Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Primate Diseases D018419 2 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Digital Dermatitis D058066 3 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Fu H et al. Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides. 2006 Bioorg. Med. Chem. Lett. pmid:16343900
Chelliapan S et al. Performance of an up-flow anaerobic stage reactor (UASR) in the treatment of pharmaceutical wastewater containing macrolide antibiotics. 2006 Water Res. pmid:16387347
Peng Z and Bang-Ce Y Small molecule microarrays for drug residue detection in foodstuffs. 2006 J. Agric. Food Chem. pmid:16968051
DiLorenzo N et al. Effects of feeding polyclonal antibody preparations on ruminal bacterial populations and ruminal pH of steers fed high-grain diets. 2006 J. Anim. Sci. pmid:16864880
McAllister TA et al. Shedding of escherichia coli O157:H7 by cattle fed diets containing monensin or tylosin. 2006 J. Food Prot. pmid:16995508
Industry guidance on the administration of tilmicosin. 2006 Vet. Rec. pmid:16924727
Bate N et al. Regulation of tylosin biosynthesis involving 'SARP-helper' activity. 2006 Mol. Microbiol. pmid:16942604
Jacobsen AM and Halling-Sørensen B Multi-component analysis of tetracyclines, sulfonamides and tylosin in swine manure by liquid chromatography-tandem mass spectrometry. 2006 Anal Bioanal Chem pmid:16485090
Jung WS et al. Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae. 2006 Appl. Microbiol. Biotechnol. pmid:16493552
Carlson JC and Mabury SA Dissipation kinetics and mobility of chlortetracycline, tylosin, and monensin in an agricultural soil in Northumberland County, Ontario, Canada. 2006 Environ. Toxicol. Chem. pmid:16494218
Womble A et al. Pulmonary disposition of tilmicosin in foals and in vitro activity against Rhodococcus equi and other common equine bacterial pathogens. 2006 J. Vet. Pharmacol. Ther. pmid:17083461
Booker CW et al. An evaluation of the metaphylactic effect of ceftiofur crystalline free Acid in feedlot calves. 2006 Vet. Ther. pmid:17039449
Chun S et al. Influence of agricultural antibiotics and 17beta-estradiol on the microbial community of soil. 2006 J Environ Sci Health B pmid:16893780
Nozal Nalda MJ et al. Trace analysis of antibacterial tylosin A, B, C and D in honey by liquid chromatography-electrospray ionization-mass spectrometry. 2006 J Sep Sci pmid:16544883
Cao XY et al. Tilmicosin and tylosin have anti-inflammatory properties via modulation of COX-2 and iNOS gene expression and production of cytokines in LPS-induced macrophages and monocytes. 2006 Int. J. Antimicrob. Agents pmid:16647840
Dingwell RT et al. Influence of the genotype of Staphylococcus aureus, determined by pulsed-field gel electrophoresis, on dry-period elimination of subclinical mastitis in Canadian dairy herds. 2006 Can. J. Vet. Res. pmid:16639943
ter Laak TL et al. The effect of pH and ionic strength on the sorption of sulfachloropyridazine, tylosin, and oxytetracycline to soil. 2006 Environ. Toxicol. Chem. pmid:16629129
ter Laak TL et al. Estimation of soil sorption coefficients of veterinary pharmaceuticals from soil properties. 2006 Environ. Toxicol. Chem. pmid:16629132
Terui Y et al. Synthesis of 2-methyl 16-membered macrolide derived from tylosin. 2006 J. Antibiot. pmid:16629410
Jiang H et al. Residue depletion of tilmicosin in cattle after subcutaneous administration. 2006 J. Agric. Food Chem. pmid:16819937
Yang S et al. Trace analysis and occurrence of anhydroerythromycin and tylosin in influent and effluent wastewater by liquid chromatography combined with electrospray tandem mass spectrometry. 2006 Anal Bioanal Chem pmid:16715282
García-Mayor MA et al. Liquid chromatography-UV diode-array detection method for multi-residue determination of macrolide antibiotics in sheep's milk. 2006 J Chromatogr A pmid:16682049
Pringle M et al. Tiamulin resistance in porcine Brachyspira pilosicoli isolates. 2006 Res. Vet. Sci. pmid:16253666
Allaire SE et al. Sorption kinetics of chlortetracyline and tylosin on sandy loam and heavy clay soils. 2006 Jul-Aug J. Environ. Qual. pmid:16738380
Sassman SA et al. Sorption of tylosin A, D, and A-aldol and degradation of tylosin A in soils. 2007 Environ. Toxicol. Chem. pmid:17702335
Lüthje P and Schwarz S Molecular analysis of constitutively expressed erm(C) genes selected in vitro in the presence of the non-inducers pirlimycin, spiramycin and tylosin. 2007 J. Antimicrob. Chemother. pmid:17085767
Szczepanowski R et al. Novel macrolide resistance module carried by the IncP-1beta resistance plasmid pRSB111, isolated from a wastewater treatment plant. 2007 Antimicrob. Agents Chemother. pmid:17101677
Bignell DR et al. Regulation of tylosin production: role of a TylP-interactive ligand. 2007 Mol. Microbiol. pmid:17181783
Abu-Basha EA et al. Pharmacokinetics of tilmicosin (Provitil powder and Pulmotil liquid AC) oral formulations in chickens. 2007 Vet. Res. Commun. pmid:17225089
McDougall S et al. Parenteral treatment of clinical mastitis with tylosin base or penethamate hydriodide in dairy cattle. 2007 J. Dairy Sci. pmid:17235155
Blackwell PA et al. The dissipation and transport of veterinary antibiotics in a sandy loam soil. 2007 Chemosphere pmid:17204303
Elkins CA and Mullis LB Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. 2007 Antimicrob. Agents Chemother. pmid:17210767
Booker CW et al. Evaluation of the efficacy of tulathromycin as a metaphylactic antimicrobial in feedlot calves. 2007 Vet. Ther. pmid:17926304
Boissevain I [Punishment after the fact]. 2007 Tijdschr Diergeneeskd pmid:17939495
González de la Huebra MJ et al. Sample preparation strategy for the simultaneous determination of macrolide antibiotics in animal feedingstuffs by liquid chromatography with electrochemical detection (HPLC-ECD). 2007 J Pharm Biomed Anal pmid:17257795
Thompson TS et al. Degradation of incurred tylosin to desmycosin--implications for residue analysis of honey. 2007 Anal. Chim. Acta pmid:17386728
Hu D and Coats JR Aerobic degradation and photolysis of tylosin in water and soil. 2007 Environ. Toxicol. Chem. pmid:17521133
Song W et al. Determination of amprolium, carbadox, monensin, and tylosin in surface water by liquid chromatography/tandem mass spectrometry. 2007 Rapid Commun. Mass Spectrom. pmid:17510929
Vincent U et al. Validation of an analytical method for the determination of spiramycin, virginiamycin and tylosin in feeding-stuffs by thin-layer chromatography and bio-autography. 2007 Food Addit Contam pmid:17454108
Berrang ME et al. Subtherapeutic tylosin phosphate in broiler feed affects Campylobacter on carcasses during processing. 2007 Poult. Sci. pmid:17495097
Herrera M et al. Quantitative determination of tilmicosin in canine serum by high performance liquid chromatography-tandem mass spectrometry. 2007 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:17627909
Xie W et al. [Determination of five macrolide antibiotic residues in royal jelly samples by using high performance liquid chromatography tandem mass spectrometry]. 2007 Se Pu pmid:17679440
Werner JJ et al. Environmental photochemistry of tylosin: efficient, reversible photoisomerization to a less-active isomer, followed by photolysis. 2007 J. Agric. Food Chem. pmid:17655244
Antunes NT et al. In vitro susceptibilities of Mycoplasma putrefaciens field isolates. 2007 Antimicrob. Agents Chemother. pmid:17638695
Nagaraja TG and Lechtenberg KF Liver abscesses in feedlot cattle. 2007 Vet. Clin. North Am. Food Anim. Pract. pmid:17606156
Murphy MW et al. Airborne antibiotic concentrations in a swine feeding operation. 2007 J Agric Saf Health pmid:18075012
Choi D et al. Tylosin production by Streptomyces fradiae using raw cornmeal in airlift bioreactor. 2007 J. Microbiol. Biotechnol. pmid:18051315
Nouri M and Constable PD Effect of parenteral administration of erythromycin, tilmicosin, and tylosin on abomasal emptying rate in suckling calves. 2007 Am. J. Vet. Res. pmid:18052746
Lawrence K Micotil: safe use and administration. 2007 Vet. Rec. pmid:18037699
Blackall PJ et al. Minimal inhibitory concentration of tilmicosin against isolates of Histophilus somni from Australian cattle. 2007 Aust. Vet. J. pmid:18042158