Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Foreign Bodies D005547 5 associated lipids
Facial Dermatoses D005148 7 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Enterotoxemia D004767 1 associated lipids
Dysentery D004403 4 associated lipids
Diarrhea D003967 32 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Colitis D003092 69 associated lipids
Clostridium Infections D003015 5 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Brown K et al. Antimicrobial growth promoters modulate host responses in mice with a defined intestinal microbiota. 2016 Sci Rep pmid:27929072
Canning P et al. Concentrations of tylvalosin and 3-O-acetyltylosin attained in the synovial fluid of swine after administration by oral gavage at 50 and 5 mg/kg. 2016 J. Vet. Pharmacol. Ther. pmid:27086612
Mendoza J et al. Concentrations of tilmicosin in mammary gland secretions of dairy cows following subcutaneous administration of one or two doses of an experimental preparation of tilmicosin and its efficacy against intramammary infections caused by Staphylococcus aureus. 2016 Am. J. Vet. Res. pmid:27580103
El-Ela FI et al. Investigating the potential role of vitamin E in modulating the immunosuppressive effects of tylvalosin and florfenicol in broiler chickens. 2016 Res. Vet. Sci. pmid:27663366
Amarakoon ID et al. Dissipation of Antimicrobials in Feedlot Manure Compost after Oral Administration versus Fortification after Excretion. 2016 J. Environ. Qual. pmid:27065397
García-Sánchez L et al. Tylosin effect on methanogenesis in an anaerobic biomass from swine wastewater treatment. 2016 Water Sci. Technol. pmid:26819401
Xia X et al. Proteomic analysis of tylosin-resistant Mycoplasma gallisepticum reveals enzymatic activities associated with resistance. 2015 Sci Rep pmid:26584633
Lu C et al. Identification of novel tylosin analogues generated by a wblA disruption mutant of Streptomyces ansochromogenes. 2015 Microb. Cell Fact. pmid:26525981
Nobel YR et al. Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment. 2015 Nat Commun pmid:26123276
Maxwell CL et al. The effects of technology use in feedlot production systems on feedlot performance and carcass characteristics. 2015 J. Anim. Sci. pmid:26020911
Amachawadi RG et al. Effects of In-Feed Copper, Chlortetracycline, and Tylosin on the Prevalence of Transferable Copper Resistance Gene, tcrB, Among Fecal Enterococci of Weaned Piglets. 2015 Foodborne Pathog. Dis. pmid:26258261
Sura S et al. Transport of three veterinary antimicrobials from feedlot pens via simulated rainfall runoff. 2015 Sci. Total Environ. pmid:25839178
Sehati N et al. Application of hollow fiber membrane mediated with titanium dioxide nanowire/reduced graphene oxide nanocomposite in preconcentration of clotrimazole and tylosin. 2015 J Chromatogr A pmid:26477522
Blondeau JM et al. Bactericidal effects of various concentrations of enrofloxacin, florfenicol, tilmicosin phosphate, and tulathromycin on clinical isolates of Mannheimia haemolytica. 2015 Am. J. Vet. Res. pmid:26413823
Hao H et al. Microbiological toxicity of tilmicosin on human colonic microflora in chemostats. 2015 Regul. Toxicol. Pharmacol. pmid:26190303
Kilpinen S et al. Oral tylosin administration is associated with an increase of faecal enterococci and lactic acid bacteria in dogs with tylosin-responsive diarrhoea. 2015 Vet. J. pmid:26049259
Whitehead TR et al. Savagea faecisuis gen. nov., sp. nov., a tylosin- and tetracycline-resistant bacterium isolated from a swine-manure storage pit. 2015 Antonie Van Leeuwenhoek pmid:25980832
Li Q et al. Co-addition of manure increases the dissipation rates of tylosin A and the numbers of resistance genes in laboratory incubation experiments. 2015 Sci. Total Environ. pmid:25958362
Le T et al. A quantum dot-based immunoassay for screening of tylosin and tilmicosin in edible animal tissues. 2015 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:25822697
Zhu H et al. Immobilization of Streptomyces thermotolerans 11432 on polyurethane foam to improve production of acetylisovaleryltylosin. 2015 J. Ind. Microbiol. Biotechnol. pmid:25413211