Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Primate Diseases D018419 2 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Digital Dermatitis D058066 3 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Herd MB et al. Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus. 2013 J. Neurosci. pmid:24027285
Zhang Q et al. Sorption of tylosin on clay minerals. 2013 Chemosphere pmid:24007614
García-Sánchez L et al. Occurrence of tylosin in swine wastewater in Mexico. 2013 Water Sci. Technol. pmid:23985521
Svartström O et al. Characterization of Treponema spp. isolates from pigs with ear necrosis and shoulder ulcers. 2013 Vet. Microbiol. pmid:23948134
Buß M et al. Quality control ranges for tylosin 30 μg and 15 μg discs applicable to Staphylococcus aureus ATCC(R) 25923. 2014 J. Antimicrob. Chemother. pmid:23928021
Panfilova ZI et al. [Obtaining of mutants of Streptomyces fradiae producing tylosin by action of nitrosomethylurea on synchronously germinating spores]. 1990 Antibiot. Khimioter. pmid:2383150
Mitchell JD et al. In vitro pharmacodynamics of gamithromycin against Mycoplasma mycoides subspecies mycoides Small Colony. 2013 Vet. J. pmid:23810743
Fujiwara T and Takenaka S Bioconversion of 19-deformyl-5-O-desosaminyl tylonolide to 19-deformyl-4'-deoxydesmycosin (TMC-016). 1990 FEMS Microbiol. Lett. pmid:2379808
Topp E et al. Accelerated Biodegradation of Veterinary Antibiotics in Agricultural Soil following Long-Term Exposure, and Isolation of a Sulfamethazine-degrading sp. J. Environ. Qual. pmid:23673752
Amachawadi RG et al. Occurrence of the transferable copper resistance gene tcrB among fecal enterococci of U.S. feedlot cattle fed copper-supplemented diets. 2013 Appl. Environ. Microbiol. pmid:23666328
Chopra S et al. Characterization of impurities in tylosin using dual liquid chromatography combined with ion trap mass spectrometry. 2013 Talanta pmid:23598092
Pan R et al. Extraction of trace tilmicosin in real water samples using ionic liquid-based aqueous two-phase systems. 2013 Water Sci. Technol. pmid:23579819
Garcés-Narro C et al. Efficacy of low-dose tylvalosin for the control of clostridiosis in broilers and its effect on productive parameters. 2013 Poult. Sci. pmid:23472021
Lin J et al. Response of intestinal microbiota to antibiotic growth promoters in chickens. 2013 Foodborne Pathog. Dis. pmid:23461609
Meyer NF et al. Effects of monensin and tylosin in finishing diets containing corn wet distillers grains with solubles with differing corn processing methods. 2013 J. Anim. Sci. pmid:23422007
Pinckney JL et al. Sublethal effects of the antibiotic tylosin on estuarine benthic microalgal communities. 2013 Mar. Pollut. Bull. pmid:23398744
Holman DB and Chénier MR Impact of subtherapeutic administration of tylosin and chlortetracycline on antimicrobial resistance in farrow-to-finish swine. 2013 FEMS Microbiol. Ecol. pmid:23397987
Ali M et al. Effect of redox potential and pH status on degradation and adsorption behavior of tylosin in dairy lagoon sediment suspension. 2013 Chemosphere pmid:23352520
MiliavskiÄ­ EB et al. [Electrophoretic separation of spores of producers of kanamycin and tylosin]. 1990 Antibiot. Khimioter. pmid:2334246
Whitehead TR and Cotta MA Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. 2013 Lett. Appl. Microbiol. pmid:23297734
Hao H et al. Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. 2013 Antimicrob. Agents Chemother. pmid:23274667
Fujiwara T et al. Absorption, tissue distribution and excretion of 19-deformyldesmycosin derivatives, new 16-membered macrolides, in mice. 1990 J. Antibiot. pmid:2324015
Burkin MA and Galvidis IA Hapten modification approach for switching immunoassay specificity from selective to generic. 2013 J. Immunol. Methods pmid:23234756
Tsutsui A et al. Antimalarial C-9 oxime derivatives from desmycosin, produced by click chemistry. 2013 J. Antibiot. pmid:23232930
Er A and Yazar E Effects of tylosin, tilmicosin and tulathromycin on inflammatory mediators in bronchoalveolar lavage fluid of lipopolysaccharide-induced lung injury. 2012 Acta Vet. Hung. pmid:23160029
Westermarck E and Wiberg M Exocrine pancreatic insufficiency in the dog: historical background, diagnosis, and treatment. 2012 Top Companion Anim Med pmid:23148848
Del Pozo Sacristán R et al. Efficacy of in-feed medication with chlortetracycline in a farrow-to-finish herd against a clinical outbreak of respiratory disease in fattening pigs. 2012 Dec 22-29 Vet. Rec. pmid:23136309
Devreese M et al. An in vitro model using the IPEC-J2 cell line for efficacy and drug interaction testing of mycotoxin detoxifying agents. 2013 Toxicol In Vitro pmid:23078954
Gaudin V et al. Validation of two ELISA kits for the screening of tylosin and streptomycin in honey according to the European decision 2002/657/EC. 2013 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:23013044
Malaiyandi V et al. Airborne allergic contact dermatitis from tylosin in pharmacy compounders and cross-sensitization to macrolide antibiotics. 2012 Sep-Oct Dermatitis pmid:23010831
Kim HB et al. Microbial shifts in the swine distal gut in response to the treatment with antimicrobial growth promoter, tylosin. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22955886
Liu Y et al. Transcriptional profiling of Haemophilus parasuis SH0165 response to tilmicosin. 2012 Microb. Drug Resist. pmid:22935051
Andersen NM et al. Inhibition of protein synthesis on the ribosome by tildipirosin compared with other veterinary macrolides. 2012 Antimicrob. Agents Chemother. pmid:22926570
Vandenberge V et al. Transfer of flubendazole and tylosin from feed at cross-contamination levels to various poultry matrices. 2012 Poult. Sci. pmid:22912473
Coleman MR and Mowrey DH Turbidimetric assay of tylosin in animal feeds containing urea. 1990 Nov-Dec J Assoc Off Anal Chem pmid:2289924
Srinivasan P et al. Development of an HPLC method to analyze four veterinary antibiotics in soils and aqueous media and validation through fate studies. 2012 J Environ Sci Health A Tox Hazard Subst Environ Eng pmid:22871010
Sakai A et al. Production of a hybrid 16-membered macrolide antibiotic by genetic engineering of Micromonospora sp. TPMA0041. 2012 J. Ind. Microbiol. Biotechnol. pmid:22842988
Hagenbuch IM and Pinckney JL Toxic effect of the combined antibiotics ciprofloxacin, lincomycin, and tylosin on two species of marine diatoms. 2012 Water Res. pmid:22819871
Abutarbush SM et al. Comparison of enrofloxacin and ceftiofur sodium for the treatment of relapse of undifferentiated fever/bovine respiratory disease in feedlot cattle. 2012 Can. Vet. J. pmid:22753964
Jeong CY et al. Effect of biochar amendment on tylosin adsorption-desorption and transport in two different soils. 2012 Jul-Aug J. Environ. Qual. pmid:22751061
Devreese M et al. Interaction between tylosin and bentonite clay from a pharmacokinetic perspective. 2012 Vet. J. pmid:22749117
Granados-Chinchilla F et al. A novel green chemistry method for nonaqueous extraction and high-performance liquid chromatography detection of first-, second-, and third-generation tetracyclines, 4-epitetracycline, and tylosin in animal feeds. 2012 J. Agric. Food Chem. pmid:22738432
Blondeau JM et al. Comparative minimum inhibitory and mutant prevention drug concentrations of enrofloxacin, ceftiofur, florfenicol, tilmicosin and tulathromycin against bovine clinical isolates of Mannheimia haemolytica. 2012 Vet. Microbiol. pmid:22677482
Kim HY et al. Biochemical effects of veterinary antibiotics on proliferation and cell cycle arrest of human HEK293 cells. 2012 Bull Environ Contam Toxicol pmid:22673765
Eguchi K et al. Establishment of evaluation method to determine effects of veterinary medicinal products on manure fermentation using small-scale composting apparatus. 2012 J. Biosci. Bioeng. pmid:22595343
Poehlsgaard J et al. Visualizing the 16-membered ring macrolides tildipirosin and tilmicosin bound to their ribosomal site. 2012 ACS Chem. Biol. pmid:22563863
Morris FE et al. Effect of rotating monensin plus tylosin and lasalocid on performance, ruminal fermentation, and site and extent of digestion in feedlot cattle. 1990 J. Anim. Sci. pmid:2254185
Rose M et al. Pharmacokinetics of tildipirosin in porcine plasma, lung tissue, and bronchial fluid and effects of test conditions on in vitro activity against reference strains and field isolates of Actinobacillus pleuropneumoniae. 2013 J. Vet. Pharmacol. Ther. pmid:22500881
Vandenberge V et al. Transfer of flubendazole and tylosin at cross contamination levels in the feed to egg matrices and distribution between egg yolk and egg white. 2012 Poult. Sci. pmid:22499885
Persoons D et al. Antimicrobial use in Belgian broiler production. 2012 Prev. Vet. Med. pmid:22459488
Roudaut B and Moretain JP Residues of macrolide antibiotics in eggs following medication of laying hens. 1990 Br. Poult. Sci. pmid:2245358
Apley MD et al. Use estimates of in-feed antimicrobials in swine production in the United States. 2012 Foodborne Pathog. Dis. pmid:22324295
Huber ML et al. Branched-chain fatty acids produced by mutants of Streptomyces fradiae, putative precursors of the lactone ring of tylosin. 1990 Antimicrob. Agents Chemother. pmid:2221862
Menge M et al. Pharmacokinetics of tildipirosin in bovine plasma, lung tissue, and bronchial fluid (from live, nonanesthetized cattle). 2012 J. Vet. Pharmacol. Ther. pmid:22188102
Peng D et al. Development and validation of an indirect competitive enzyme-linked immunosorbent assay for the screening of tylosin and tilmicosin in muscle, liver, milk, honey and eggs. 2012 J. Agric. Food Chem. pmid:22136611
Giordano R et al. Effect of a high dose of three antibiotics on the reproduction of a parthenogenetic strain of Folsomia candida (Isotomidae: Collembola). 2010 Environ. Entomol. pmid:22127168
Danzeisen JL et al. Modulations of the chicken cecal microbiome and metagenome in response to anticoccidial and growth promoter treatment. 2011 PLoS ONE pmid:22114729
Forrester CA et al. Mycoplasma gallisepticum in pheasants and the efficacy of tylvalosin to treat the disease. 2011 Avian Pathol. pmid:22107092
Xie S et al. Acute toxicity study of tilmicosin-loaded hydrogenated castor oil-solid lipid nanoparticles. 2011 Part Fibre Toxicol pmid:22098626
Pakpour S et al. Frequency of antibiotic resistance in a swine facility 2.5 years after a ban on antibiotics. 2012 Microb. Ecol. pmid:21997543
Rérat M et al. Bovine respiratory disease: efficacy of different prophylactic treatments in veal calves and antimicrobial resistance of isolated Pasteurellaceae. 2012 Prev. Vet. Med. pmid:21945813
Wang XF et al. Enhancement of antibacterial activity of tilmicosin against Staphylococcus aureus by solid lipid nanoparticles in vitro and in vivo. 2012 Vet. J. pmid:21900026
Stone JJ et al. Land application of tylosin and chlortetracycline swine manure: Impacts to soil nutrients and soil microbial community structure. 2011 J Environ Sci Health B pmid:21877979
Chelliapan S et al. Tolerance of the antibiotic tylosin on treatment performance of an up-flow anaerobic stage reactor (UASR). 2011 Water Sci. Technol. pmid:21866757
Kim KR et al. Decline in extractable antibiotics in manure-based composts during composting. 2012 Waste Manag pmid:21865024
Ashenafi D et al. An improved liquid chromatographic method for the analysis of tylosin and its impurities. 2011 J Sep Sci pmid:21812113
Gerchman I et al. Characterization of in vivo-acquired resistance to macrolides of Mycoplasma gallisepticum strains isolated from poultry. 2011 Vet. Res. pmid:21810258
Dinh QT et al. Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. 2011 Talanta pmid:21807177
Bohm DA et al. Preparation and characterisation of in-house reference material of tylosin in honey and results of a proficiency test. 2011 Anal. Chim. Acta pmid:21742117
Bosi P et al. Feed supplemented with 3 different antibiotics improved food intake and decreased the activation of the humoral immune response in healthy weaned pigs but had differing effects on intestinal microbiota. 2011 J. Anim. Sci. pmid:21724943
McClary DG et al. Relationship of in vitro minimum inhibitory concentrations of tilmicosin against Mannheimia haemolytica and Pasteurella multocida and in vivo tilmicosin treatment outcome among calves with signs of bovine respiratory disease. 2011 J. Am. Vet. Med. Assoc. pmid:21718206
Han AR et al. Biosynthesis of glycosylated derivatives of tylosin in Streptomyces venezuelae. 2011 J. Microbiol. Biotechnol. pmid:21715968
Stead SL et al. Development and validation of a potentiometric biosensor assay for tylosin with demonstrated applicability for the detection of two other antimicrobial growth-promoter compounds in feedstuffs. 2011 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:21574083
Hidalgo Á et al. Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain. 2011 Antimicrob. Agents Chemother. pmid:21555771
Smee NM and Towell TL What is the evidence? Inflammatory bowel disease in a dog. 2011 J. Am. Vet. Med. Assoc. pmid:21529230
Bernal J et al. Determination of tylosins A, B, C and D in bee larvae by liquid chromatography coupled to ion trap-tandem mass spectrometry. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21498134
Kilpinen S et al. Effect of tylosin on dogs with suspected tylosin-responsive diarrhea: a placebo-controlled, randomized, double-blinded, prospective clinical trial. 2011 Acta Vet. Scand. pmid:21489311
Cacciapuoti AF et al. Microbiological and pharmacokinetic studies of acyl demycinosyltylosin and related tylosin derivatives. 1990 J. Antibiot. pmid:2145254
Zheng Y et al. Molecularly imprinted solid-phase extraction for determination of tilmicosin in feed using high performance liquid chromatography. 2011 Anal. Chim. Acta pmid:21435486
Ci X et al. Anti-inflammatory effects of tilmicosin in a noninfectious mouse model of allergic asthma. 2011 Immunopharmacol Immunotoxicol pmid:21428709
Cooprider KL et al. Feedlot efficiency implications on greenhouse gas emissions and sustainability. 2011 J. Anim. Sci. pmid:21398565
Juntunen P et al. Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. 2011 Vet. Microbiol. pmid:21397412
Kalmokoff M et al. Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. 2011 J. Appl. Microbiol. pmid:21395944
Lombardi KR et al. Pharmacokinetics of tilmicosin in beef cattle following intravenous and subcutaneous administration. 2011 J. Vet. Pharmacol. Ther. pmid:21323676
Kucerova Z et al. Antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolates from clinical outbreaks of porcine respiratory diseases. 2011 Vet. Microbiol. pmid:21316872
Alexander TW et al. Longitudinal characterization of antimicrobial resistance genes in feces shed from cattle fed different subtherapeutic antibiotics. 2011 BMC Microbiol. pmid:21261985
Ozaki H et al. Antimicrobial resistance in fecal Escherichia coli isolated from growing chickens on commercial broiler farms. 2011 Vet. Microbiol. pmid:21232883
Reynaldi FJ et al. [Binding of tylosin, tilmicosin and oxytetracycline to proteins from honeybees, larvae and beehive products]. 2010 Oct-Dec Rev. Argent. Microbiol. pmid:21229198
Song M et al. The controlled release of tilmicosin from silica nanoparticles. 2011 Drug Dev Ind Pharm pmid:21204738
Collington GK et al. The influence of inclusion of either an antibiotic or a probiotic in the diet on the development of digestive enzyme activity in the pig. 1990 Br. J. Nutr. pmid:2119223
Park JW et al. Generation of reduced macrolide analogs by regio-specific biotransformation. 2011 J. Antibiot. pmid:21102594
Kim EY et al. Pharmacokinetics of a florfenicol-tylosin combination after intravenous and intramuscular administration to beagle dogs. 2011 J. Vet. Med. Sci. pmid:21068517
Scott BA et al. Efficacy of tylosin tartrate on canine Staphylococcus intermedius isolates in vitro. 2010 Vet. Ther. pmid:20960412
Shimada T et al. Effects of the antimicrobial tylosin on the microbial community structure of an anaerobic sequencing batch reactor. 2011 Biotechnol. Bioeng. pmid:20830676
Mazzilli M and Zecconi A Assessment of epithelial cells' immune and inflammatory response to Staphylococcus aureus when exposed to a macrolide. 2010 J. Dairy Res. pmid:20822561
Muraina IA et al. Antimycoplasmal activity of some plant species from northern Nigeria compared to the currently used therapeutic agent. 2010 Pharm Biol pmid:20819025
Navashin SM et al. [Genetic and biochemical control of biosynthesis of macrolide antibiotics]. 1990 Antibiot. Khimioter. pmid:2078074
Stone JJ et al. Tylosin and chlortetracycline effects during swine manure digestion: influence of sodium azide. 2010 Bioresour. Technol. pmid:20728345
Guan S et al. Immunosuppressive activity of tilmicosin on the immune responses in mice. 2011 Immunopharmacol Immunotoxicol pmid:20718577
Juntunen P et al. Antimicrobial resistance in Campylobacter coli selected by tylosin treatment at a pig farm. 2010 Vet. Microbiol. pmid:20684867