Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Pyoderma D011711 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Campylobacter Infections D002169 13 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Liver Abscess D008100 6 associated lipids
Treponemal Infections D014211 3 associated lipids
Dysentery D004403 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Wardlaw AC et al. Bactericidal activity in the pig roundworm Ascaris suum. 1994 J. Appl. Bacteriol. pmid:8144403
Inouye M et al. Cloning and sequences of two macrolide-resistance-encoding genes from mycinamicin-producing Micromonospora griseorubida. 1994 Gene pmid:8163173
Scott PR Field study of undifferentiated respiratory disease in housed beef calves. 1994 Vet. Rec. pmid:8203107
Coronato S et al. A simple method to eliminate mycoplasma from cell cultures. 1994 J. Virol. Methods pmid:8175949
Tang L et al. Amino acid catabolism and antibiotic synthesis: valine is a source of precursors for macrolide biosynthesis in Streptomyces ambofaciens and Streptomyces fradiae. 1994 J. Bacteriol. pmid:7928973
Merson-Davies LA and Cundliffe E Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome. 1994 Mol. Microbiol. pmid:7984112
Inamoto T et al. Antibacterial activity of tilmicosin against Pasteurella multocida and Actinobacillus pleuropneumoniae isolated from pneumonic lesions in swine. 1994 J. Vet. Med. Sci. pmid:7865594
Caraffini S et al. Tylosin, an airborne contact allergen in veterinarians. 1994 Contact Derm. pmid:7867337
Lee SH and Lee KJ Kinetics of the repression of tylosin biosynthesis by ammonium ion in Streptomyces fradiae. 1994 J. Biotechnol. pmid:7764561
Danese P et al. Occupational contact dermatitis from tylosin. 1994 Contact Derm. pmid:8187499
Tan ZL et al. Serum neutralizing antibodies against Fusobacterium necrophorum leukotoxin in cattle with experimentally induced or naturally developed hepatic abscesses. 1994 J. Anim. Sci. pmid:8157537
Buller NB and Hampson DJ Antimicrobial susceptibility testing of Serpulina hyodysenteriae. 1994 Aust. Vet. J. pmid:7945100
Shryock TR et al. Effect of bentonite incorporated in a feed ration with tilmicosin in the prevention of induced Mycoplasma gallisepticum airsacculitis in broiler chickens. 1994 Jul-Sep Avian Dis. pmid:7832702
Chan W et al. Determination of tylosin and tilmicosin residues in animal tissues by reversed-phase liquid chromatography. 1994 Mar-Apr J AOAC Int pmid:8199468
Nguyen LT et al. The tylosin producer, Streptomyces fradiae, contains a second valine dehydrogenase. 1995 Microbiology (Reading, Engl.) pmid:7773408
Paesen J et al. Isolation of decomposition products of tylosin using liquid chromatography. 1995 J Chromatogr A pmid:7757214
Shryock TR et al. Proposed quality control guidelines for antimicrobial susceptibility tests using tilmicosin. 1995 J. Clin. Microbiol. pmid:7714188
Bobillot S et al. Chemical modification of tylosin. 1995 J. Antibiot. pmid:7649866
Creemer LC et al. Synthesis, antimicrobial activity and in vivo fluorine NMR of a hexafluorinated derivative of tilmicosin. 1995 J. Antibiot. pmid:7649867
Narandja A et al. 10,11,12,13-Tetrahydro derivatives of tylosin. II. Synthesis, antibacterial activity and tissue of 4'-deoxy-10,11,12,13-tetrahydrodesmycosin. 1995 J. Antibiot. pmid:7730160
Paesen J et al. Study of the stability of tylosin A in aqueous solutions. 1995 J Pharm Biomed Anal pmid:8573642
Ziv G et al. Disposition kinetics of tylosin tartrate administered intravenously and intramuscularly to normal and water-deprived camels. 1995 J. Vet. Pharmacol. Ther. pmid:8583543
Ziv G et al. Tilmicosin antibacterial activity and pharmacokinetics in cows. 1995 J. Vet. Pharmacol. Ther. pmid:8587151
Brown SA et al. Characterization of plasma and lung concentrations after ceftiofur sodium and tilmicosin phosphate administered subcutaneously to mice. 1995 J. Vet. Pharmacol. Ther. pmid:8587160
Blackall PJ et al. In-vitro antibacterial properties of tilmicosin against Australian isolates of Pasteurella multocida and Actinobacillus pleuropneumoniae from pigs. 1995 Aust. Vet. J. pmid:8787526
Tuomi ML and Räsänen L Contact allergy to tylosin and cobalt in a pig-farmer. 1995 Contact Derm. pmid:8654098
Lee SH and Lee KJ Threonine dehydratases in different strains of Streptomyces fradiae. 1995 J. Biotechnol. pmid:8562022
Kirchgessner M et al. [Effect of avilamycin and tylosin on the metabolizable energy in growing and finishing pigs]. 1995 Arch Tierernahr pmid:8526732
Kiehl DE and Kennington AS Analysis of tilmicosin in swine liver extracts by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry. 1995 Rapid Commun. Mass Spectrom. pmid:8527821
Harvey RB et al. Influence of the antibiotics lincomycin and tylosin on aflatoxicosis when added to aflatoxin-contaminated diets of growing swine. 1995 J. Vet. Diagn. Invest. pmid:7578454
Stock RA et al. Effect of monensin and monensin and tylosin combination on feed intake variation of feedlot steers. 1995 J. Anim. Sci. pmid:7601752
Zuzulova M et al. In vitro activity of tylosin and its derivatives against Ureaplasma urealyticum. 1995 Arzneimittelforschung pmid:8929244
Galyean ML et al. Effects of arrival medication with tilmicosin phosphate on health and performance of newly received beef cattle. 1995 J. Anim. Sci. pmid:7665351
Scott PR Efficacy of strategic tilmicosin injection during an outbreak of respiratory disease in housed beef calves. 1995 Sep-Oct Br. Vet. J. pmid:8556318
Moore GM et al. Efficacy dose determination study of tilmicosin phosphate in feed for control of pneumonia caused by Actinobacillus pleuropneumoniae in swine. 1996 Am. J. Vet. Res. pmid:8633812
Moore GM et al. Clinical field trials with tilmicosin phosphate in feed for the control of naturally acquired pneumonia caused by Actinobacillus pleuropneumoniae and Pasteurella multocida in swine. 1996 Am. J. Vet. Res. pmid:8633813
Day FG The value of tilmicosin in production medicine. 1996 J. Am. Vet. Med. Assoc. pmid:8617615
Solenberg PJ et al. Transposition mutagenesis in Streptomyces fradiae: identification of a neutral site for the stable insertion of DNA by transposon exchange. 1996 Gene pmid:8626067
Arisawa A et al. Direct fermentative production of acyltylosins by genetically-engineered strains of Streptomyces fradiae. 1996 J. Antibiot. pmid:8641997
Main BW et al. Cardiovascular effects of the macrolide antibiotic tilmicosin, administered alone and in combination with propranolol or dobutamine, in conscious unrestrained dogs. 1996 J. Vet. Pharmacol. Ther. pmid:8803881
Katoh T et al. The fractional inhibitory concentration index of antimicrobial agents for bacteria and Mycoplasma isolated from the nasal swabs of cattle with respiratory diseases. 1996 J. Vet. Med. Sci. pmid:8877979
Katoh T et al. Effect of a combination of antimicrobial agents for the treatment of respiratory disease in cattle. 1996 J. Vet. Med. Sci. pmid:8877980
McKay SG et al. Use of tilmicosin for treatment of pasteurellosis in rabbits. 1996 Am. J. Vet. Res. pmid:8836371
Shryock TR et al. Minimum inhibitory concentration breakpoints and disk diffusion inhibitory zone interpretive criteria for tilmicosin susceptibility testing against Pasteurella spp. associated with bovine respiratory disease. 1996 J. Vet. Diagn. Invest. pmid:8844577
Scott DW et al. Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. 1996 Can. Vet. J. pmid:8896878
Harvey RG Tylosin in the treatment of canine superficial pyoderma. 1996 Vet. Rec. pmid:8873399
Kobayashi H et al. Macrolide susceptibility of Mycoplasma hyorhinis isolated from piglets. 1996 Antimicrob. Agents Chemother. pmid:8849222
Kobayashi H et al. In vitro susceptibility of Mycoplasma hyosynoviae and M. hyorhinis to antimicrobial agents. 1996 J. Vet. Med. Sci. pmid:8959659
Molnár L Sensitivity of strains of Serpulina hyodysenteriae isolated in Hungary to chemotherapeutic drugs. 1996 Vet. Rec. pmid:8677605
Kuhstoss S et al. Production of a novel polyketide through the construction of a hybrid polyketide synthase. 1996 Gene pmid:8996112