Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Swine Diseases D013553 16 associated lipids
Tracheal Diseases D014133 3 associated lipids
Treponemal Infections D014211 3 associated lipids
Vasculitis D014657 14 associated lipids
Weight Gain D015430 101 associated lipids
Mycotoxicosis D015651 5 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Smith GW et al. Elimination kinetics of tilmicosin following intramammary administration in lactating dairy cattle. 2009 J. Am. Vet. Med. Assoc. pmid:19210246
Kouvela EC et al. Distinct mode of interaction of a novel ketolide antibiotic that displays enhanced antimicrobial activity. 2009 Antimicrob. Agents Chemother. pmid:19164155
Baggio A et al. Residues of antibacterial drugs in honey from the Italian market. 2009 Food Addit Contam Part B Surveill pmid:24784967
Chemier JA et al. Trends in microbial synthesis of natural products and biofuels. 2009 Adv. Enzymol. Relat. Areas Mol. Biol. pmid:18990830
Montgomery JL et al. Effects of dietary zilpaterol hydrochloride on feedlot performance and carcass characteristics of beef steers fed with and without monensin and tylosin. 2009 J. Anim. Sci. pmid:18997069
Boles JA et al. Growth implants reduced tenderness of steaks from steers and heifers with different genetic potentials for growth and marbling. 2009 J. Anim. Sci. pmid:18791138
Han C et al. Hydrogenated castor oil nanoparticles as carriers for the subcutaneous administration of tilmicosin: in vitro and in vivo studies. 2009 J. Vet. Pharmacol. Ther. pmid:19290940
Engi H [Perspectives of inhibition of multidrug resistance during cancer chemotherapy, in vitro and in vivo experiments]. 2009 Orv Hetil pmid:19293063
Hoese A et al. Chlortetracycline and tylosin runoff from soils treated with antimicrobial containing manure. 2009 J Environ Sci Health B pmid:19365753
Meyer NF et al. Effect of essential oils, tylosin, and monensin on finishing steer performance, carcass characteristics, liver abscesses, ruminal fermentation, and digestibility. 2009 J. Anim. Sci. pmid:19359504
Christodoulopoulos G Adverse outcome of using tilmicosin in a lamb with multiple ventricular septal defects. 2009 Can. Vet. J. pmid:19337615
Hu D and Coats JR Laboratory evaluation of mobility and sorption for the veterinary antibiotic, tylosin, in agricultural soils. 2009 J Environ Monit pmid:19724833
Khalifeh MS et al. Assessment of humoral and cellular-mediated immune response in chickens treated with tilmicosin, florfenicol, or enrofloxacin at the time of Newcastle disease vaccination. 2009 Poult. Sci. pmid:19762865
Guedes RM et al. Use of tylvalosin-medicated feed to control porcine proliferative enteropathy. 2009 Vet. Rec. pmid:19767637
Fitzgerald J Administration of micotil. 2009 Vet. Rec. pmid:19767643
Stone JJ et al. Effect of antimicrobial compounds tylosin and chlortetracycline during batch anaerobic swine manure digestion. 2009 Water Res. pmid:19695662
Atef M et al. Effect of albendazole administration on pharmacokinetic aspects of tylosin in lactating goats. 2009 Drug Metab Lett pmid:19702546
Hilton GG et al. Effects of feeding zilpaterol hydrochloride with and without monensin and tylosin on carcass cutability and meat palatability of beef steers. 2009 J. Anim. Sci. pmid:19028853
Byrne-Bailey KG et al. Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. 2009 Antimicrob. Agents Chemother. pmid:19064898
Petropoulos AD et al. Time-resolved binding of azithromycin to Escherichia coli ribosomes. 2009 J. Mol. Biol. pmid:19071138
Blackwell PA et al. Effects of agricultural conditions on the leaching behaviour of veterinary antibiotics in soils. 2009 Chemosphere pmid:19128817
Chénier MR and Juteau P Fate of chlortetracycline- and tylosin-resistant bacteria in an aerobic thermophilic sequencing batch reactor treating swine waste. 2009 Microb. Ecol. pmid:19125305
Liu F et al. Effects of six selected antibiotics on plant growth and soil microbial and enzymatic activities. 2009 Environ. Pollut. pmid:19157661
Bodoor K et al. Design and implementation of an ribonucleic acid (RNA) directed fragment library. 2009 J. Med. Chem. pmid:19445516
Hunter RP et al. Letter to the editor. 2009 Br. Poult. Sci. pmid:19904632
Suchodolski JS et al. The effect of the macrolide antibiotic tylosin on microbial diversity in the canine small intestine as demonstrated by massive parallel 16S rRNA gene sequencing. 2009 BMC Microbiol. pmid:19799792
Warner K et al. Control of Ornithobacterium rhinotracheale in poultry. 2009 Vet. Rec. pmid:19946131
Khaliq S et al. Change in colony morphology and kinetics of tylosin production after UV and gamma irradiation mutagenesis of Streptomyces fradiae NRRL-2702. 2009 Microbiol. Res. pmid:17475458
Sharma R et al. Selected antimicrobial resistance during composting of manure from cattle administered sub-therapeutic antimicrobials. 2009 Mar-Apr J. Environ. Qual. pmid:19202027
Granja R et al. Determination of erythromycin and tylosin residues in honey by LC/MS/MS. 2009 May-Jun J AOAC Int pmid:19610392
Juntunen P et al. Antimicrobial resistance in Campylobacter coli selected by tylosin treatment at a pig farm. 2010 Vet. Microbiol. pmid:20684867
Scott BA et al. Efficacy of tylosin tartrate on canine Staphylococcus intermedius isolates in vitro. 2010 Vet. Ther. pmid:20960412
Buret AG Immuno-modulation and anti-inflammatory benefits of antibiotics: the example of tilmicosin. 2010 Can. J. Vet. Res. pmid:20357951
Gallina G et al. Kinetics and intrapulmonary disposition of tilmicosin after single and repeated oral bolus administrations to rabbits. 2010 Vet. Res. Commun. pmid:20480234
van der Grinten E et al. Comparing the sensitivity of algal, cyanobacterial and bacterial bioassays to different groups of antibiotics. 2010 Chemosphere pmid:20430416
Cerdá RO et al. Impact of the type of catheter on the absorption of tylvalosin (acetylvaleryltylosin) administered orally to broiler chickens. 2010 J. Vet. Pharmacol. Ther. pmid:20444046
Shakya T and Wright GD Nucleotide selectivity of antibiotic kinases. 2010 Antimicrob. Agents Chemother. pmid:20231391
Liu YM et al. Sensitive determination of tilmicosin, erythromycin ethylsuccinate and clindamycin by CE with electrochemiluminescence detection using azithromycin as internal standard and its applications. 2010 J Sep Sci pmid:20235137
Catania S et al. Treatment of eggshell abnormalities and reduced egg production caused by Mycoplasma synoviae infection. 2010 Avian Dis. pmid:20608549
Alatrache A et al. Tylosin abatement in water by photocatalytic process. 2010 Water Sci. Technol. pmid:20651450
Kaizerman JA et al. Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines. 2010 Bioorg. Med. Chem. Lett. pmid:20594845
Peltier E et al. Zinc-induced antibiotic resistance in activated sludge bioreactors. 2010 Water Res. pmid:20537675
Logue CM et al. Repeated therapeutic dosing selects macrolide-resistant Campylobacter spp. in a turkey facility. 2010 J. Appl. Microbiol. pmid:20497488
Gyémánt N et al. In vitro and in vivo multidrug resistance reversal activity by a Betti-base derivative of tylosin. 2010 Br. J. Cancer pmid:20551959
Starosta AL et al. Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition. 2010 Chem. Biol. pmid:20534348
Paraud C et al. Evaluation of oral tilmicosin efficacy against severe cryptosporidiosis in neonatal kids under field conditions. 2010 Vet. Parasitol. pmid:20149542
Er A et al. Effects of tylosin on serum cytokine levels in healthy and lipopolysaccharide-treated mice. 2010 Acta Vet. Hung. pmid:20159741
Van Donkersgoed J et al. Drug residues recovered in feed after various feedlot mixer truck cleanout procedures. 2010 J. Food Prot. pmid:20051207
Lindemann MD et al. Evaluation of antibiotic effects on phosphorus digestibility and utilization by growing-finishing pigs fed a phosphorus-deficient, corn-soybean meal diet. 2010 J. Anim. Sci. pmid:20081078
Elkins CA et al. Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. 2010 Antimicrob. Agents Chemother. pmid:20038628