| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Foreign Bodies | D005547 | 5 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Erysipelothrix Infections | D004889 | 1 associated lipids |
| Enterotoxemia | D004767 | 1 associated lipids |
| Dysentery | D004403 | 4 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Conjunctivitis, Viral | D003236 | 1 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Clostridium Infections | D003015 | 5 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Appl. Environ. Microbiol. (2)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tuomi ML and Räsänen L | Contact allergy to tylosin and cobalt in a pig-farmer. | 1995 | Contact Derm. | pmid:8654098 |
| Caraffini S et al. | Tylosin, an airborne contact allergen in veterinarians. | 1994 | Contact Derm. | pmid:7867337 |
| Danese P et al. | Occupational contact dermatitis from tylosin. | 1994 | Contact Derm. | pmid:8187499 |
| Blackwood RS et al. | Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta). | 2008 | Comp. Med. | pmid:19793461 |
| Besserer F et al. | Tilmicosin toxicity: a case of accidental human tilmicosin injection managed with calcium, high-dose insulin and intravenous lipid emulsion therapy. | 2016 | Clin Toxicol (Phila) | pmid:27207720 |
| Grdisa M et al. | Effect of a 17-member azalide on tumor cell growth. | 1998 Sep-Oct | Chemotherapy | pmid:9732149 |
| De Liguoro M et al. | Use of oxytetracycline and tylosin in intensive calf farming: evaluation of transfer to manure and soil. | 2003 | Chemosphere | pmid:12729703 |
| Chen C et al. | Effect of composting and soil type on dissipation of veterinary antibiotics in land-applied manures. | 2018 | Chemosphere | pmid:29306199 |
| Kolz AC et al. | Sorption of tylosin onto swine manure. | 2005 | Chemosphere | pmid:15914248 |
| Rabølle M and Spliid NH | Sorption and mobility of metronidazole, olaquindox, oxytetracycline and tylosin in soil. | 2000 | Chemosphere | pmid:10705549 |
| Baguer AJ et al. | Effects of the antibiotics oxytetracycline and tylosin on soil fauna. | 2000 | Chemosphere | pmid:10705553 |
| Loke ML et al. | Stability of Tylosin A in manure containing test systems determined by high performance liquid chromatography. | 2000 | Chemosphere | pmid:10705554 |
| Hossain A et al. | Occurrence, distribution, ecological and resistance risks of antibiotics in surface water of finfish and shellfish aquaculture in Bangladesh. | 2017 | Chemosphere | pmid:28888121 |
| Blackwell PA et al. | The dissipation and transport of veterinary antibiotics in a sandy loam soil. | 2007 | Chemosphere | pmid:17204303 |
| Guo X et al. | Sorption properties of tylosin on four different microplastics. | 2018 | Chemosphere | pmid:29933160 |
| Stromer BS et al. | Tylosin sorption to diatomaceous earth described by Langmuir isotherm and Freundlich isotherm models. | 2018 | Chemosphere | pmid:29874766 |
| Mitchell SM et al. | Hydrolysis of amphenicol and macrolide antibiotics: Chloramphenicol, florfenicol, spiramycin, and tylosin. | 2015 | Chemosphere | pmid:25618189 |
| Yin Y et al. | Iron and manganese oxides modified maize straw to remove tylosin from aqueous solutions. | 2018 | Chemosphere | pmid:29689529 |
| Ali M et al. | Effect of redox potential and pH status on degradation and adsorption behavior of tylosin in dairy lagoon sediment suspension. | 2013 | Chemosphere | pmid:23352520 |
| Zhang Q et al. | Sorption of tylosin on clay minerals. | 2013 | Chemosphere | pmid:24007614 |
| Halling-Sørensen B | Algal toxicity of antibacterial agents used in intensive farming. | 2000 | Chemosphere | pmid:10705551 |
| Blackwell PA et al. | Effects of agricultural conditions on the leaching behaviour of veterinary antibiotics in soils. | 2009 | Chemosphere | pmid:19128817 |
| van der Grinten E et al. | Comparing the sensitivity of algal, cyanobacterial and bacterial bioassays to different groups of antibiotics. | 2010 | Chemosphere | pmid:20430416 |
| Loke ML et al. | Determination of the distribution coefficient (log Kd) of oxytetracycline, tylosin A, olaquindox and metronidazole in manure. | 2002 | Chemosphere | pmid:12146624 |
| Butler AR et al. | Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiae. | 1999 | Chem. Biol. | pmid:10322123 |
| Starosta AL et al. | Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition. | 2010 | Chem. Biol. | pmid:20534348 |
| Bate N et al. | Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae. | 1999 | Chem. Biol. | pmid:10467127 |
| Stratigopoulos G and Cundliffe E | Expression analysis of the tylosin-biosynthetic gene cluster: pivotal regulatory role of the tylQ product. | 2002 | Chem. Biol. | pmid:11841940 |
| Bébrová E et al. | [Immunologic reactivity of tylosin and erythromycin]. | 1989 | Cesk Epidemiol Mikrobiol Imunol | pmid:2790978 |
| Synek M et al. | [Immunologic aspects of macrolide antibiotics]. | 1989 | Cas. Lek. Cesk. | pmid:2731206 |
| Gotoh Y et al. | Chemical transformation of tylosin derivatives into neutral macrolides having a 3'-methoxyl group. | 1998 | Carbohydr. Res. | pmid:9720235 |
| Scott DW et al. | Efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. | 1994 | Can. Vet. J. | pmid:7994702 |
| Van Lunen TA | Growth performance of pigs fed diets with and without tylosin phosphate supplementation and reared in a biosecure all-in all-out housing system. | 2003 | Can. Vet. J. | pmid:12892287 |
| Croft A et al. | The effect of tilmicosin administered to ewes prior to lambing on incidence of clinical mastitis and subsequent lamb performance. | 2000 | Can. Vet. J. | pmid:10769768 |
| Van Donkersgoed J et al. | The effect of administering long-acting oxytetracycline and tilmicosin either by dart gun or by hand on injection site lesions and drug residues in beef cattle. | 1999 | Can. Vet. J. | pmid:12001341 |
| Schunich OC et al. | A comparison of prophylactic efficacy of tilmicosin and a new formulation of oxytetracycline in feedlot calves. | 2002 | Can. Vet. J. | pmid:12001501 |
| Abutarbush SM et al. | Comparison of enrofloxacin and ceftiofur sodium for the treatment of relapse of undifferentiated fever/bovine respiratory disease in feedlot cattle. | 2012 | Can. Vet. J. | pmid:22753964 |
| Scott DW et al. | Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. | 1996 | Can. Vet. J. | pmid:8896878 |
| Christodoulopoulos G | Adverse outcome of using tilmicosin in a lamb with multiple ventricular septal defects. | 2009 | Can. Vet. J. | pmid:19337615 |
| Hoar BR et al. | A comparison of the clinical field efficacy and safety of florfenicol and tilmicosin for the treatment of undifferentiated bovine respiratory disease of cattle in western Canada. | 1998 | Can. Vet. J. | pmid:9524721 |
| Barth AD and Wood MR | The effect of streptomycin, oxytetracycline, tilmicosin and phenylbutazone on spermatogenesis in bulls. | 1998 | Can. Vet. J. | pmid:10051958 |
| Jim GK et al. | A comparison of florfenicol and tilmicosin for the treatment of undifferentiated fever in feedlot calves in western Canada. | 1999 | Can. Vet. J. | pmid:10086218 |
| Paradis MA et al. | Efficacy of tilmicosin in the control of experimentally induced Actinobacillus pleuropneumoniae infection in swine. | 2004 | Can. J. Vet. Res. | pmid:14979429 |
| Fittipaldi N et al. | Assessment of the efficacy of tilmicosin phosphate to eliminate Actinobacillus pleuropneumoniae from carrier pigs. | 2005 | Can. J. Vet. Res. | pmid:15971680 |
| Goubau S et al. | Tilmicosin does not inhibit interleukin-8 gene expression in the bovine lung experimentally infected with Mannheimia (Pasteurella) haemolytica. | 2000 | Can. J. Vet. Res. | pmid:11041503 |
| Dingwell RT et al. | Influence of the genotype of Staphylococcus aureus, determined by pulsed-field gel electrophoresis, on dry-period elimination of subclinical mastitis in Canadian dairy herds. | 2006 | Can. J. Vet. Res. | pmid:16639943 |
| Brumbaugh GW et al. | Susceptibility of Mycobacterium avium sbsp paratuberculosis to monensin sodium or tilmicosin phosphate in vitro and resulting infectivity in a murine model. | 2004 | Can. J. Vet. Res. | pmid:15352541 |
| Morck DW et al. | Treatment of experimentally induced pneumonic pasteurellosis of young calves with tilmicosin. | 1997 | Can. J. Vet. Res. | pmid:9242998 |
| Buret AG | Immuno-modulation and anti-inflammatory benefits of antibiotics: the example of tilmicosin. | 2010 | Can. J. Vet. Res. | pmid:20357951 |
| Burrows GE et al. | Antibiotic disposition in experimental pneumonic pasteurellosis: gentamicin and tylosin. | 1986 | Can. J. Vet. Res. | pmid:3756673 |