Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Mycotoxicosis D015651 5 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Tracheal Diseases D014133 3 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Mironov VA et al. [Effect of Ca2+ ions on biosynthesis and component composition of tylosin in Streptomyces fradiae]. 1997 Antibiot. Khimioter. pmid:9182505
Navashin SM et al. [Genetic and biochemical control of biosynthesis of macrolide antibiotics]. 1990 Antibiot. Khimioter. pmid:2078074
Malanicheva IA et al. [Protoplast fusion in Streptomyces fradiae strains producing neomycin and tylosin]. 1992 Antibiot. Khimioter. pmid:1296531
Rodionova II et al. [Effect of protoplast formation on the antibiotic activity of the Streptomyces fradiae 165 strain--a producer of tylosin]. 1987 Antibiot. Med. Biotekhnol. pmid:2830838
Chin AC et al. Tilmicosin induces apoptosis in bovine peripheral neutrophils in the presence or in the absence of Pasteurella haemolytica and promotes neutrophil phagocytosis by macrophages. 2000 Antimicrob. Agents Chemother. pmid:10952596
Jost BH et al. Tylosin resistance in Arcanobacterium pyogenes is encoded by an erm X determinant. 2003 Antimicrob. Agents Chemother. pmid:14576111
Elkins CA and Mullis LB Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. 2007 Antimicrob. Agents Chemother. pmid:17210767
Memili E and Weisblum B Essential role of endogenously synthesized tylosin for induction of ermSF in Streptomyces fradiae. 1997 Antimicrob. Agents Chemother. pmid:9145902
Robredo B et al. From vanA Enterococcus hirae to vanA Enterococcus faecium: a study of feed supplementation with avoparcin and tylosin in young chickens. 1999 Antimicrob. Agents Chemother. pmid:10223926
Huber ML et al. Branched-chain fatty acids produced by mutants of Streptomyces fradiae, putative precursors of the lactone ring of tylosin. 1990 Antimicrob. Agents Chemother. pmid:2221862