| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Foreign Bodies | D005547 | 5 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Erysipelothrix Infections | D004889 | 1 associated lipids |
| Enterotoxemia | D004767 | 1 associated lipids |
| Dysentery | D004403 | 4 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Conjunctivitis, Viral | D003236 | 1 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Clostridium Infections | D003015 | 5 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- FEMS Microbiol. Lett. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gotoh Y et al. | Chemical transformation of tylosin derivatives into neutral macrolides having a 3'-methoxyl group. | 1998 | Carbohydr. Res. | pmid:9720235 |
| Synek M et al. | [Immunologic aspects of macrolide antibiotics]. | 1989 | Cas. Lek. Cesk. | pmid:2731206 |
| Bébrová E et al. | [Immunologic reactivity of tylosin and erythromycin]. | 1989 | Cesk Epidemiol Mikrobiol Imunol | pmid:2790978 |
| Butler AR et al. | Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiae. | 1999 | Chem. Biol. | pmid:10322123 |
| Starosta AL et al. | Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition. | 2010 | Chem. Biol. | pmid:20534348 |
| Bate N et al. | Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae. | 1999 | Chem. Biol. | pmid:10467127 |
| Stratigopoulos G and Cundliffe E | Expression analysis of the tylosin-biosynthetic gene cluster: pivotal regulatory role of the tylQ product. | 2002 | Chem. Biol. | pmid:11841940 |
| De Liguoro M et al. | Use of oxytetracycline and tylosin in intensive calf farming: evaluation of transfer to manure and soil. | 2003 | Chemosphere | pmid:12729703 |
| Rabølle M and Spliid NH | Sorption and mobility of metronidazole, olaquindox, oxytetracycline and tylosin in soil. | 2000 | Chemosphere | pmid:10705549 |
| Baguer AJ et al. | Effects of the antibiotics oxytetracycline and tylosin on soil fauna. | 2000 | Chemosphere | pmid:10705553 |
| Loke ML et al. | Stability of Tylosin A in manure containing test systems determined by high performance liquid chromatography. | 2000 | Chemosphere | pmid:10705554 |
| Blackwell PA et al. | The dissipation and transport of veterinary antibiotics in a sandy loam soil. | 2007 | Chemosphere | pmid:17204303 |
| Guo X et al. | Sorption properties of tylosin on four different microplastics. | 2018 | Chemosphere | pmid:29933160 |
| Stromer BS et al. | Tylosin sorption to diatomaceous earth described by Langmuir isotherm and Freundlich isotherm models. | 2018 | Chemosphere | pmid:29874766 |
| Mitchell SM et al. | Hydrolysis of amphenicol and macrolide antibiotics: Chloramphenicol, florfenicol, spiramycin, and tylosin. | 2015 | Chemosphere | pmid:25618189 |
| Yin Y et al. | Iron and manganese oxides modified maize straw to remove tylosin from aqueous solutions. | 2018 | Chemosphere | pmid:29689529 |
| Zhang Q et al. | Sorption of tylosin on clay minerals. | 2013 | Chemosphere | pmid:24007614 |
| Halling-Sørensen B | Algal toxicity of antibacterial agents used in intensive farming. | 2000 | Chemosphere | pmid:10705551 |
| van der Grinten E et al. | Comparing the sensitivity of algal, cyanobacterial and bacterial bioassays to different groups of antibiotics. | 2010 | Chemosphere | pmid:20430416 |
| Loke ML et al. | Determination of the distribution coefficient (log Kd) of oxytetracycline, tylosin A, olaquindox and metronidazole in manure. | 2002 | Chemosphere | pmid:12146624 |