 6 associated lipids
Treponemal Infections D014211 3 associated lipids
Dysentery D004403 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Ayling RD et al. Comparison of in vitro activity of danofloxacin, florfenicol, oxytetracycline, spectinomycin and tilmicosin against recent field isolates of Mycoplasma bovis. 2000 Vet. Rec. pmid:10909906
Lawrence K Change to user warning for Micotil. 2004 Vet. Rec. pmid:15200081
Usui M et al. Selection of macrolide-resistant Campylobacter in pigs treated with macrolides. 2014 Vet. Rec. pmid:25163817
Tavío MM et al. In vitro activity of tylvalosin against Spanish field strains of Mycoplasma hyopneumoniae. 2014 Vet. Rec. pmid:25185108
Guedes RM et al. Use of tylvalosin-medicated feed to control porcine proliferative enteropathy. 2009 Vet. Rec. pmid:19767637
Fitzgerald J Administration of micotil. 2009 Vet. Rec. pmid:19767643
Blaha T et al. Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme. 1987 Vet. Rec. pmid:3424604
Ball HJ and Campbell JN Antibiotic treatment of experimental Mycoplasma californicum mastitis. 1989 Vet. Rec. pmid:2815518
Naccari F et al. Effectiveness and kinetic behaviour of tilmicosin in the treatment of respiratory infections in sheep. 2001 Vet. Rec. pmid:11465263
Lee WD et al. Tilmicosin-induced bovine neutrophil apoptosis is cell-specific and downregulates spontaneous LTB4 synthesis without increasing Fas expression. 2004 Mar-Apr Vet. Res. pmid:15099497
Gerchman I et al. Characterization of in vivo-acquired resistance to macrolides of Mycoplasma gallisepticum strains isolated from poultry. 2011 Vet. Res. pmid:21810258
Abu-Basha EA et al. Pharmacokinetics of tilmicosin (Provitil powder and Pulmotil liquid AC) oral formulations in chickens. 2007 Vet. Res. Commun. pmid:17225089
Gallina G et al. Acute toxicity evaluation of four antibacterials with Daphnia magna. 2008 Vet. Res. Commun. pmid:18688742
Gallina G et al. Kinetics and intrapulmonary disposition of tilmicosin after single and repeated oral bolus administrations to rabbits. 2010 Vet. Res. Commun. pmid:20480234
Saurit AR et al. Some comparative aspects of the pharmacokinetics of tylosin in buffaloes and cattle. 2002 Vet. Res. Commun. pmid:11860087
Godinho KS et al. Efficacy of tulathromycin in the treatment and prevention of natural outbreaks of bovine respiratory disease in European cattle. 2005 Vet. Ther. pmid:16094560
Kilgore WR et al. Clinical effectiveness of tulathromycin, a novel triamilide antimicrobial, for the control of respiratory disease in cattle at high risk for developing bovine respiratory disease. 2005 Vet. Ther. pmid:16094561
Kilgore WR et al. Therapeutic efficacy of tulathromycin, a novel triamilide antimicrobial, against bovine respiratory disease in feeder calves. 2005 Vet. Ther. pmid:16094562
Rooney KA et al. Efficacy of tulathromycin compared with tilmicosin and florfenicol for the control of respiratory disease in cattle at high risk of developing bovine respiratory disease. 2005 Vet. Ther. pmid:16094563
Nutsch RG et al. Comparative efficacy of tulathromycin, tilmicosin, and florfenicol in the treatment of bovine respiratory disease in stocker cattle. 2005 Vet. Ther. pmid:16094564