Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Pyoderma D011711 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Campylobacter Infections D002169 13 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Liver Abscess D008100 6 associated lipids
Treponemal Infections D014211 3 associated lipids
Dysentery D004403 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Chopra S et al. Characterization of impurities in tylosin using dual liquid chromatography combined with ion trap mass spectrometry. 2013 Talanta pmid:23598092
Dinh QT et al. Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. 2011 Talanta pmid:21807177
Crown LA and Smith RB Accidental veterinary antibiotic injection into a farm worker. 1999 Tenn Med pmid:10474305
Doak GA Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. 2000 Theriogenology pmid:10990358
Kim S Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. 2000 Theriogenology pmid:10990359
Rosenbusch RF Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. 2000 Theriogenology pmid:10990360
Thomas CB Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. 2000 Theriogenology pmid:10990361
Visser IJ et al. Failure of antibiotics gentamycin, tylosin, lincomycin and spectinomycin to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. 1999 Theriogenology pmid:10728994
Boissevain I [Punishment after the fact]. 2007 Tijdschr Diergeneeskd pmid:17939495
Westerbeek JA and Jaartsveld FH [Mycoplasma infection on a cattle farm]. 1987 Tijdschr Diergeneeskd pmid:3603536
Westermarck E and Wiberg M Exocrine pancreatic insufficiency in the dog: historical background, diagnosis, and treatment. 2012 Top Companion Anim Med pmid:23148848
Devreese M et al. An in vitro model using the IPEC-J2 cell line for efficacy and drug interaction testing of mycotoxin detoxifying agents. 2013 Toxicol In Vitro pmid:23078954
Gershon P and Howells RE Synergy of four macrolide antibiotics with chloroquine against chloroquine-resistant Plasmodium falciparum in vitro. 1986 Trans. R. Soc. Trop. Med. Hyg. pmid:3299891
McGuigan MA Human exposures to tilmicosin (MICOTIL). 1994 Vet Hum Toxicol pmid:7975134
Jordan WH et al. A review of the toxicology of the antibiotic MICOTIL 300. 1993 Vet Hum Toxicol pmid:8470360
Donev B et al. [Intramammary drug forms of neotil in treating mastitis during lactation]. 1982 Vet Med Nauki pmid:7157656
Dilov P et al. [Comparative studies on the resorption, anti-anemic action and growth effect of FV-82 and dextrofer-100 on pigs]. 1984 Vet Med Nauki pmid:6474828
Dilov P et al. [Toxicity, tolerance and blood concentrations of iron and tylosin with the use of preparation FV-82]. 1983 Vet Med Nauki pmid:6623919
Donev B et al. [Toxicological studies of a combination of technical tylosin phosphate with bentonite (farmazin TB)]. 1983 Vet Med Nauki pmid:6659350
Hopper RJ and Miller ML Efficacy of swine erysipelas vaccine given simultaneously with medicated rations. 1981 Vet Med Small Anim Clin pmid:6916559
Hartman EG and Geryl J Comparison between the minimal inhibitory concentration of tilmicosin and oxytetracycline for bovine pneumonic Pasteurella haemolytica isolates. 1993 Vet Q pmid:8122359
Voeten AC and Litjens JB The hygienic treatment of turkey eggs by dipping in an antibiotic and disinfectant solution. 1982 Vet Q pmid:7112889
Nagaraja TG and Lechtenberg KF Liver abscesses in feedlot cattle. 2007 Vet. Clin. North Am. Food Anim. Pract. pmid:17606156
Barbour EK et al. Impact of synergism of calcium phosphomycin/tylosin tartarate supplements on the performance of broilers in the Lebanon. 2010 Jan-Mar Vet. Ital. pmid:20391366
Short CR Comparative pharmacokinetics--sorting the sheep from the goats. 1999 Vet. J. pmid:10558834
Taha AA et al. Disposition kinetics of tylosin administered intravenously and intramuscularly in desert sheep and Nubian goats. 1999 Vet. J. pmid:10558841
Fodor L et al. Efficacy evaluations of the use of oral tilmicosin in pneumonic calves. 2000 Vet. J. pmid:10712808
Montesissa C et al. Metabolism of tilmicosin by rabbit liver microsomes and hepatocytes. 2004 Vet. J. pmid:14623156
Teixeira AGV et al. Efficacy of tildipirosin metaphylaxis for the prevention of respiratory disease, otitis and mortality in pre-weaned Holstein calves. 2017 Vet. J. pmid:28093111
Kilpinen S et al. Oral tylosin administration is associated with an increase of faecal enterococci and lactic acid bacteria in dogs with tylosin-responsive diarrhoea. 2015 Vet. J. pmid:26049259
Devreese M et al. Interaction between tylosin and bentonite clay from a pharmacokinetic perspective. 2012 Vet. J. pmid:22749117
Mitchell JD et al. In vitro pharmacodynamics of gamithromycin against Mycoplasma mycoides subspecies mycoides Small Colony. 2013 Vet. J. pmid:23810743
Wang XF et al. Enhancement of antibacterial activity of tilmicosin against Staphylococcus aureus by solid lipid nanoparticles in vitro and in vivo. 2012 Vet. J. pmid:21900026
Marks SL and Kather EJ Antimicrobial susceptibilities of canine Clostridium difficile and Clostridium perfringens isolates to commonly utilized antimicrobial drugs. 2003 Vet. Microbiol. pmid:12742714
Tanner AC et al. Adaptation of the Sensititre broth microdilution technique to antimicrobial susceptibility testing of Mycoplasma hyopneumoniae. 1993 Vet. Microbiol. pmid:8273275
Reynaldi FJ et al. Effectiveness of tilmicosin against Paenibacillus larvae, the causal agent of American Foulbrood disease of honeybees. 2008 Vet. Microbiol. pmid:18539412
Marosevic D et al. In vivo spread of macrolide-lincosamide-streptogramin B (MLSB) resistance--a model study in chickens. 2014 Vet. Microbiol. pmid:24467930
Woolums AR et al. Multidrug resistant Mannheimia haemolytica isolated from high-risk beef stocker cattle after antimicrobial metaphylaxis and treatment for bovine respiratory disease. 2018 Vet. Microbiol. pmid:29981701
Juntunen P et al. Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. 2011 Vet. Microbiol. pmid:21397412
Blondeau JM et al. Comparative minimum inhibitory and mutant prevention drug concentrations of enrofloxacin, ceftiofur, florfenicol, tilmicosin and tulathromycin against bovine clinical isolates of Mannheimia haemolytica. 2012 Vet. Microbiol. pmid:22677482
Prats-van der Ham M et al. Molecular resistance mechanisms of Mycoplasma agalactiae to macrolides and lincomycin. 2017 Vet. Microbiol. pmid:29102109
Entorf M et al. Tylosin susceptibility of Staphylococci from bovine mastitis. 2014 Vet. Microbiol. pmid:24461550
Ozaki H et al. Antimicrobial resistance in fecal Escherichia coli isolated from growing chickens on commercial broiler farms. 2011 Vet. Microbiol. pmid:21232883
Lerner U et al. Acquired resistance to the 16-membered macrolides tylosin and tilmicosin by Mycoplasma bovis. 2014 Vet. Microbiol. pmid:24393633
Gautier-Bouchardon AV et al. In vitro development of resistance to enrofloxacin, erythromycin, tylosin, tiamulin and oxytetracycline in Mycoplasma gallisepticum, Mycoplasma iowae and Mycoplasma synoviae. 2002 Vet. Microbiol. pmid:12119137
Kucerova Z et al. Antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolates from clinical outbreaks of porcine respiratory diseases. 2011 Vet. Microbiol. pmid:21316872
Aarestrup FM and Friis NF Antimicrobial susceptibility testing of Mycoplasma hyosynoviae isolated from pigs during 1968 to 1971 and during 1995 and 1996. 1998 Vet. Microbiol. pmid:9646463
Shryock TR et al. Antimicrobial susceptibility of Moraxella bovis. 1998 Vet. Microbiol. pmid:9646479
Stipkovits L et al. In vitro testing of the anti-mycoplasma effect of some anti-coccidial drugs. 1987 Vet. Microbiol. pmid:3439016
Entorf M et al. Comparative erythromycin and tylosin susceptibility testing of streptococci from bovine mastitis. 2016 Vet. Microbiol. pmid:26732695