| MeSH term | MeSH ID | Detail |
|---|---|---|
| Enterotoxemia | D004767 | 1 associated lipids |
| Bovine Respiratory Disease Complex | D048090 | 2 associated lipids |
| Desulfovibrionaceae Infections | D045824 | 5 associated lipids |
| Primate Diseases | D018419 | 2 associated lipids |
| Pneumonia of Calves, Enzootic | D048089 | 2 associated lipids |
| Pneumonia of Swine, Mycoplasmal | D045729 | 2 associated lipids |
| Digital Dermatitis | D058066 | 3 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- FEMS Microbiol. Lett. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hume ME and Donskey CJ | Effect of Vancomycin, Tylosin, and Chlortetracycline on Vancomycin-Resistant Enterococcus faecium Colonization of Broiler Chickens During Grow-Out. | 2017 | Foodborne Pathog. Dis. | pmid:28128649 |
| Apley MD et al. | Use estimates of in-feed antimicrobials in swine production in the United States. | 2012 | Foodborne Pathog. Dis. | pmid:22324295 |
| Kounenis G et al. | Comparative study of erythromycin, troleandomycin and tylosin on the rabbit intestine. | 1994 | Fundam Clin Pharmacol | pmid:8020874 |
| Inouye M et al. | Cloning and sequences of two macrolide-resistance-encoding genes from mycinamicin-producing Micromonospora griseorubida. | 1994 | Gene | pmid:8163173 |
| Solenberg PJ et al. | Transposition mutagenesis in Streptomyces fradiae: identification of a neutral site for the stable insertion of DNA by transposon exchange. | 1996 | Gene | pmid:8626067 |
| Gandecha AR et al. | Analysis of four tylosin biosynthetic genes from the tylLM region of the Streptomyces fradiae genome. | 1997 | Gene | pmid:9031628 |
| Gandecha AR and Cundliffe E | Molecular analysis of tlrD, an MLS resistance determinant from the tylosin producer, Streptomyces fradiae. | 1996 | Gene | pmid:8973363 |
| Rosteck PR et al. | Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. | 1991 | Gene | pmid:1864505 |
| Zalacain M and Cundliffe E | Cloning of tlrD, a fourth resistance gene, from the tylosin producer, Streptomyces fradiae. | 1991 | Gene | pmid:1995426 |
| Wilson VT and Cundliffe E | Characterization and targeted disruption of a glycosyltransferase gene in the tylosin producer, Streptomyces fradiae. | 1998 | Gene | pmid:9651492 |
| Kuhstoss S et al. | Production of a novel polyketide through the construction of a hybrid polyketide synthase. | 1996 | Gene | pmid:8996112 |
| Baltz RH et al. | Transposition of Tn5096 and related transposons in Streptomyces species. | 1992 | Gene | pmid:1319378 |
| Takhirov MT et al. | [Determination of tylosin in the water supply using a chromatographic method]. | 1993 | Gig Sanit | pmid:8244081 |
| Forrester MB | Human exposures to tilmicosin reported to poison centres, Texas, 1998-2003. | 2005 | Hum Exp Toxicol | pmid:16004193 |
| Ci X et al. | Anti-inflammatory effects of tilmicosin in a noninfectious mouse model of allergic asthma. | 2011 | Immunopharmacol Immunotoxicol | pmid:21428709 |
| Guan S et al. | Immunosuppressive activity of tilmicosin on the immune responses in mice. | 2011 | Immunopharmacol Immunotoxicol | pmid:20718577 |
| El-Mahmoudy A and Gheith I | The anti-nociceptive potential of tilmicosin against chemical-induced but not thermal-induced pain in mice. | 2016 | Int J Immunopathol Pharmacol | pmid:26519523 |
| Chen X et al. | Preparation and evaluation of tilmicosin-loaded hydrogenated castor oil nanoparticle suspensions of different particle sizes. | 2014 | Int J Nanomedicine | pmid:24920902 |
| Zhu L et al. | Evaluation of the antibacterial activity of tilmicosin-SLN against : in vitro and in vivo studies. | 2018 | Int J Nanomedicine | pmid:30147316 |
| Niwa H et al. | Rapid detection of mutations associated with resistance to erythromycin in Campylobacter jejuni/coli by PCR and line probe assay. | 2001 | Int. J. Antimicrob. Agents | pmid:11691569 |