Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Primate Diseases D018419 2 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Digital Dermatitis D058066 3 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Gallina G et al. Acute toxicity evaluation of four antibacterials with Daphnia magna. 2008 Vet. Res. Commun. pmid:18688742
Stoev G and Nazarov V Identification of the related substances of tilmicosin by liquid chromatography/ion trap mass spectrometry. 2008 Rapid Commun. Mass Spectrom. pmid:18491285
Achard A et al. Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. 2008 Antimicrob. Agents Chemother. pmid:18519724
Shimada T et al. Inhibitory effects of the macrolide antimicrobial tylosin on anaerobic treatment. 2008 Biotechnol. Bioeng. pmid:18646223
Caldwell DB et al. Development, stability, and molecular mechanisms of macrolide resistance in Campylobacter jejuni. 2008 Antimicrob. Agents Chemother. pmid:18779354
Giadinis ND et al. Mortality in adult goats attributed to Mycoplasma capricolum subspecies capricolum. 2008 Vet. Rec. pmid:18757908
Parker KI et al. Quarter-level analysis of subclinical and clinical mastitis in primiparous heifers following the use of a teat sealant or an injectable antibiotic, or both, precalving. 2008 J. Dairy Sci. pmid:18096938
Crespo R and McMillan R Facial cellulitis induced in chickens by Mycoplasma gallisepticum bacterin and its treatment. 2008 Avian Dis. pmid:19166067
Van Donkersgoed J et al. Comparative efficacy of tilmicosin versus tulathromycin as a metaphylactic antimicrobial in feedlot calves at moderate risk for respiratory disease. 2008 Vet. Ther. pmid:19177334
Lilia G et al. Circadian serum concentrations of tylosin in broilers after feed or water medication. 2008 Br. Poult. Sci. pmid:18836909
Cundliffe E Control of tylosin biosynthesis in Streptomyces fradiae. 2008 J. Microbiol. Biotechnol. pmid:18852501
Catry B et al. Efficacy of metaphylactic florfenicol therapy during natural outbreaks of bovine respiratory disease. 2008 J. Vet. Pharmacol. Ther. pmid:19000268
Fricke JA et al. Pharmacokinetics and tissue depletion of tilmicosin in turkeys. 2008 J. Vet. Pharmacol. Ther. pmid:19000285
Beltran-Alcrudo D et al. A persistent outbreak of ulcerative enteritis in bobwhite quail (Colinus virginianus). 2008 Avian Dis. pmid:18939648
Pol-Hofstad I et al. Collaborative study of a microbiological screening method (three-plate) for the banned antimicrobial growth promotors tylosin, virginiamycin, spiramycin, zinc bacitracin and avoparcin in animal feed. 2008 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:19680856
Blackwood RS et al. Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta). 2008 Comp. Med. pmid:19793461
Demoling LA and Bååth E No long-term persistence of bacterial pollution-induced community tolerance in tylosin-polluted soil. 2008 Environ. Sci. Technol. pmid:18853809
Castonguay R et al. Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase. 2008 J. Am. Chem. Soc. pmid:18693734
Petropoulos AD et al. Stepwise binding of tylosin and erythromycin to Escherichia coli ribosomes, characterized by kinetic and footprinting analysis. 2008 J. Biol. Chem. pmid:18079110
Akhter S et al. Effect of antibiotics in extender on bacterial and spermatozoal quality of cooled buffalo (Bubalus bubalis) bull semen. 2008 Reprod. Domest. Anim. pmid:18042206
Bailey M et al. Induction of erm(C) expression by noninducing antibiotics. 2008 Antimicrob. Agents Chemother. pmid:18086834
Diagnosis | pasteurellosis. 2008 Lab Anim (NY) pmid:18094697
Wagner BA et al. Effect of antimicrobial dosage regimen on Salmonella and Escherichia coli isolates from feeder swine. 2008 Appl. Environ. Microbiol. pmid:18223115
Kim MH et al. Comparative pharmacokinetics of tylosin or florfenicol after a single intramuscular administration at two different doses of tylosin-florfenicol combination in pigs. 2008 J. Vet. Med. Sci. pmid:18250580
Angenent LT et al. Effect of the presence of the antimicrobial tylosin in swine waste on anaerobic treatment. 2008 Water Res. pmid:18258277
Korshunova GA et al. [Peptide derivatives of tylosin-related macrolides]. 2007 Mar-Apr Bioorg. Khim. pmid:17476984
Sassman SA et al. Sorption of tylosin A, D, and A-aldol and degradation of tylosin A in soils. 2007 Environ. Toxicol. Chem. pmid:17702335
Ladely SR et al. Development of macrolide-resistant Campylobacter in broilers administered subtherapeutic or therapeutic concentrations of tylosin. 2007 J. Food Prot. pmid:17803155
Martínez MF and Barth AD Early detection and treatment of vesicular adenitis in bulls. 2007 Anim. Reprod. Sci. pmid:17027202
Lüthje P and Schwarz S Molecular analysis of constitutively expressed erm(C) genes selected in vitro in the presence of the non-inducers pirlimycin, spiramycin and tylosin. 2007 J. Antimicrob. Chemother. pmid:17085767
Szczepanowski R et al. Novel macrolide resistance module carried by the IncP-1beta resistance plasmid pRSB111, isolated from a wastewater treatment plant. 2007 Antimicrob. Agents Chemother. pmid:17101677
Blackwell PA et al. The dissipation and transport of veterinary antibiotics in a sandy loam soil. 2007 Chemosphere pmid:17204303
Elkins CA and Mullis LB Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. 2007 Antimicrob. Agents Chemother. pmid:17210767
Booker CW et al. Evaluation of the efficacy of tulathromycin as a metaphylactic antimicrobial in feedlot calves. 2007 Vet. Ther. pmid:17926304
Boissevain I [Punishment after the fact]. 2007 Tijdschr Diergeneeskd pmid:17939495
González de la Huebra MJ et al. Sample preparation strategy for the simultaneous determination of macrolide antibiotics in animal feedingstuffs by liquid chromatography with electrochemical detection (HPLC-ECD). 2007 J Pharm Biomed Anal pmid:17257795
Kart A et al. The possible protective effect of L-carnitine on tilmicosin-induced cardiotoxicity in mice. 2007 J Vet Med A Physiol Pathol Clin Med pmid:17381679
Lin J et al. Effect of macrolide usage on emergence of erythromycin-resistant Campylobacter isolates in chickens. 2007 Antimicrob. Agents Chemother. pmid:17353243
Litterio NJ et al. Microbiological screening test validation for detection of tylosin excretion in milk of cows with low and high somatic cell counts. 2007 J Vet Med A Physiol Pathol Clin Med pmid:17359452
Thompson TS et al. Degradation of incurred tylosin to desmycosin--implications for residue analysis of honey. 2007 Anal. Chim. Acta pmid:17386728
Hu D and Coats JR Aerobic degradation and photolysis of tylosin in water and soil. 2007 Environ. Toxicol. Chem. pmid:17521133
Song W et al. Determination of amprolium, carbadox, monensin, and tylosin in surface water by liquid chromatography/tandem mass spectrometry. 2007 Rapid Commun. Mass Spectrom. pmid:17510929
Vincent U et al. Validation of an analytical method for the determination of spiramycin, virginiamycin and tylosin in feeding-stuffs by thin-layer chromatography and bio-autography. 2007 Food Addit Contam pmid:17454108
Berrang ME et al. Subtherapeutic tylosin phosphate in broiler feed affects Campylobacter on carcasses during processing. 2007 Poult. Sci. pmid:17495097
Herrera M et al. Quantitative determination of tilmicosin in canine serum by high performance liquid chromatography-tandem mass spectrometry. 2007 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:17627909
Xie W et al. [Determination of five macrolide antibiotic residues in royal jelly samples by using high performance liquid chromatography tandem mass spectrometry]. 2007 Se Pu pmid:17679440
Werner JJ et al. Environmental photochemistry of tylosin: efficient, reversible photoisomerization to a less-active isomer, followed by photolysis. 2007 J. Agric. Food Chem. pmid:17655244
Antunes NT et al. In vitro susceptibilities of Mycoplasma putrefaciens field isolates. 2007 Antimicrob. Agents Chemother. pmid:17638695
Nagaraja TG and Lechtenberg KF Liver abscesses in feedlot cattle. 2007 Vet. Clin. North Am. Food Anim. Pract. pmid:17606156
Murphy MW et al. Airborne antibiotic concentrations in a swine feeding operation. 2007 J Agric Saf Health pmid:18075012