Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Mycotoxicosis D015651 5 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Tracheal Diseases D014133 3 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Scott DW et al. Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. 1996 Can. Vet. J. pmid:8896878
Houglum JE and Tasler MK Liquid chromatographic assay of tylosin in animal feeds. 1996 Mar-Apr J AOAC Int pmid:8920123
Delépine B et al. Multiresidue method for confirmation of macrolide antibiotics in bovine muscle by liquid chromatography/mass spectrometry. 1996 Mar-Apr J AOAC Int pmid:8920126
Zuzulova M et al. In vitro activity of tylosin and its derivatives against Ureaplasma urealyticum. 1995 Arzneimittelforschung pmid:8929244
Markakis PK Microbiological method for determining macrolides in animal feeds in the presence of other drugs by thin-layer chromatography detection. 1996 Nov-Dec J AOAC Int pmid:8946704
Kobayashi H et al. In vitro susceptibility of Mycoplasma hyosynoviae and M. hyorhinis to antimicrobial agents. 1996 J. Vet. Med. Sci. pmid:8959659
Fish SA and Cundliffe E Structure-activity studies of tylosin-related macrolides. 1996 J. Antibiot. pmid:8968399
Gandecha AR and Cundliffe E Molecular analysis of tlrD, an MLS resistance determinant from the tylosin producer, Streptomyces fradiae. 1996 Gene pmid:8973363
Kuhstoss S et al. Production of a novel polyketide through the construction of a hybrid polyketide synthase. 1996 Gene pmid:8996112
McOrist S et al. Oral administration of tylosin phosphate for treatment and prevention of proliferative enteropathy in pigs. 1997 Am. J. Vet. Res. pmid:9028475
Gandecha AR et al. Analysis of four tylosin biosynthetic genes from the tylLM region of the Streptomyces fradiae genome. 1997 Gene pmid:9031628
Baltz RH et al. Applications of transposition mutagenesis in antibiotic producing streptomycetes. 1997 Antonie Van Leeuwenhoek pmid:9049029
McFarland JW et al. Repromicin derivatives with potent antibacterial activity against Pasteurella multocida. 1997 J. Med. Chem. pmid:9083494
McFarland JW et al. Quantitative structure-activity relationships among macrolide antibacterial agents: in vitro and in vivo potency against Pasteurella multocida. 1997 J. Med. Chem. pmid:9135031
Memili E and Weisblum B Essential role of endogenously synthesized tylosin for induction of ermSF in Streptomyces fradiae. 1997 Antimicrob. Agents Chemother. pmid:9145902
Ramadan A Pharmacokinetics of tilmicosin in serum and milk of goats. 1997 Jan-Feb Res. Vet. Sci. pmid:9160424
Mironov VA et al. [Effect of Ca2+ ions on biosynthesis and component composition of tylosin in Streptomyces fradiae]. 1997 Antibiot. Khimioter. pmid:9182505
Morck DW et al. Treatment of experimentally induced pneumonic pasteurellosis of young calves with tilmicosin. 1997 Can. J. Vet. Res. pmid:9242998
Residues of some veterinary drugs in animals and foods. Monographs prepared by the Forty-Seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives. Rome, 4-13 June 1996. 1997 FAO Food Nutr Pap pmid:9253593
Naranda A et al. New dihydro and tetrahydro derivatives of desmycosin. III. The opening of oxirane ring of 12,13-epoxydesmycosin. 1997 J. Antibiot. pmid:9402992