Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Bacillaceae Infections D016863 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Enterotoxemia D004767 1 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Digital Dermatitis D058066 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Skogerboe TL et al. Comparative efficacy of tulathromycin versus florfenicol and tilmicosin against undifferentiated bovine respiratory disease in feedlot cattle. 2005 Vet. Ther. pmid:16094565
Caldow M et al. Development and validation of an optical SPR biosensor assay for tylosin residues in honey. 2005 J. Agric. Food Chem. pmid:16159159
Chun S et al. Effect of agricultural antibiotics on the persistence and transformation of 17beta-estradiol in a Sequatchie loam. 2005 J Environ Sci Health B pmid:16190018
Clay SA et al. Tylosin sorption to silty clay loam soils, swine manure, and sand. 2005 J Environ Sci Health B pmid:16194921
Brumbaugh GW et al. Effect of tilmicosin on chemotactic, phagocytic, and bactericidal activities of bovine and porcine alveolar macrophages. 2002 Am. J. Vet. Res. pmid:16206777
Chander Y et al. Antibacterial activity of soil-bound antibiotics. 2005 Nov-Dec J. Environ. Qual. pmid:16221813
Kumar K et al. Antibiotic uptake by plants from soil fertilized with animal manure. 2005 Nov-Dec J. Environ. Qual. pmid:16221828
Rozeboom DW et al. Effects of mannan oligosaccharide and an antimicrobial product in nursery diets on performance of pigs reared on three different farms. 2005 J. Anim. Sci. pmid:16230663
Pringle M et al. Tiamulin resistance in porcine Brachyspira pilosicoli isolates. 2006 Res. Vet. Sci. pmid:16253666
Mathieson PW et al. Mercuric chloride-treated brown Norway rats develop widespread tissue injury including necrotizing vasculitis. 1992 Lab. Invest. pmid:1625442
Jensen LB and Aarestrup FM Regulation of the erm(C) gene in Staphylococci from reservoir with different usage of macrolides. 2005 Acta Vet. Scand. pmid:16261929
Ayling RD et al. Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection. 2005 Antimicrob. Agents Chemother. pmid:16304194
Beier RC et al. Production and characterization of monoclonal antibodies against the antibiotic tilmicosin. 2005 J. Agric. Food Chem. pmid:16332115
Fu H et al. Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides. 2006 Bioorg. Med. Chem. Lett. pmid:16343900
Westermarck E et al. Effect of diet and tylosin on chronic diarrhea in beagles. 2005 Nov-Dec J. Vet. Intern. Med. pmid:16355675
Chelliapan S et al. Performance of an up-flow anaerobic stage reactor (UASR) in the treatment of pharmaceutical wastewater containing macrolide antibiotics. 2006 Water Res. pmid:16387347
Jacobsen AM and Halling-Sørensen B Multi-component analysis of tetracyclines, sulfonamides and tylosin in swine manure by liquid chromatography-tandem mass spectrometry. 2006 Anal Bioanal Chem pmid:16485090
Jung WS et al. Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae. 2006 Appl. Microbiol. Biotechnol. pmid:16493552
Carlson JC and Mabury SA Dissipation kinetics and mobility of chlortetracycline, tylosin, and monensin in an agricultural soil in Northumberland County, Ontario, Canada. 2006 Environ. Toxicol. Chem. pmid:16494218
Nozal Nalda MJ et al. Trace analysis of antibacterial tylosin A, B, C and D in honey by liquid chromatography-electrospray ionization-mass spectrometry. 2006 J Sep Sci pmid:16544883