Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Foreign Bodies D005547 5 associated lipids
Facial Dermatoses D005148 7 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Enterotoxemia D004767 1 associated lipids
Dysentery D004403 4 associated lipids
Diarrhea D003967 32 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Colitis D003092 69 associated lipids
Clostridium Infections D003015 5 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Sassman SA et al. Sorption of tylosin A, D, and A-aldol and degradation of tylosin A in soils. 2007 Environ. Toxicol. Chem. pmid:17702335
Ladely SR et al. Development of macrolide-resistant Campylobacter in broilers administered subtherapeutic or therapeutic concentrations of tylosin. 2007 J. Food Prot. pmid:17803155
Martínez MF and Barth AD Early detection and treatment of vesicular adenitis in bulls. 2007 Anim. Reprod. Sci. pmid:17027202
González de la Huebra MJ et al. Sample preparation strategy for the simultaneous determination of macrolide antibiotics in animal feedingstuffs by liquid chromatography with electrochemical detection (HPLC-ECD). 2007 J Pharm Biomed Anal pmid:17257795
Kart A et al. The possible protective effect of L-carnitine on tilmicosin-induced cardiotoxicity in mice. 2007 J Vet Med A Physiol Pathol Clin Med pmid:17381679
Lin J et al. Effect of macrolide usage on emergence of erythromycin-resistant Campylobacter isolates in chickens. 2007 Antimicrob. Agents Chemother. pmid:17353243
Litterio NJ et al. Microbiological screening test validation for detection of tylosin excretion in milk of cows with low and high somatic cell counts. 2007 J Vet Med A Physiol Pathol Clin Med pmid:17359452
Allaire SE et al. Sorption kinetics of chlortetracyline and tylosin on sandy loam and heavy clay soils. 2006 Jul-Aug J. Environ. Qual. pmid:16738380
Fu H et al. Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides. 2006 Bioorg. Med. Chem. Lett. pmid:16343900
Chelliapan S et al. Performance of an up-flow anaerobic stage reactor (UASR) in the treatment of pharmaceutical wastewater containing macrolide antibiotics. 2006 Water Res. pmid:16387347
Peng Z and Bang-Ce Y Small molecule microarrays for drug residue detection in foodstuffs. 2006 J. Agric. Food Chem. pmid:16968051
DiLorenzo N et al. Effects of feeding polyclonal antibody preparations on ruminal bacterial populations and ruminal pH of steers fed high-grain diets. 2006 J. Anim. Sci. pmid:16864880
McAllister TA et al. Shedding of escherichia coli O157:H7 by cattle fed diets containing monensin or tylosin. 2006 J. Food Prot. pmid:16995508
Industry guidance on the administration of tilmicosin. 2006 Vet. Rec. pmid:16924727
Bate N et al. Regulation of tylosin biosynthesis involving 'SARP-helper' activity. 2006 Mol. Microbiol. pmid:16942604
Jacobsen AM and Halling-Sørensen B Multi-component analysis of tetracyclines, sulfonamides and tylosin in swine manure by liquid chromatography-tandem mass spectrometry. 2006 Anal Bioanal Chem pmid:16485090
Jung WS et al. Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae. 2006 Appl. Microbiol. Biotechnol. pmid:16493552
Carlson JC and Mabury SA Dissipation kinetics and mobility of chlortetracycline, tylosin, and monensin in an agricultural soil in Northumberland County, Ontario, Canada. 2006 Environ. Toxicol. Chem. pmid:16494218
Womble A et al. Pulmonary disposition of tilmicosin in foals and in vitro activity against Rhodococcus equi and other common equine bacterial pathogens. 2006 J. Vet. Pharmacol. Ther. pmid:17083461
Booker CW et al. An evaluation of the metaphylactic effect of ceftiofur crystalline free Acid in feedlot calves. 2006 Vet. Ther. pmid:17039449
Karahalios P et al. On the mechanism of action of 9-O-arylalkyloxime derivatives of 6-O-mycaminosyltylonolide, a new class of 16-membered macrolide antibiotics. 2006 Mol. Pharmacol. pmid:16873579
Hamscher G et al. Quantitative analysis of tylosin in eggs by high performance liquid chromatography with electrospray ionization tandem mass spectrometry: residue depletion kinetics after administration via feed and drinking water in laying hens. 2006 J. Agric. Food Chem. pmid:17117786
Veenhuizen MF et al. Analysis of reports of human exposure to Micotil 300 (tilmicosin injection). 2006 J. Am. Vet. Med. Assoc. pmid:17144818
Couper A et al. Treatment of pneumonia in pigs with long-acting injectable tylosin. 2006 Vet. Rec. pmid:17158711
Chun S et al. Influence of agricultural antibiotics and 17beta-estradiol on the microbial community of soil. 2006 J Environ Sci Health B pmid:16893780
Nozal Nalda MJ et al. Trace analysis of antibacterial tylosin A, B, C and D in honey by liquid chromatography-electrospray ionization-mass spectrometry. 2006 J Sep Sci pmid:16544883
Cao XY et al. Tilmicosin and tylosin have anti-inflammatory properties via modulation of COX-2 and iNOS gene expression and production of cytokines in LPS-induced macrophages and monocytes. 2006 Int. J. Antimicrob. Agents pmid:16647840
Dingwell RT et al. Influence of the genotype of Staphylococcus aureus, determined by pulsed-field gel electrophoresis, on dry-period elimination of subclinical mastitis in Canadian dairy herds. 2006 Can. J. Vet. Res. pmid:16639943
ter Laak TL et al. The effect of pH and ionic strength on the sorption of sulfachloropyridazine, tylosin, and oxytetracycline to soil. 2006 Environ. Toxicol. Chem. pmid:16629129
ter Laak TL et al. Estimation of soil sorption coefficients of veterinary pharmaceuticals from soil properties. 2006 Environ. Toxicol. Chem. pmid:16629132
Terui Y et al. Synthesis of 2-methyl 16-membered macrolide derived from tylosin. 2006 J. Antibiot. pmid:16629410
Jiang H et al. Residue depletion of tilmicosin in cattle after subcutaneous administration. 2006 J. Agric. Food Chem. pmid:16819937
Yang S et al. Trace analysis and occurrence of anhydroerythromycin and tylosin in influent and effluent wastewater by liquid chromatography combined with electrospray tandem mass spectrometry. 2006 Anal Bioanal Chem pmid:16715282
García-Mayor MA et al. Liquid chromatography-UV diode-array detection method for multi-residue determination of macrolide antibiotics in sheep's milk. 2006 J Chromatogr A pmid:16682049
Shakeri-Nejad K and Stahlmann R Drug interactions during therapy with three major groups of antimicrobial agents. 2006 Expert Opin Pharmacother pmid:16556082
Pringle M et al. Tiamulin resistance in porcine Brachyspira pilosicoli isolates. 2006 Res. Vet. Sci. pmid:16253666
Kim D et al. In vitro susceptibilities of Leptospira spp. and Borrelia burgdorferi isolates to amoxicillin, tilmicosin, and enrofloxacin. 2006 J. Vet. Sci. pmid:17106227
Westermarck E et al. Effect of diet and tylosin on chronic diarrhea in beagles. 2005 Nov-Dec J. Vet. Intern. Med. pmid:16355675
Chander Y et al. Antibacterial activity of soil-bound antibiotics. 2005 Nov-Dec J. Environ. Qual. pmid:16221813
Kumar K et al. Antibiotic uptake by plants from soil fertilized with animal manure. 2005 Nov-Dec J. Environ. Qual. pmid:16221828
Westermarck E et al. Tylosin-responsive chronic diarrhea in dogs. 2005 Mar-Apr J. Vet. Intern. Med. pmid:15822561
Liutskanova DG et al. [Increase in tylosin production by a commercial strain of Streptomyces fradiae]. 2005 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:15859462
Kolz AC et al. Degradation and metabolite production of tylosin in anaerobic and aerobic swine-manure lagoons. 2005 Jan-Feb Water Environ. Res. pmid:15765935
Rooklidge SJ et al. Modeling antimicrobial contaminant removal in slow sand filtration. 2005 Jan-Feb Water Res. pmid:15644241
Menozzi A et al. Effect of the macrolide antibacterial drug, tylosin, on TNBS-induced colitis in the rat. 2005 Pharmacology pmid:15756055
Pfister P et al. 23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A-->G. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15795375
Godinho KS et al. Efficacy of tulathromycin in the treatment and prevention of natural outbreaks of bovine respiratory disease in European cattle. 2005 Vet. Ther. pmid:16094560
Kilgore WR et al. Clinical effectiveness of tulathromycin, a novel triamilide antimicrobial, for the control of respiratory disease in cattle at high risk for developing bovine respiratory disease. 2005 Vet. Ther. pmid:16094561
Kilgore WR et al. Therapeutic efficacy of tulathromycin, a novel triamilide antimicrobial, against bovine respiratory disease in feeder calves. 2005 Vet. Ther. pmid:16094562
Rooney KA et al. Efficacy of tulathromycin compared with tilmicosin and florfenicol for the control of respiratory disease in cattle at high risk of developing bovine respiratory disease. 2005 Vet. Ther. pmid:16094563