Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Fouces R et al. Conjugation and transformation of Streptomyces species by tylosin resistance. 2000 FEMS Microbiol. Lett. pmid:10802191
Wu CM et al. Induction of macrolide resistance in Mycoplasma gallisepticum in vitro and its resistance-related mutations within domain V of 23S rRNA. 2005 FEMS Microbiol. Lett. pmid:15936901
Rezanka T et al. Isobutyrate as a precursor of n-butyrate in the biosynthesis of tylosine and fatty acids. 1991 FEMS Microbiol. Lett. pmid:1769552
Fujiwara T and Takenaka S Bioconversion of 19-deformyl-5-O-desosaminyl tylonolide to 19-deformyl-4'-deoxydesmycosin (TMC-016). 1990 FEMS Microbiol. Lett. pmid:2379808
Higgins HC and McEvoy JD Accelerated solvent extraction of animal feedingstuffs for microbial growth inhibition screening for the presence of antimicrobial feed additives. 2002 Food Addit Contam pmid:12396393
Montesissa C et al. Tylosin depletion in edible tissues of turkeys. 1999 Food Addit Contam pmid:10755131
Koenen-Dierick K and De Beer JO Optimization of an antibiotic residue screening test, based on inhibition of Bacillus subtilis BGA, with experimental design. 1998 Food Addit Contam pmid:9829036
Vincent U et al. Validation of an analytical method for the determination of spiramycin, virginiamycin and tylosin in feeding-stuffs by thin-layer chromatography and bio-autography. 2007 Food Addit Contam pmid:17454108
Patyra E et al. Development and validation of an LC-MS/MS method for the quantification of tiamulin, trimethoprim, tylosin, sulfadiazine and sulfamethazine in medicated feed. 2018 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:29324179
Cornejo J et al. Depletion of tylosin residues in feathers, muscle and liver from broiler chickens after completion of antimicrobial therapy. 2018 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:29111882
De Baere S et al. In vitro model to assess the adsorption of oral veterinary drugs to mycotoxin binders in a feed- and aflatoxin B1-containing buffered matrix. 2018 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:30016205
Le T et al. A quantum dot-based immunoassay for screening of tylosin and tilmicosin in edible animal tissues. 2015 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:25822697
Stead SL et al. Development and validation of a potentiometric biosensor assay for tylosin with demonstrated applicability for the detection of two other antimicrobial growth-promoter compounds in feedstuffs. 2011 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:21574083
Gaudin V et al. Validation of two ELISA kits for the screening of tylosin and streptomycin in honey according to the European decision 2002/657/EC. 2013 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:23013044
Pol-Hofstad I et al. Collaborative study of a microbiological screening method (three-plate) for the banned antimicrobial growth promotors tylosin, virginiamycin, spiramycin, zinc bacitracin and avoparcin in animal feed. 2008 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:19680856
Baggio A et al. Residues of antibacterial drugs in honey from the Italian market. 2009 Food Addit Contam Part B Surveill pmid:24784967
Molognoni L et al. Development of a LC-MS/MS method for the simultaneous determination of sorbic acid, natamycin and tylosin in Dulce de leche. 2016 Food Chem pmid:27283692
Ramlachan N et al. A comparative study on the effects of tylosin on select bacteria during continuous flow culture of mixed populations of gut microflora derived from a feral and a domestic pig. 2008 Foodborne Pathog. Dis. pmid:18260812
Amachawadi RG et al. Effects of In-Feed Copper, Chlortetracycline, and Tylosin on the Prevalence of Transferable Copper Resistance Gene, tcrB, Among Fecal Enterococci of Weaned Piglets. 2015 Foodborne Pathog. Dis. pmid:26258261
Lin J et al. Response of intestinal microbiota to antibiotic growth promoters in chickens. 2013 Foodborne Pathog. Dis. pmid:23461609