| MeSH term | MeSH ID | Detail |
|---|---|---|
| Enterotoxemia | D004767 | 1 associated lipids |
| Bovine Respiratory Disease Complex | D048090 | 2 associated lipids |
| Desulfovibrionaceae Infections | D045824 | 5 associated lipids |
| Primate Diseases | D018419 | 2 associated lipids |
| Pneumonia of Calves, Enzootic | D048089 | 2 associated lipids |
| Pneumonia of Swine, Mycoplasmal | D045729 | 2 associated lipids |
| Digital Dermatitis | D058066 | 3 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Appl. Environ. Microbiol. (2)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shimi IR et al. | Staphcoccomycin, a new basic macrolide antibiotic. | 1979 | J. Antibiot. | pmid:541251 |
| Kádár-Pauncz J et al. | Isolation and structure elucidation of new antibiotics related to angolamycin. | 1992 | J. Antibiot. | pmid:1399843 |
| Fujiwara T et al. | 19-Deformyl-4'-deoxydesmycosin (TMC-016): synthesis and biological properties of a unique 16-membered macrolide antibiotic. | 1989 | J. Antibiot. | pmid:2500413 |
| Kiyoshima K et al. | Structure-activity relationship studies on 4''-O-acyltylosin derivatives: significance of their 23-O-mycinosyl and 4''-O-acyl moieties in antimicrobial activity against macrolide-resistant microbes. | 1989 | J. Antibiot. | pmid:2584151 |
| Creemer LC et al. | Facile synthesis of tilmicosin and tylosin related haptens for use as protein conjugates. | 2003 | J. Antibiot. | pmid:12870814 |
| Kageyama S et al. | Synthesis of 3-deoxy-3,4-didehydro derivatives of 5-O-mycaminosyltylonolide, 5-O-(4-deoxymycaminosyl) tylonolide, and desmycosin. | 1993 | J. Antibiot. | pmid:8407589 |
| Kageyama S and Tsuchiya T | Synthesis of 2-C-methyl derivatives of 3,4'-dideoxymycaminosyltylonolide, a novel type of 16-membered macrolide antibiotic. | 1994 | J. Antibiot. | pmid:7928687 |
| Terui Y et al. | Synthesis of 2-methyl 16-membered macrolide derived from tylosin. | 2006 | J. Antibiot. | pmid:16629410 |
| Sugawara A et al. | 5-O-Mycaminosyltylonolide antibacterial derivatives: design, synthesis and bioactivity. | 2017 | J. Antibiot. | pmid:28559578 |
| Tanaka A et al. | Synthesis of 4'-deoxymycaminosyl tylonolide. | 1981 | J. Antibiot. | pmid:7309633 |
| Tanaka A et al. | Syntheses of derivatives of 4'-deoxymycaminosyl tylonolide and mycaminosyl tylonolide modified AT C-23. | 1981 | J. Antibiot. | pmid:7309634 |
| Tanaka A et al. | Syntheses of 4'-deoxy-demycarosyl tylosin and its analogues. | 1981 | J. Antibiot. | pmid:7309635 |
| Inouye S et al. | Modifications of a macrolide antibiotic midecamycin. II. Reaction of midecamycin and 9-acetylmidecamycin with dimethylsulfoxide and acetic anhydride. | 1980 | J. Antibiot. | pmid:7372551 |
| Omura S et al. | Chemical modification of tylosin. Thioether derivatives of tylosin and demycarosyltylosin. | 1984 | J. Antibiot. | pmid:6501102 |
| Sakamoto S et al. | Syntheses of 23-deoxy-23-N-ethyl-23-(2-fluoro-, 2,2-difluoro-, and 2,2,2-trifluoroethyl)amino derivatives of mycaminosyl tylonolide and 4'-deoxymycaminosyl tylonolide. | 1984 | J. Antibiot. | pmid:6526731 |
| Mutoh Y et al. | Deepoxidation of 16-membered epoxyenone macrolide antibiotics. II. Chemical deepoxidation by dissolving metal reduction. | 1984 | J. Antibiot. | pmid:6706848 |
| Sakamoto M et al. | Deepoxidation of 16-membered epoxyenone macrolide antibiotics. III. In vitro and in vivo evaluation of deepoxidation products of carbomycin A, deltamycin A1, 4"-phenylacetyldeltamycin, angolamycin and rosamicin. | 1984 | J. Antibiot. | pmid:6706849 |
| Fish SA and Cundliffe E | Structure-activity studies of tylosin-related macrolides. | 1996 | J. Antibiot. | pmid:8968399 |
| Tsutsui A et al. | Antimalarial C-9 oxime derivatives from desmycosin, produced by click chemistry. | 2013 | J. Antibiot. | pmid:23232930 |
| Cacciapuoti AF et al. | Microbiological and pharmacokinetic studies of acyl demycinosyltylosin and related tylosin derivatives. | 1990 | J. Antibiot. | pmid:2145254 |
| Kageyama S et al. | Synthesis of 3,4'-dideoxymycaminosyl tylonolide, a novel type of macrolide derivative. | 1992 | J. Antibiot. | pmid:1548187 |
| Kirst HA et al. | Structure-activity studies of 20-deoxo-20-amino derivatives of tylosin-related macrolides. | 1989 | J. Antibiot. | pmid:2684947 |
| Ruggeri C et al. | Synthesis and antibacterial activity of 9-O-[(2-methoxyethoxy)methyl]-oximes of tylosin and demycarosyltylosin. | 1989 | J. Antibiot. | pmid:2793598 |
| Marshall VP et al. | Enzymic inactivation of lincosaminide and macrolide antibiotics: divalent metal cation and coenzyme specificities. | 1989 | J. Antibiot. | pmid:2722691 |
| Wilson VT and Cundliffe E | Molecular analysis of tlrB, an antibiotic-resistance gene from tylosin-producing Streptomyces fradiae, and discovery of a novel resistance mechanism. | 1999 | J. Antibiot. | pmid:10348045 |
| Ose EE | In vitro antibacterial properties of EL-870, a new semi-synthetic macrolide antibiotic. | 1987 | J. Antibiot. | pmid:3570967 |
| Wiley PF et al. | Enzymatic phosphorylation of macrolide antibiotics. | 1987 | J. Antibiot. | pmid:3570968 |
| Kiyoshima K et al. | New tylosin analogs produced by mutants of Streptomyces fradiae. | 1987 | J. Antibiot. | pmid:3680024 |
| Takeuchi T et al. | 4''-O-(4-methoxyphenyl)-acetyltylosin, a new macrolide derivative of therapeutic importance. | 1987 | J. Antibiot. | pmid:3680047 |
| Morisaki N et al. | Glycosylative inactivation of chalcomycin and tylosin by a clinically isolated Nocardia asteroides strain. | 2001 | J. Antibiot. | pmid:11302489 |
| Jacob ME et al. | Effects of feeding wet corn distillers grains with solubles with or without monensin and tylosin on the prevalence and antimicrobial susceptibilities of fecal foodborne pathogenic and commensal bacteria in feedlot cattle. | 2008 | J. Anim. Sci. | pmid:18192558 |
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| Ives SE et al. | Effects of virginiamycin and monensin plus tylosin on ruminal protein metabolism in steers fed corn-based finishing diets with or without wet corn gluten feed. | 2002 | J. Anim. Sci. | pmid:12462270 |
| Tennant TC et al. | Comparison of tulathromycin and tilmicosin on the prevalence and severity of bovine respiratory disease in feedlot cattle in association with feedlot performance, carcass characteristics, and economic factors. | 2014 | J. Anim. Sci. | pmid:25349362 |
| Rozeboom DW et al. | Effects of mannan oligosaccharide and an antimicrobial product in nursery diets on performance of pigs reared on three different farms. | 2005 | J. Anim. Sci. | pmid:16230663 |
| Beck P et al. | Additive effects of growth promoting technologies on performance of grazing steers and economics of the wheat pasture enterprise. | 2014 | J. Anim. Sci. | pmid:24492552 |
| DiLorenzo N et al. | Effects of feeding polyclonal antibody preparations on ruminal bacterial populations and ruminal pH of steers fed high-grain diets. | 2006 | J. Anim. Sci. | pmid:16864880 |
| Mir PS et al. | Effects of dietary sunflower seeds and tylosin phosphate on production variables, carcass characteristics, fatty acid composition, and liver abscess incidence in crossbred steers. | 2008 | J. Anim. Sci. | pmid:18567724 |
| Chen J et al. | Technical note: Occurrence in fecal microbiota of genes conferring resistance to both macrolide-lincosamide-streptogramin B and tetracyclines concomitant with feeding of beef cattle with tylosin. | 2008 | J. Anim. Sci. | pmid:18469042 |
| Bosi P et al. | Feed supplemented with 3 different antibiotics improved food intake and decreased the activation of the humoral immune response in healthy weaned pigs but had differing effects on intestinal microbiota. | 2011 | J. Anim. Sci. | pmid:21724943 |
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| Hilton GG et al. | Effects of feeding zilpaterol hydrochloride with and without monensin and tylosin on carcass cutability and meat palatability of beef steers. | 2009 | J. Anim. Sci. | pmid:19028853 |
| Weber TE and Kerr BJ | Effect of sodium butyrate on growth performance and response to lipopolysaccharide in weanling pigs. | 2008 | J. Anim. Sci. | pmid:17998428 |
| Morris FE et al. | Effect of rotating monensin plus tylosin and lasalocid on performance, ruminal fermentation, and site and extent of digestion in feedlot cattle. | 1990 | J. Anim. Sci. | pmid:2254185 |
| Tan ZL et al. | Serum neutralizing antibodies against Fusobacterium necrophorum leukotoxin in cattle with experimentally induced or naturally developed hepatic abscesses. | 1994 | J. Anim. Sci. | pmid:8157537 |
| Effect of space allowance and tylosin feeding on performance of growing-finishing pigs. NCR-89 Committee on Confinement Management of Swine. | 1986 | J. Anim. Sci. | pmid:3710927 | |
| Brumm MC and Peo ER | Effect of receiving diets containing alfalfa and certain feed additives on performance of feeder pigs transported long distances. | 1985 | J. Anim. Sci. | pmid:4030523 |
| Potter EL et al. | Effect of monensin and tylosin on average daily gain, feed efficiency and liver abscess incidence in feedlot cattle. | 1985 | J. Anim. Sci. | pmid:4077750 |
| Han H et al. | Carbohydrate fermentation and nitrogen metabolism of a finishing beef diet by ruminal microbes in continuous cultures as affected by ethoxyquin and(or) supplementation of monensin and tylosin. | 2002 | J. Anim. Sci. | pmid:12002320 |