Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Enterotoxemia D004767 1 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Digital Dermatitis D058066 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Lum AM et al. Reverse engineering of industrial pharmaceutical-producing actinomycete strains using DNA microarrays. 2004 Metab. Eng. pmid:15256208
Baltadzhieva D et al. [Analysis of immunological indices of occupational sensibilization to tylosin]. 1999 Med Tr Prom Ekol pmid:10605285
Lowell JE et al. Growth performance, carcass quality, fresh belly characteristics, and commercial bacon slicing yields of growing-finishing pigs fed a subtherapeutic dose of an antibiotic, a natural antimicrobial, or not fed an antibiotic or antimicrobial. 2018 Meat Sci. pmid:29107868
Pinckney JL et al. Sublethal effects of the antibiotic tylosin on estuarine benthic microalgal communities. 2013 Mar. Pollut. Bull. pmid:23398744
Meisel ML et al. Tylosin inhibits the steroidogenesis in mouse Leydig cells "in vitro". 1993 Life Sci. pmid:8390595
Davies R and Roberts TA Antimicrobial susceptibility of enterococci recovered from commercial swine carcasses: effect of feed additives. 1999 Lett. Appl. Microbiol. pmid:10664974
Patterson J et al. Selected culturable enteric bacterial populations are modified by diet acidification and the growth promotant Tylosin. 2005 Lett. Appl. Microbiol. pmid:16033507
Lee SH Ammonium ion affecting tylosin production by Streptomyces fradiae NRRL 2702 in continuous culture. 1997 Lett. Appl. Microbiol. pmid:9418071
Whitehead TR and Cotta MA Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. 2013 Lett. Appl. Microbiol. pmid:23297734
Khaliq S et al. Production of tylosin in solid-state fermentation by Streptomyces fradiae NRRL-2702 and its gamma-irradiated mutant (gamma-1). 2009 Lett. Appl. Microbiol. pmid:19780953
Lee SH and Rho YT Improvement of tylosin fermentation by mutation and medium optimization. 1999 Lett. Appl. Microbiol. pmid:10206653
Mathieson PW et al. Mercuric chloride-treated brown Norway rats develop widespread tissue injury including necrotizing vasculitis. 1992 Lab. Invest. pmid:1625442
Modric S et al. Effect of respiratory tract disease on pharmacokinetics of tilmicosin in rats. 1999 Lab. Anim. Sci. pmid:10403438
Diagnosis | pasteurellosis. 2008 Lab Anim (NY) pmid:18094697
Takahashi I et al. [In vitro resistance acquisition in Mycoplasma gallisepticum against ofloxacin, tylosin and spectinomycin]. 2002 Jpn J Antibiot pmid:12199113
Neiffer DL Clostridium perfringens enterotoxicosis in two Amur leopards (Panthera pardus orientalis). 2001 J. Zoo Wildl. Med. pmid:12790411
Simpson EJ et al. A simple method for the removal of mycoplasma contamination from paramyxovirus stocks. 1983 J. Virol. Methods pmid:6190834
Coronato S et al. A simple method to eliminate mycoplasma from cell cultures. 1994 J. Virol. Methods pmid:8175949
Lee SW et al. Prevalence of porcine proliferative enteropathy and its control with tylosin in Korea. 2001 J. Vet. Sci. pmid:12441690
Hwang YH et al. Simultaneous determination of various macrolides by liquid chromatography/mass spectrometry. 2002 J. Vet. Sci. pmid:12441679