Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Mycotoxicosis D015651 5 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Tracheal Diseases D014133 3 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Gotoh Y et al. Chemical transformation of tylosin derivatives into neutral macrolides having a 3'-methoxyl group. 1998 Carbohydr. Res. pmid:9720235
Synek M et al. [Immunologic aspects of macrolide antibiotics]. 1989 Cas. Lek. Cesk. pmid:2731206
Bébrová E et al. [Immunologic reactivity of tylosin and erythromycin]. 1989 Cesk Epidemiol Mikrobiol Imunol pmid:2790978
Butler AR et al. Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiae. 1999 Chem. Biol. pmid:10322123
Starosta AL et al. Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition. 2010 Chem. Biol. pmid:20534348
Bate N et al. Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae. 1999 Chem. Biol. pmid:10467127
Stratigopoulos G and Cundliffe E Expression analysis of the tylosin-biosynthetic gene cluster: pivotal regulatory role of the tylQ product. 2002 Chem. Biol. pmid:11841940
De Liguoro M et al. Use of oxytetracycline and tylosin in intensive calf farming: evaluation of transfer to manure and soil. 2003 Chemosphere pmid:12729703
Chen C et al. Effect of composting and soil type on dissipation of veterinary antibiotics in land-applied manures. 2018 Chemosphere pmid:29306199
Kolz AC et al. Sorption of tylosin onto swine manure. 2005 Chemosphere pmid:15914248
Rabølle M and Spliid NH Sorption and mobility of metronidazole, olaquindox, oxytetracycline and tylosin in soil. 2000 Chemosphere pmid:10705549
Baguer AJ et al. Effects of the antibiotics oxytetracycline and tylosin on soil fauna. 2000 Chemosphere pmid:10705553
Loke ML et al. Stability of Tylosin A in manure containing test systems determined by high performance liquid chromatography. 2000 Chemosphere pmid:10705554
Hossain A et al. Occurrence, distribution, ecological and resistance risks of antibiotics in surface water of finfish and shellfish aquaculture in Bangladesh. 2017 Chemosphere pmid:28888121
Blackwell PA et al. The dissipation and transport of veterinary antibiotics in a sandy loam soil. 2007 Chemosphere pmid:17204303
Guo X et al. Sorption properties of tylosin on four different microplastics. 2018 Chemosphere pmid:29933160
Stromer BS et al. Tylosin sorption to diatomaceous earth described by Langmuir isotherm and Freundlich isotherm models. 2018 Chemosphere pmid:29874766
Mitchell SM et al. Hydrolysis of amphenicol and macrolide antibiotics: Chloramphenicol, florfenicol, spiramycin, and tylosin. 2015 Chemosphere pmid:25618189
Yin Y et al. Iron and manganese oxides modified maize straw to remove tylosin from aqueous solutions. 2018 Chemosphere pmid:29689529
Ali M et al. Effect of redox potential and pH status on degradation and adsorption behavior of tylosin in dairy lagoon sediment suspension. 2013 Chemosphere pmid:23352520
Zhang Q et al. Sorption of tylosin on clay minerals. 2013 Chemosphere pmid:24007614
Halling-Sørensen B Algal toxicity of antibacterial agents used in intensive farming. 2000 Chemosphere pmid:10705551
Blackwell PA et al. Effects of agricultural conditions on the leaching behaviour of veterinary antibiotics in soils. 2009 Chemosphere pmid:19128817
van der Grinten E et al. Comparing the sensitivity of algal, cyanobacterial and bacterial bioassays to different groups of antibiotics. 2010 Chemosphere pmid:20430416
Loke ML et al. Determination of the distribution coefficient (log Kd) of oxytetracycline, tylosin A, olaquindox and metronidazole in manure. 2002 Chemosphere pmid:12146624
Grdisa M et al. Effect of a 17-member azalide on tumor cell growth. 1998 Sep-Oct Chemotherapy pmid:9732149
Besserer F et al. Tilmicosin toxicity: a case of accidental human tilmicosin injection managed with calcium, high-dose insulin and intravenous lipid emulsion therapy. 2016 Clin Toxicol (Phila) pmid:27207720
Blackwood RS et al. Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta). 2008 Comp. Med. pmid:19793461
Tuomi ML and Räsänen L Contact allergy to tylosin and cobalt in a pig-farmer. 1995 Contact Derm. pmid:8654098
Caraffini S et al. Tylosin, an airborne contact allergen in veterinarians. 1994 Contact Derm. pmid:7867337
Danese P et al. Occupational contact dermatitis from tylosin. 1994 Contact Derm. pmid:8187499
Whitehead TR and Cotta MA Sequence analyses of a broad host-range plasmid containing ermT from a tylosin-resistant Lactobacillus sp. Isolated from swine feces. 2001 Curr. Microbiol. pmid:11375658
Zhang AJ and Warshaw EM Pet Consort Dermatitis: The Importance of Asking About Pets. Dermatitis pmid:29901502
Malaiyandi V et al. Airborne allergic contact dermatitis from tylosin in pharmacy compounders and cross-sensitization to macrolide antibiotics. 2012 Sep-Oct Dermatitis pmid:23010831
Jung HD [Occupationally-induced contact eczema by tylosin (Tylan)]. 1983 Dermatol Monatsschr pmid:6222923
Song M et al. The controlled release of tilmicosin from silica nanoparticles. 2011 Drug Dev Ind Pharm pmid:21204738
Atef M et al. Effect of albendazole administration on pharmacokinetic aspects of tylosin in lactating goats. 2009 Drug Metab Lett pmid:19702546
Nathues H and grosse Beilage E Diagnosis of Lawsonia intracellularis infection in pigs after vaccination or antimicrobial treatment. 2008 DTW. Dtsch. Tierarztl. Wochenschr. pmid:19024547
Atef M et al. Disposition of tylosin in goats. 1991 DTW. Dtsch. Tierarztl. Wochenschr. pmid:1790764
Dzapo V and Reiner G [The nutritive effect of avilamycin in swine breeding and fattening]. 1991 DTW. Dtsch. Tierarztl. Wochenschr. pmid:1954859
Atef M et al. Elimination of tilmicosin in lactating ewes. 1999 DTW. Dtsch. Tierarztl. Wochenschr. pmid:10481373
el-Sayed MG et al. Pharmacokinetic profile of tylosin in mastitic cows. 1986 DTW. Dtsch. Tierarztl. Wochenschr. pmid:3530702
Kietzmann M [Comparative study of the distribution and excretion of tylosin of various origins]. 1985 DTW. Dtsch. Tierarztl. Wochenschr. pmid:3899580
Guo X et al. Maize straw decorated with sulfide for tylosin removal from the water. 2018 Ecotoxicol. Environ. Saf. pmid:29355772
Ingerslev F and Halling-Sørensen B Biodegradability of metronidazole, olaquindox, and tylosin and formation of tylosin degradation products in aerobic soil--manure slurries. 2001 Ecotoxicol. Environ. Saf. pmid:11222042
Lebars I et al. Structure of 23S rRNA hairpin 35 and its interaction with the tylosin-resistance methyltransferase RlmAII. 2003 EMBO J. pmid:12514124
Dong H et al. Synthesis and characterization of Ag/BiWO/GO composite for the fast degradation of tylosin under visible light. 2018 Environ Sci Pollut Res Int pmid:29442310
Ferrag-Siagh F et al. Electro-Fenton pretreatment for the improvement of tylosin biodegradability. 2014 Environ Sci Pollut Res Int pmid:24705893
Guo X et al. The influences of pH and ionic strength on the sorption of tylosin on goethite. 2014 Environ Sci Pollut Res Int pmid:24197966
Yahiaoui I et al. Removal of a mixture tetracycline-tylosin from water based on anodic oxidation on a glassy carbon electrode coupled to activated sludge. Environ Technol pmid:25650749