Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Pyoderma D011711 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Campylobacter Infections D002169 13 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Liver Abscess D008100 6 associated lipids
Treponemal Infections D014211 3 associated lipids
Dysentery D004403 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
De Liguoro M et al. Determination of tylosin residues in pig tissues using high-performance liquid chromatography. 1998 Analyst pmid:9764508
Ammida NH et al. Analysis of erythromycin and tylosin in bovine muscle using disposable screen printed electrodes. 2004 Analyst pmid:14737577
Martínez MF and Barth AD Early detection and treatment of vesicular adenitis in bulls. 2007 Anim. Reprod. Sci. pmid:17027202
Kawai K et al. Antimicrobial susceptibilities of Mycoplasma isolated from bovine mastitis in Japan. 2014 Anim. Sci. J. pmid:24261609
Berque I et al. [Stereoselective synthesis of biologically active macrolides. Total synthesis of tylosine]. 1998 Ann Pharm Fr pmid:9770007
Pai MP et al. Macrolide drug interactions: an update. 2000 Ann Pharmacother pmid:10772438
Mironov VA et al. [Effect of Ca2+ ions on biosynthesis and component composition of tylosin in Streptomyces fradiae]. 1997 Antibiot. Khimioter. pmid:9182505
Navashin SM et al. [Genetic and biochemical control of biosynthesis of macrolide antibiotics]. 1990 Antibiot. Khimioter. pmid:2078074
Tikhomirova LA et al. [Cytomorphological and cultural characteristics of tylosin-producing strains with different antibiotic activity]. 1991 Antibiot. Khimioter. pmid:1755702
MiliavskiÄ­ EB et al. [Electrophoretic separation of spores of producers of kanamycin and tylosin]. 1990 Antibiot. Khimioter. pmid:2334246
Panfilova ZI et al. [Obtaining of mutants of Streptomyces fradiae producing tylosin by action of nitrosomethylurea on synchronously germinating spores]. 1990 Antibiot. Khimioter. pmid:2383150
Esipov SE [Novel mathematical approach to determination of antibiotics concentration by agar diffusion method. Analysis of graphical, table and mathematical options of relative biological activity estimation]. 1998 Antibiot. Khimioter. pmid:9606490
Malanicheva IA et al. [Protoplast fusion in Streptomyces fradiae strains producing neomycin and tylosin]. 1992 Antibiot. Khimioter. pmid:1296531
Rodionova II et al. [Effect of protoplast formation on the antibiotic activity of the Streptomyces fradiae 165 strain--a producer of tylosin]. 1987 Antibiot. Med. Biotekhnol. pmid:2830838
Moubareck C et al. Multiple antibiotic resistance gene transfer from animal to human enterococci in the digestive tract of gnotobiotic mice. 2003 Antimicrob. Agents Chemother. pmid:12937011
Novotny GW et al. Ketolide antimicrobial activity persists after disruption of interactions with domain II of 23S rRNA. 2004 Antimicrob. Agents Chemother. pmid:15388419
Seno ET and Baltz RH Properties of S-adenosyl-L-methionine:macrocin O-methyltransferase in extracts of Streptomyces fradiae strains which produce normal or elevated levels of tylosin and in mutants blocked in specific O-methylations. 1981 Antimicrob. Agents Chemother. pmid:7305323
Achard A et al. Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. 2008 Antimicrob. Agents Chemother. pmid:18519724
Byrne-Bailey KG et al. Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. 2009 Antimicrob. Agents Chemother. pmid:19064898
Lin J et al. Effect of macrolide usage on emergence of erythromycin-resistant Campylobacter isolates in chickens. 2007 Antimicrob. Agents Chemother. pmid:17353243