Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Cattle Diseases D002418 24 associated lipids
Campylobacter Infections D002169 13 associated lipids
Body Weight D001835 333 associated lipids
Bacteriuria D001437 7 associated lipids
Bacterial Infections D001424 21 associated lipids
Ataxia D001259 20 associated lipids
Asthma D001249 52 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Buret AG Immuno-modulation and anti-inflammatory benefits of antibiotics: the example of tilmicosin. 2010 Can. J. Vet. Res. pmid:20357951
Van Donkersgoed J et al. Drug residues recovered in feed after various feedlot mixer truck cleanout procedures. 2010 J. Food Prot. pmid:20051207
Lindemann MD et al. Evaluation of antibiotic effects on phosphorus digestibility and utilization by growing-finishing pigs fed a phosphorus-deficient, corn-soybean meal diet. 2010 J. Anim. Sci. pmid:20081078
Elkins CA et al. Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. 2010 Antimicrob. Agents Chemother. pmid:20038628
Giordano R et al. Effect of a high dose of three antibiotics on the reproduction of a parthenogenetic strain of Folsomia candida (Isotomidae: Collembola). 2010 Environ. Entomol. pmid:22127168
Barbour EK et al. Impact of synergism of calcium phosphomycin/tylosin tartarate supplements on the performance of broilers in the Lebanon. 2010 Jan-Mar Vet. Ital. pmid:20391366
Sumbatian NV et al. [Amino acid and peptide derivatives of the tylosin family of macrolide antibiotics modified at the aldehyde group]. 2010 Mar-Apr Bioorg. Khim. pmid:20531486
Reynaldi FJ et al. [Binding of tylosin, tilmicosin and oxytetracycline to proteins from honeybees, larvae and beehive products]. 2010 Oct-Dec Rev. Argent. Microbiol. pmid:21229198
Shimada T et al. Effects of the antimicrobial tylosin on the microbial community structure of an anaerobic sequencing batch reactor. 2011 Biotechnol. Bioeng. pmid:20830676
Kim EY et al. Pharmacokinetics of a florfenicol-tylosin combination after intravenous and intramuscular administration to beagle dogs. 2011 J. Vet. Med. Sci. pmid:21068517
Bosi P et al. Feed supplemented with 3 different antibiotics improved food intake and decreased the activation of the humoral immune response in healthy weaned pigs but had differing effects on intestinal microbiota. 2011 J. Anim. Sci. pmid:21724943
Park JW et al. Generation of reduced macrolide analogs by regio-specific biotransformation. 2011 J. Antibiot. pmid:21102594
Ci X et al. Anti-inflammatory effects of tilmicosin in a noninfectious mouse model of allergic asthma. 2011 Immunopharmacol Immunotoxicol pmid:21428709
Zheng Y et al. Molecularly imprinted solid-phase extraction for determination of tilmicosin in feed using high performance liquid chromatography. 2011 Anal. Chim. Acta pmid:21435486
Kalmokoff M et al. Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. 2011 J. Appl. Microbiol. pmid:21395944
Juntunen P et al. Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. 2011 Vet. Microbiol. pmid:21397412
Cooprider KL et al. Feedlot efficiency implications on greenhouse gas emissions and sustainability. 2011 J. Anim. Sci. pmid:21398565
Bernal J et al. Determination of tylosins A, B, C and D in bee larvae by liquid chromatography coupled to ion trap-tandem mass spectrometry. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21498134
Smee NM and Towell TL What is the evidence? Inflammatory bowel disease in a dog. 2011 J. Am. Vet. Med. Assoc. pmid:21529230
Kilpinen S et al. Effect of tylosin on dogs with suspected tylosin-responsive diarrhea: a placebo-controlled, randomized, double-blinded, prospective clinical trial. 2011 Acta Vet. Scand. pmid:21489311
Alexander TW et al. Longitudinal characterization of antimicrobial resistance genes in feces shed from cattle fed different subtherapeutic antibiotics. 2011 BMC Microbiol. pmid:21261985
Ozaki H et al. Antimicrobial resistance in fecal Escherichia coli isolated from growing chickens on commercial broiler farms. 2011 Vet. Microbiol. pmid:21232883
Song M et al. The controlled release of tilmicosin from silica nanoparticles. 2011 Drug Dev Ind Pharm pmid:21204738
Stead SL et al. Development and validation of a potentiometric biosensor assay for tylosin with demonstrated applicability for the detection of two other antimicrobial growth-promoter compounds in feedstuffs. 2011 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:21574083
Kucerova Z et al. Antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolates from clinical outbreaks of porcine respiratory diseases. 2011 Vet. Microbiol. pmid:21316872
Hidalgo Á et al. Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain. 2011 Antimicrob. Agents Chemother. pmid:21555771
Guan S et al. Immunosuppressive activity of tilmicosin on the immune responses in mice. 2011 Immunopharmacol Immunotoxicol pmid:20718577
Lombardi KR et al. Pharmacokinetics of tilmicosin in beef cattle following intravenous and subcutaneous administration. 2011 J. Vet. Pharmacol. Ther. pmid:21323676
Xie S et al. Acute toxicity study of tilmicosin-loaded hydrogenated castor oil-solid lipid nanoparticles. 2011 Part Fibre Toxicol pmid:22098626
Danzeisen JL et al. Modulations of the chicken cecal microbiome and metagenome in response to anticoccidial and growth promoter treatment. 2011 PLoS ONE pmid:22114729
Forrester CA et al. Mycoplasma gallisepticum in pheasants and the efficacy of tylvalosin to treat the disease. 2011 Avian Pathol. pmid:22107092
Bohm DA et al. Preparation and characterisation of in-house reference material of tylosin in honey and results of a proficiency test. 2011 Anal. Chim. Acta pmid:21742117
Dinh QT et al. Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. 2011 Talanta pmid:21807177
Gerchman I et al. Characterization of in vivo-acquired resistance to macrolides of Mycoplasma gallisepticum strains isolated from poultry. 2011 Vet. Res. pmid:21810258
Ashenafi D et al. An improved liquid chromatographic method for the analysis of tylosin and its impurities. 2011 J Sep Sci pmid:21812113
Chelliapan S et al. Tolerance of the antibiotic tylosin on treatment performance of an up-flow anaerobic stage reactor (UASR). 2011 Water Sci. Technol. pmid:21866757
Stone JJ et al. Land application of tylosin and chlortetracycline swine manure: Impacts to soil nutrients and soil microbial community structure. 2011 J Environ Sci Health B pmid:21877979
Han AR et al. Biosynthesis of glycosylated derivatives of tylosin in Streptomyces venezuelae. 2011 J. Microbiol. Biotechnol. pmid:21715968
McClary DG et al. Relationship of in vitro minimum inhibitory concentrations of tilmicosin against Mannheimia haemolytica and Pasteurella multocida and in vivo tilmicosin treatment outcome among calves with signs of bovine respiratory disease. 2011 J. Am. Vet. Med. Assoc. pmid:21718206
Lust EB et al. Human health hazards of veterinary medications: information for emergency departments. 2011 J Emerg Med pmid:20045604
Andersen NM et al. Inhibition of protein synthesis on the ribosome by tildipirosin compared with other veterinary macrolides. 2012 Antimicrob. Agents Chemother. pmid:22926570
Liu Y et al. Transcriptional profiling of Haemophilus parasuis SH0165 response to tilmicosin. 2012 Microb. Drug Resist. pmid:22935051
Kim HB et al. Microbial shifts in the swine distal gut in response to the treatment with antimicrobial growth promoter, tylosin. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22955886
Menge M et al. Pharmacokinetics of tildipirosin in bovine plasma, lung tissue, and bronchial fluid (from live, nonanesthetized cattle). 2012 J. Vet. Pharmacol. Ther. pmid:22188102
Granados-Chinchilla F et al. A novel green chemistry method for nonaqueous extraction and high-performance liquid chromatography detection of first-, second-, and third-generation tetracyclines, 4-epitetracycline, and tylosin in animal feeds. 2012 J. Agric. Food Chem. pmid:22738432
Hagenbuch IM and Pinckney JL Toxic effect of the combined antibiotics ciprofloxacin, lincomycin, and tylosin on two species of marine diatoms. 2012 Water Res. pmid:22819871
Devreese M et al. Interaction between tylosin and bentonite clay from a pharmacokinetic perspective. 2012 Vet. J. pmid:22749117
Abutarbush SM et al. Comparison of enrofloxacin and ceftiofur sodium for the treatment of relapse of undifferentiated fever/bovine respiratory disease in feedlot cattle. 2012 Can. Vet. J. pmid:22753964
Kim KR et al. Decline in extractable antibiotics in manure-based composts during composting. 2012 Waste Manag pmid:21865024
Wang XF et al. Enhancement of antibacterial activity of tilmicosin against Staphylococcus aureus by solid lipid nanoparticles in vitro and in vivo. 2012 Vet. J. pmid:21900026