Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Pyoderma D011711 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Campylobacter Infections D002169 13 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Liver Abscess D008100 6 associated lipids
Treponemal Infections D014211 3 associated lipids
Dysentery D004403 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Nguyen LT et al. The tylosin producer, Streptomyces fradiae, contains a second valine dehydrogenase. 1995 Microbiology (Reading, Engl.) pmid:7773408
Paesen J et al. Isolation of decomposition products of tylosin using liquid chromatography. 1995 J Chromatogr A pmid:7757214
Shryock TR et al. Proposed quality control guidelines for antimicrobial susceptibility tests using tilmicosin. 1995 J. Clin. Microbiol. pmid:7714188
Bobillot S et al. Chemical modification of tylosin. 1995 J. Antibiot. pmid:7649866
Creemer LC et al. Synthesis, antimicrobial activity and in vivo fluorine NMR of a hexafluorinated derivative of tilmicosin. 1995 J. Antibiot. pmid:7649867
Narandja A et al. 10,11,12,13-Tetrahydro derivatives of tylosin. II. Synthesis, antibacterial activity and tissue of 4'-deoxy-10,11,12,13-tetrahydrodesmycosin. 1995 J. Antibiot. pmid:7730160
Paesen J et al. Study of the stability of tylosin A in aqueous solutions. 1995 J Pharm Biomed Anal pmid:8573642
Ziv G et al. Disposition kinetics of tylosin tartrate administered intravenously and intramuscularly to normal and water-deprived camels. 1995 J. Vet. Pharmacol. Ther. pmid:8583543
Ziv G et al. Tilmicosin antibacterial activity and pharmacokinetics in cows. 1995 J. Vet. Pharmacol. Ther. pmid:8587151
Brown SA et al. Characterization of plasma and lung concentrations after ceftiofur sodium and tilmicosin phosphate administered subcutaneously to mice. 1995 J. Vet. Pharmacol. Ther. pmid:8587160
Blackall PJ et al. In-vitro antibacterial properties of tilmicosin against Australian isolates of Pasteurella multocida and Actinobacillus pleuropneumoniae from pigs. 1995 Aust. Vet. J. pmid:8787526
Kiehl DE and Kennington AS Analysis of tilmicosin in swine liver extracts by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry. 1995 Rapid Commun. Mass Spectrom. pmid:8527821
Galyean ML et al. Effects of arrival medication with tilmicosin phosphate on health and performance of newly received beef cattle. 1995 J. Anim. Sci. pmid:7665351
Scott PR Efficacy of strategic tilmicosin injection during an outbreak of respiratory disease in housed beef calves. 1995 Sep-Oct Br. Vet. J. pmid:8556318
Scott PR et al. Use of tilmicosin in a severe outbreak of respiratory disease in weaned beef calves. 1996 Aust. Vet. J. pmid:8660201
Wittum TE et al. Haptoglobin response to clinical respiratory tract disease in feedlot cattle. 1996 Am. J. Vet. Res. pmid:8723875
Musser J et al. Comparison of tilmicosin with long-acting oxytetracycline for treatment of respiratory tract disease in calves. 1996 J. Am. Vet. Med. Assoc. pmid:8682696
Fish SA and Cundliffe E Structure-activity studies of tylosin-related macrolides. 1996 J. Antibiot. pmid:8968399
Katoh T et al. The fractional inhibitory concentration index of antimicrobial agents for bacteria and Mycoplasma isolated from the nasal swabs of cattle with respiratory diseases. 1996 J. Vet. Med. Sci. pmid:8877979
Kuhstoss S et al. Production of a novel polyketide through the construction of a hybrid polyketide synthase. 1996 Gene pmid:8996112