Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Cerdá RO et al. Impact of the type of catheter on the absorption of tylvalosin (acetylvaleryltylosin) administered orally to broiler chickens. 2010 J. Vet. Pharmacol. Ther. pmid:20444046
Shakya T and Wright GD Nucleotide selectivity of antibiotic kinases. 2010 Antimicrob. Agents Chemother. pmid:20231391
Liu YM et al. Sensitive determination of tilmicosin, erythromycin ethylsuccinate and clindamycin by CE with electrochemiluminescence detection using azithromycin as internal standard and its applications. 2010 J Sep Sci pmid:20235137
Catania S et al. Treatment of eggshell abnormalities and reduced egg production caused by Mycoplasma synoviae infection. 2010 Avian Dis. pmid:20608549
Alatrache A et al. Tylosin abatement in water by photocatalytic process. 2010 Water Sci. Technol. pmid:20651450
Barbour EK et al. Impact of synergism of calcium phosphomycin/tylosin tartarate supplements on the performance of broilers in the Lebanon. 2010 Jan-Mar Vet. Ital. pmid:20391366
Sumbatian NV et al. [Amino acid and peptide derivatives of the tylosin family of macrolide antibiotics modified at the aldehyde group]. 2010 Mar-Apr Bioorg. Khim. pmid:20531486
Reynaldi FJ et al. [Binding of tylosin, tilmicosin and oxytetracycline to proteins from honeybees, larvae and beehive products]. 2010 Oct-Dec Rev. Argent. Microbiol. pmid:21229198
Bernal J et al. Determination of tylosins A, B, C and D in bee larvae by liquid chromatography coupled to ion trap-tandem mass spectrometry. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21498134
Smee NM and Towell TL What is the evidence? Inflammatory bowel disease in a dog. 2011 J. Am. Vet. Med. Assoc. pmid:21529230
Kilpinen S et al. Effect of tylosin on dogs with suspected tylosin-responsive diarrhea: a placebo-controlled, randomized, double-blinded, prospective clinical trial. 2011 Acta Vet. Scand. pmid:21489311
Alexander TW et al. Longitudinal characterization of antimicrobial resistance genes in feces shed from cattle fed different subtherapeutic antibiotics. 2011 BMC Microbiol. pmid:21261985
Ozaki H et al. Antimicrobial resistance in fecal Escherichia coli isolated from growing chickens on commercial broiler farms. 2011 Vet. Microbiol. pmid:21232883
Song M et al. The controlled release of tilmicosin from silica nanoparticles. 2011 Drug Dev Ind Pharm pmid:21204738
Stead SL et al. Development and validation of a potentiometric biosensor assay for tylosin with demonstrated applicability for the detection of two other antimicrobial growth-promoter compounds in feedstuffs. 2011 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:21574083
Kucerova Z et al. Antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolates from clinical outbreaks of porcine respiratory diseases. 2011 Vet. Microbiol. pmid:21316872
Guan S et al. Immunosuppressive activity of tilmicosin on the immune responses in mice. 2011 Immunopharmacol Immunotoxicol pmid:20718577
Lombardi KR et al. Pharmacokinetics of tilmicosin in beef cattle following intravenous and subcutaneous administration. 2011 J. Vet. Pharmacol. Ther. pmid:21323676
Xie S et al. Acute toxicity study of tilmicosin-loaded hydrogenated castor oil-solid lipid nanoparticles. 2011 Part Fibre Toxicol pmid:22098626
Lust EB et al. Human health hazards of veterinary medications: information for emergency departments. 2011 J Emerg Med pmid:20045604