Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Kolz AC et al. Sorption of tylosin onto swine manure. 2005 Chemosphere pmid:15914248
Baguer AJ et al. Effects of the antibiotics oxytetracycline and tylosin on soil fauna. 2000 Chemosphere pmid:10705553
Loke ML et al. Stability of Tylosin A in manure containing test systems determined by high performance liquid chromatography. 2000 Chemosphere pmid:10705554
Ali M et al. Effect of redox potential and pH status on degradation and adsorption behavior of tylosin in dairy lagoon sediment suspension. 2013 Chemosphere pmid:23352520
Blackwell PA et al. Effects of agricultural conditions on the leaching behaviour of veterinary antibiotics in soils. 2009 Chemosphere pmid:19128817
Grdisa M et al. Effect of a 17-member azalide on tumor cell growth. 1998 Sep-Oct Chemotherapy pmid:9732149
Besserer F et al. Tilmicosin toxicity: a case of accidental human tilmicosin injection managed with calcium, high-dose insulin and intravenous lipid emulsion therapy. 2016 Clin Toxicol (Phila) pmid:27207720
Blackwood RS et al. Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta). 2008 Comp. Med. pmid:19793461
Tuomi ML and Räsänen L Contact allergy to tylosin and cobalt in a pig-farmer. 1995 Contact Derm. pmid:8654098
Caraffini S et al. Tylosin, an airborne contact allergen in veterinarians. 1994 Contact Derm. pmid:7867337
Danese P et al. Occupational contact dermatitis from tylosin. 1994 Contact Derm. pmid:8187499
Whitehead TR and Cotta MA Sequence analyses of a broad host-range plasmid containing ermT from a tylosin-resistant Lactobacillus sp. Isolated from swine feces. 2001 Curr. Microbiol. pmid:11375658
Zhang AJ and Warshaw EM Pet Consort Dermatitis: The Importance of Asking About Pets. Dermatitis pmid:29901502
Malaiyandi V et al. Airborne allergic contact dermatitis from tylosin in pharmacy compounders and cross-sensitization to macrolide antibiotics. 2012 Sep-Oct Dermatitis pmid:23010831
Jung HD [Occupationally-induced contact eczema by tylosin (Tylan)]. 1983 Dermatol Monatsschr pmid:6222923
Song M et al. The controlled release of tilmicosin from silica nanoparticles. 2011 Drug Dev Ind Pharm pmid:21204738
Atef M et al. Effect of albendazole administration on pharmacokinetic aspects of tylosin in lactating goats. 2009 Drug Metab Lett pmid:19702546
Nathues H and grosse Beilage E Diagnosis of Lawsonia intracellularis infection in pigs after vaccination or antimicrobial treatment. 2008 DTW. Dtsch. Tierarztl. Wochenschr. pmid:19024547
Atef M et al. Disposition of tylosin in goats. 1991 DTW. Dtsch. Tierarztl. Wochenschr. pmid:1790764
Kietzmann M [Comparative study of the distribution and excretion of tylosin of various origins]. 1985 DTW. Dtsch. Tierarztl. Wochenschr. pmid:3899580