Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Stone JJ et al. Land application of tylosin and chlortetracycline swine manure: Impacts to soil nutrients and soil microbial community structure. 2011 J Environ Sci Health B pmid:21877979
Krokidis M et al. The slow dissociation rate of K-1602 contributes to the enhanced inhibitory activity of this novel alkyl-aryl-bearing fluoroketolide. 2016 J Enzyme Inhib Med Chem pmid:25807301
Kolanović BS et al. Tylosin content in meat and honey samples over a two-year period in Croatia. 2014 J Immunoassay Immunochem pmid:24063615
Oakes J and Seifert S American association of poison control centers database characterization of human tilmicosin exposures, 2001-2005. 2008 J Med Toxicol pmid:19031373
Pérez RA et al. Analysis of macrolide antibiotics in water by magnetic solid-phase extraction and liquid chromatography-tandem mass spectrometry. 2017 J Pharm Biomed Anal pmid:28858671
Civitareale C et al. Identification and quantification method of spiramycin and tylosin in feedingstuffs with HPLC-UV/DAD at 1 ppm level. 2004 J Pharm Biomed Anal pmid:15496324
Paesen J et al. Study of the stability of tylosin A in aqueous solutions. 1995 J Pharm Biomed Anal pmid:8573642
Danielson ND et al. Simple methods for the qualitative identification and quantitative determination of macrolide antibiotics. 1993 J Pharm Biomed Anal pmid:8504183
González de la Huebra MJ et al. Sample preparation strategy for the simultaneous determination of macrolide antibiotics in animal feedingstuffs by liquid chromatography with electrochemical detection (HPLC-ECD). 2007 J Pharm Biomed Anal pmid:17257795
Duthu GS Interspecies correlation of the pharmacokinetics of erythromycin, oleandomycin, and tylosin. 1985 J Pharm Sci pmid:4067847
Thurman GD et al. Diagnosis and successful treatment of subacute erysipelas in a captive dolphin. 1983 J S Afr Vet Assoc pmid:6655661
Gummow B et al. The diagnosis and treatment of bovine genital ureaplasmosis: a case study. 1992 J S Afr Vet Assoc pmid:1404223
Nozal Nalda MJ et al. Trace analysis of antibacterial tylosin A, B, C and D in honey by liquid chromatography-electrospray ionization-mass spectrometry. 2006 J Sep Sci pmid:16544883
Sehati N et al. Extraction and preconcentration of tylosin from milk samples through functionalized TiOâ‚‚ nanoparticles reinforced with a hollow fiber membrane as a novel solid/liquid-phase microextraction technique. 2014 J Sep Sci pmid:24890459
Liu YM et al. Sensitive determination of tilmicosin, erythromycin ethylsuccinate and clindamycin by CE with electrochemiluminescence detection using azithromycin as internal standard and its applications. 2010 J Sep Sci pmid:20235137
Ashenafi D et al. An improved liquid chromatographic method for the analysis of tylosin and its impurities. 2011 J Sep Sci pmid:21812113
Kart A et al. The possible protective effect of L-carnitine on tilmicosin-induced cardiotoxicity in mice. 2007 J Vet Med A Physiol Pathol Clin Med pmid:17381679
Litterio NJ et al. Microbiological screening test validation for detection of tylosin excretion in milk of cows with low and high somatic cell counts. 2007 J Vet Med A Physiol Pathol Clin Med pmid:17359452
Hamscher G et al. Quantitative analysis of tylosin in eggs by high performance liquid chromatography with electrospray ionization tandem mass spectrometry: residue depletion kinetics after administration via feed and drinking water in laying hens. 2006 J. Agric. Food Chem. pmid:17117786
Van Poucke C et al. Tylosin detection in animal feed by liquid chromatography-tandem mass spectrometry with enzymatic hydrolysis of the tylosin urea adduct. 2004 J. Agric. Food Chem. pmid:15137817