Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Swine Diseases D013553 16 associated lipids
Tracheal Diseases D014133 3 associated lipids
Treponemal Infections D014211 3 associated lipids
Vasculitis D014657 14 associated lipids
Weight Gain D015430 101 associated lipids
Mycotoxicosis D015651 5 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Cester CC et al. Effect of stage of oestrous cycle on tylosin disposition in genital tract secretions of cows. 1993 Res. Vet. Sci. pmid:8434145
Crepieux T et al. Randomized, non-inferiority trial comparing a nitric oxide releasing solution with a macrolide antibiotic for control of bovine respiratory disease in beef feedlot calves at high-risk of developing respiratory tract disease. 2016 Res. Vet. Sci. pmid:27033936
Ramadan A Pharmacokinetics of tilmicosin in serum and milk of goats. 1997 Jan-Feb Res. Vet. Sci. pmid:9160424
Goodwin RF In vitro activity of tiamulin against porcine mycoplasmas. 1985 Res. Vet. Sci. pmid:3975477
Reynaldi FJ et al. [Binding of tylosin, tilmicosin and oxytetracycline to proteins from honeybees, larvae and beehive products]. 2010 Oct-Dec Rev. Argent. Microbiol. pmid:21229198
Greer RT and Ryoo JP Development of ocular inserts for cattle. 1987 Scanning Microsc. pmid:3616580
Huwyler U et al. Efficacy evaluation of the use of oral tilmicosin in pneumonic calves. 1999 Schweiz. Arch. Tierheilkd. pmid:10228400
Xia X et al. Proteomic analysis of tylosin-resistant Mycoplasma gallisepticum reveals enzymatic activities associated with resistance. 2015 Sci Rep pmid:26584633
Brown K et al. Antimicrobial growth promoters modulate host responses in mice with a defined intestinal microbiota. 2016 Sci Rep pmid:27929072
Sura S et al. Transport of three veterinary antimicrobials from feedlot pens via simulated rainfall runoff. 2015 Sci. Total Environ. pmid:25839178
Luby EM et al. Fate and transport of tylosin-resistant bacteria and macrolide resistance genes in artificially drained agricultural fields receiving swine manure. 2016 Sci. Total Environ. pmid:26874610
Li Q et al. Co-addition of manure increases the dissipation rates of tylosin A and the numbers of resistance genes in laboratory incubation experiments. 2015 Sci. Total Environ. pmid:25958362
Ishikawa NK et al. Determination of tylosin excretion from sheep to assess tylosin spread to agricultural fields by manure application. 2018 Sci. Total Environ. pmid:29579651
Washington MT et al. Monitoring tylosin and sulfamethazine in a tile-drained agricultural watershed using polar organic chemical integrative sampler (POCIS). 2018 Sci. Total Environ. pmid:28854391
Srinivasan P et al. Sorption of selected veterinary antibiotics onto dairy farming soils of contrasting nature. 2014 Sci. Total Environ. pmid:24326064
Avci T and Elmas M Milk and blood pharmacokinetics of tylosin and tilmicosin following parenteral administrations to cows. 2014 ScientificWorldJournal pmid:25177733
Xie W et al. [Determination of five macrolide antibiotic residues in royal jelly samples by using high performance liquid chromatography tandem mass spectrometry]. 2007 Se Pu pmid:17679440
Horie M et al. [Determination of spiramycin and tilmicosin in meat and fish by LC/MS]. 2003 Shokuhin Eiseigaku Zasshi pmid:12968469
Fang XM et al. [A study on space mutation of Streptomyces fradiae]. 2005 Space Med Med Eng (Beijing) pmid:15977391
Dinh QT et al. Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. 2011 Talanta pmid:21807177