Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Foreign Bodies D005547 5 associated lipids
Facial Dermatoses D005148 7 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Enterotoxemia D004767 1 associated lipids
Dysentery D004403 4 associated lipids
Diarrhea D003967 32 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Colitis D003092 69 associated lipids
Clostridium Infections D003015 5 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Lu L et al. Autoinducer 2-like activity in poultry-associated enteric bacteria in response to subtherapeutic antibiotic exposure. 2005 Avian Dis. pmid:15839416
Loftin KA et al. Inhibition of microbial metabolism in anaerobic lagoons by selected sulfonamides, tetracyclines, lincomycin, and tylosin tartrate. 2005 Environ. Toxicol. Chem. pmid:15839550
Halling-Sørensen B et al. Dissipation and effects of chlortetracycline and tylosin in two agricultural soils: a field-scale study in southern Denmark. 2005 Environ. Toxicol. Chem. pmid:15839553
Wang J et al. Determination of five macrolide antibiotic residues in eggs using liquid chromatography/electrospray ionization tandem mass spectrometry. 2005 J. Agric. Food Chem. pmid:15769104
Blackwell PA et al. Evaluation of a lower tier exposure assessment model for veterinary medicines. 2005 J. Agric. Food Chem. pmid:15769156
Kay P et al. A lysimeter experiment to investigate the leaching of veterinary antibiotics through a clay soil and comparison with field data. 2005 Environ. Pollut. pmid:15589660
Thompson TS et al. Determination of lincomycin and tylosin residues in honey by liquid chromatography/tandem mass spectrometry. 2005 Rapid Commun. Mass Spectrom. pmid:15645470
Beier RC et al. Production and characterization of monoclonal antibodies against the antibiotic tilmicosin. 2005 J. Agric. Food Chem. pmid:16332115
Rozeboom DW et al. Effects of mannan oligosaccharide and an antimicrobial product in nursery diets on performance of pigs reared on three different farms. 2005 J. Anim. Sci. pmid:16230663
Jensen LB and Aarestrup FM Regulation of the erm(C) gene in Staphylococci from reservoir with different usage of macrolides. 2005 Acta Vet. Scand. pmid:16261929
Ayling RD et al. Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection. 2005 Antimicrob. Agents Chemother. pmid:16304194
Brain RA et al. Aquatic microcosm assessment of the effects of tylosin on Lemna gibba and Myriophyllum spicatum. 2005 Environ. Pollut. pmid:15519715
Nutsch RG et al. Comparative efficacy of tulathromycin, tilmicosin, and florfenicol in the treatment of bovine respiratory disease in stocker cattle. 2005 Vet. Ther. pmid:16094564
Skogerboe TL et al. Comparative efficacy of tulathromycin versus florfenicol and tilmicosin against undifferentiated bovine respiratory disease in feedlot cattle. 2005 Vet. Ther. pmid:16094565
Patterson J et al. Selected culturable enteric bacterial populations are modified by diet acidification and the growth promotant Tylosin. 2005 Lett. Appl. Microbiol. pmid:16033507
Kolz AC et al. Sorption of tylosin onto swine manure. 2005 Chemosphere pmid:15914248
Yong H et al. Design, synthesis and structure-activity relationships of 6-O-arylpropargyl diazalides with potent activity against multidrug-resistant Streptococcus pneumoniae. 2005 Bioorg. Med. Chem. Lett. pmid:15863336
Vicca J et al. Efficacy of in-feed medication with tylosin for the treatment and control of Mycoplasma hyopneumoniae infections. 2005 Vet. Rec. pmid:15879541
Fittipaldi N et al. Assessment of the efficacy of tilmicosin phosphate to eliminate Actinobacillus pleuropneumoniae from carrier pigs. 2005 Can. J. Vet. Res. pmid:15971680
Fang XM et al. [A study on space mutation of Streptomyces fradiae]. 2005 Space Med Med Eng (Beijing) pmid:15977391
Alippi AM et al. In vitro and in vivo susceptibility of the honeybee bacterial pathogen Paenibacillus larvae subsp. larvae to the antibiotic tylosin. 2005 Vet. Microbiol. pmid:15951140
Wu CM et al. Induction of macrolide resistance in Mycoplasma gallisepticum in vitro and its resistance-related mutations within domain V of 23S rRNA. 2005 FEMS Microbiol. Lett. pmid:15936901
Forrester MB Human exposures to tilmicosin reported to poison centres, Texas, 1998-2003. 2005 Hum Exp Toxicol pmid:16004193
Shen J et al. Pharmacokinetics of tilmicosin after oral administration in swine. 2005 Am. J. Vet. Res. pmid:16008233
Caldow M et al. Development and validation of an optical SPR biosensor assay for tylosin residues in honey. 2005 J. Agric. Food Chem. pmid:16159159
Chun S et al. Effect of agricultural antibiotics on the persistence and transformation of 17beta-estradiol in a Sequatchie loam. 2005 J Environ Sci Health B pmid:16190018
Clay SA et al. Tylosin sorption to silty clay loam soils, swine manure, and sand. 2005 J Environ Sci Health B pmid:16194921
Gramse MJ et al. Determination of tylosin in feeds by liquid chromatography with solid-phase extraction. 2004 Mar-Apr J AOAC Int pmid:15164825
Lee WD et al. Tilmicosin-induced bovine neutrophil apoptosis is cell-specific and downregulates spontaneous LTB4 synthesis without increasing Fas expression. 2004 Mar-Apr Vet. Res. pmid:15099497
Yildiz S et al. Tylosin does not affect GnRH-induced LH secretion in rams. 2004 Jan-Feb Reprod. Toxicol. pmid:15013072
Dykman LA et al. [Immunogenic properties of the colloidal gold]. 2004 Jan-Feb Izv. Akad. Nauk. Ser. Biol. pmid:15049073
Kumar K et al. Enzyme-linked immunosorbent assay for ultratrace determination of antibiotics in aqueous samples. 2004 Jan-Feb J. Environ. Qual. pmid:14964379
Mathers JJ et al. Inhibition of resistance plasmid transfer in Escherichia coli by ionophores, chlortetracycline, bacitracin, and ionophore/antimicrobial combinations. 2004 Apr-Jun Avian Dis. pmid:15283418
Stratigopoulos G et al. Positive control of tylosin biosynthesis: pivotal role of TylR. 2004 Mol. Microbiol. pmid:15554972
Taniguchi K et al. The role of histidine residues conserved in the putative ATP-binding region of macrolide 2'-phosphotransferase II. 2004 FEMS Microbiol. Lett. pmid:15033229
Paradis MA et al. Efficacy of tilmicosin in the control of experimentally induced Actinobacillus pleuropneumoniae infection in swine. 2004 Can. J. Vet. Res. pmid:14979429
Montesissa C et al. Metabolism of tilmicosin by rabbit liver microsomes and hepatocytes. 2004 Vet. J. pmid:14623156
Mutak S et al. Semisynthetic macrolide antibacterials derived from tylosin. Synthesis and structure-activity relationships of novel desmycosin analogues. 2004 J. Med. Chem. pmid:14711312
Kay P et al. Fate of veterinary antibiotics in a macroporous tile drained clay soil. 2004 Environ. Toxicol. Chem. pmid:15180364
Pettis JS et al. Larval Apis mellifera L. (Hymenoptera: Apidae) mortality after topical application of antibiotics and dusts. 2004 J. Econ. Entomol. pmid:15154433
Chirase NK et al. Effect of simulated ambient particulate matter exposure on performance, rectal temperature, and leukocytosis of young Spanish goats with or without tilmicosin phosphate. 2004 J. Anim. Sci. pmid:15080345
Fajt VR et al. Effect of danofloxacin and tilmicosin on body temperatures of beef calves with pneumonia experimentally induced by inoculation with Mannheimia haemolytica. 2004 Am. J. Vet. Res. pmid:15141881
Van Poucke C et al. Tylosin detection in animal feed by liquid chromatography-tandem mass spectrometry with enzymatic hydrolysis of the tylosin urea adduct. 2004 J. Agric. Food Chem. pmid:15137817
Cusack PM Effect of mass medication with antibiotics at feedlot entry on the health and growth rate of cattle destined for the Australian domestic market. 2004 Aust. Vet. J. pmid:15088981
Zhang Y et al. Residue depletion of tilmicosin in chicken tissues. 2004 J. Agric. Food Chem. pmid:15113165
Wang J Determination of five macrolide antibiotic residues in honey by LC-ESI-MS and LC-ESI-MS/MS. 2004 J. Agric. Food Chem. pmid:14733491
Moretto A et al. Slow release of two antibiotics of veterinary interest from PVA hydrogels. 2004 Farmaco pmid:14751309
Ammida NH et al. Analysis of erythromycin and tylosin in bovine muscle using disposable screen printed electrodes. 2004 Analyst pmid:14737577
Karlsson M et al. Further characterization of porcine Brachyspira hyodysenteriae isolates with decreased susceptibility to tiamulin. 2004 J. Med. Microbiol. pmid:15017283
Rowan TG et al. Efficacy of danofloxacin in the treatment of respiratory disease in European cattle. 2004 Vet. Rec. pmid:15160844