Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Mycotoxicosis D015651 5 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Tracheal Diseases D014133 3 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Lüthje P and Schwarz S Molecular analysis of constitutively expressed erm(C) genes selected in vitro in the presence of the non-inducers pirlimycin, spiramycin and tylosin. 2007 J. Antimicrob. Chemother. pmid:17085767
Szczepanowski R et al. Novel macrolide resistance module carried by the IncP-1beta resistance plasmid pRSB111, isolated from a wastewater treatment plant. 2007 Antimicrob. Agents Chemother. pmid:17101677
Vincent U et al. Validation of an analytical method for the determination of spiramycin, virginiamycin and tylosin in feeding-stuffs by thin-layer chromatography and bio-autography. 2007 Food Addit Contam pmid:17454108
Berrang ME et al. Subtherapeutic tylosin phosphate in broiler feed affects Campylobacter on carcasses during processing. 2007 Poult. Sci. pmid:17495097
Herrera M et al. Quantitative determination of tilmicosin in canine serum by high performance liquid chromatography-tandem mass spectrometry. 2007 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:17627909
Korshunova GA et al. [Peptide derivatives of tylosin-related macrolides]. 2007 Mar-Apr Bioorg. Khim. pmid:17476984
Ramlachan N et al. A comparative study on the effects of tylosin on select bacteria during continuous flow culture of mixed populations of gut microflora derived from a feral and a domestic pig. 2008 Foodborne Pathog. Dis. pmid:18260812
Jacob ME et al. Effects of feeding wet corn distillers grains with solubles with or without monensin and tylosin on the prevalence and antimicrobial susceptibilities of fecal foodborne pathogenic and commensal bacteria in feedlot cattle. 2008 J. Anim. Sci. pmid:18192558
Clark C et al. Pharmacokinetics of tilmicosin in equine tissues and plasma. 2008 J. Vet. Pharmacol. Ther. pmid:18177321
Smith LK and Mankin AS Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. 2008 Antimicrob. Agents Chemother. pmid:18299405
Aust MO et al. Distribution of sulfamethazine, chlortetracycline and tylosin in manure and soil of Canadian feedlots after subtherapeutic use in cattle. 2008 Environ. Pollut. pmid:18440678
Douthwaite S et al. Interaction of the tylosin-resistance methyltransferase RlmA II at its rRNA target differs from the orthologue RlmA I. 2008 J. Mol. Biol. pmid:18406425
Reuter RR et al. Effects of dietary energy source and level and injection of tilmicosin phosphate on immune function in lipopolysaccharide-challenged beef steers. 2008 J. Anim. Sci. pmid:18407986
Hu D et al. Identification of tylosin photoreaction products and comparison of ELISA and HPLC methods for their detection in water. 2008 Environ. Sci. Technol. pmid:18497154
Reynaldi FJ et al. Effectiveness of tilmicosin against Paenibacillus larvae, the causal agent of American Foulbrood disease of honeybees. 2008 Vet. Microbiol. pmid:18539412
Mir PS et al. Effects of dietary sunflower seeds and tylosin phosphate on production variables, carcass characteristics, fatty acid composition, and liver abscess incidence in crossbred steers. 2008 J. Anim. Sci. pmid:18567724
Nickell JS et al. Comparison of short-term health and performance effects related to prophylactic administration of tulathromycin versus tilmicosin in long-hauled, highly stressed beef stocker calves. 2008 Vet. Ther. pmid:18597253
Chen J et al. Technical note: Occurrence in fecal microbiota of genes conferring resistance to both macrolide-lincosamide-streptogramin B and tetracyclines concomitant with feeding of beef cattle with tylosin. 2008 J. Anim. Sci. pmid:18469042
Depenbusch BE et al. Efficacy of monensin and tylosin in finishing diets based on steam-flaked corn with and without corn wet distillers grains with solubles. 2008 J. Anim. Sci. pmid:18469059
Shimada T et al. Modelling the effect of the antimicrobial tylosin on the performance of an anaerobic sequencing batch reactor. 2008 Water Sci. Technol. pmid:18547919
Gallina G et al. Acute toxicity evaluation of four antibacterials with Daphnia magna. 2008 Vet. Res. Commun. pmid:18688742
Stoev G and Nazarov V Identification of the related substances of tilmicosin by liquid chromatography/ion trap mass spectrometry. 2008 Rapid Commun. Mass Spectrom. pmid:18491285
Achard A et al. Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. 2008 Antimicrob. Agents Chemother. pmid:18519724
Shimada T et al. Inhibitory effects of the macrolide antimicrobial tylosin on anaerobic treatment. 2008 Biotechnol. Bioeng. pmid:18646223
Caldwell DB et al. Development, stability, and molecular mechanisms of macrolide resistance in Campylobacter jejuni. 2008 Antimicrob. Agents Chemother. pmid:18779354
Giadinis ND et al. Mortality in adult goats attributed to Mycoplasma capricolum subspecies capricolum. 2008 Vet. Rec. pmid:18757908
Parker KI et al. Quarter-level analysis of subclinical and clinical mastitis in primiparous heifers following the use of a teat sealant or an injectable antibiotic, or both, precalving. 2008 J. Dairy Sci. pmid:18096938
Crespo R and McMillan R Facial cellulitis induced in chickens by Mycoplasma gallisepticum bacterin and its treatment. 2008 Avian Dis. pmid:19166067
Van Donkersgoed J et al. Comparative efficacy of tilmicosin versus tulathromycin as a metaphylactic antimicrobial in feedlot calves at moderate risk for respiratory disease. 2008 Vet. Ther. pmid:19177334
Lilia G et al. Circadian serum concentrations of tylosin in broilers after feed or water medication. 2008 Br. Poult. Sci. pmid:18836909
Cundliffe E Control of tylosin biosynthesis in Streptomyces fradiae. 2008 J. Microbiol. Biotechnol. pmid:18852501
Nathues H and grosse Beilage E Diagnosis of Lawsonia intracellularis infection in pigs after vaccination or antimicrobial treatment. 2008 DTW. Dtsch. Tierarztl. Wochenschr. pmid:19024547
Oakes J and Seifert S American association of poison control centers database characterization of human tilmicosin exposures, 2001-2005. 2008 J Med Toxicol pmid:19031373
Catry B et al. Efficacy of metaphylactic florfenicol therapy during natural outbreaks of bovine respiratory disease. 2008 J. Vet. Pharmacol. Ther. pmid:19000268
Fricke JA et al. Pharmacokinetics and tissue depletion of tilmicosin in turkeys. 2008 J. Vet. Pharmacol. Ther. pmid:19000285
Beltran-Alcrudo D et al. A persistent outbreak of ulcerative enteritis in bobwhite quail (Colinus virginianus). 2008 Avian Dis. pmid:18939648
Weber TE and Kerr BJ Effect of sodium butyrate on growth performance and response to lipopolysaccharide in weanling pigs. 2008 J. Anim. Sci. pmid:17998428
Pol-Hofstad I et al. Collaborative study of a microbiological screening method (three-plate) for the banned antimicrobial growth promotors tylosin, virginiamycin, spiramycin, zinc bacitracin and avoparcin in animal feed. 2008 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:19680856
Blackwood RS et al. Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta). 2008 Comp. Med. pmid:19793461
Demoling LA and Bååth E No long-term persistence of bacterial pollution-induced community tolerance in tylosin-polluted soil. 2008 Environ. Sci. Technol. pmid:18853809
Castonguay R et al. Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase. 2008 J. Am. Chem. Soc. pmid:18693734
Petropoulos AD et al. Stepwise binding of tylosin and erythromycin to Escherichia coli ribosomes, characterized by kinetic and footprinting analysis. 2008 J. Biol. Chem. pmid:18079110
Akhter S et al. Effect of antibiotics in extender on bacterial and spermatozoal quality of cooled buffalo (Bubalus bubalis) bull semen. 2008 Reprod. Domest. Anim. pmid:18042206
Bailey M et al. Induction of erm(C) expression by noninducing antibiotics. 2008 Antimicrob. Agents Chemother. pmid:18086834
Diagnosis | pasteurellosis. 2008 Lab Anim (NY) pmid:18094697
Wagner BA et al. Effect of antimicrobial dosage regimen on Salmonella and Escherichia coli isolates from feeder swine. 2008 Appl. Environ. Microbiol. pmid:18223115
Kim MH et al. Comparative pharmacokinetics of tylosin or florfenicol after a single intramuscular administration at two different doses of tylosin-florfenicol combination in pigs. 2008 J. Vet. Med. Sci. pmid:18250580
Angenent LT et al. Effect of the presence of the antimicrobial tylosin in swine waste on anaerobic treatment. 2008 Water Res. pmid:18258277
Montgomery JL et al. Effects of dietary zilpaterol hydrochloride on feedlot performance and carcass characteristics of beef steers fed with and without monensin and tylosin. 2009 J. Anim. Sci. pmid:18997069
Bodoor K et al. Design and implementation of an ribonucleic acid (RNA) directed fragment library. 2009 J. Med. Chem. pmid:19445516