Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Erysipelothrix Infections D004889 1 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Enterotoxemia D004767 1 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Digital Dermatitis D058066 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Kreizinger Z et al. Antibiotic susceptibility profiles of Mycoplasma synoviae strains originating from Central and Eastern Europe. 2017 BMC Vet. Res. pmid:29149886
Weber NR et al. Batch medication of intestinal infections in nursery pigs-A randomised clinical trial on the efficacy of treatment strategy, type of antibiotic and bacterial load on average daily weight gain. 2017 Prev. Vet. Med. pmid:28107883
Zhang N et al. Determination of the Mutant Selection Window and Evaluation of the Killing of Mycoplasma gallisepticum by Danofloxacin, Doxycycline, Tilmicosin, Tylvalosin and Valnemulin. 2017 PLoS ONE pmid:28052123
Weinroth MD et al. Rapid Communication: 16S ribosomal ribonucleic acid characterization of liver abscesses in feedlot cattle from three states in the United States. 2017 J. Anim. Sci. pmid:29108068
Zhang YJ et al. Temporal succession of soil antibiotic resistance genes following application of swine, cattle and poultry manures spiked with or without antibiotics. 2017 Environ. Pollut. pmid:28964602
Ruiz VE et al. A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity. 2017 Nat Commun pmid:28894149
Prats-van der Ham M et al. Molecular resistance mechanisms of Mycoplasma agalactiae to macrolides and lincomycin. 2017 Vet. Microbiol. pmid:29102109
Samii SS et al. Effects of limonene on ruminal concentrations, fermentation, and lysine degradation in cattle. 2016 J. Anim. Sci. pmid:27695807
Tereshchenkov AG et al. New Fluorescent Macrolide Derivatives for Studying Interactions of Antibiotics and Their Analogs with the Ribosomal Exit Tunnel. 2016 Biochemistry Mosc. pmid:27908240
Li Y et al. In vitro susceptibility of four antimicrobials against Riemerella anatipestifer isolates: a comparison of minimum inhibitory concentrations and mutant prevention concentrations for ceftiofur, cefquinome, florfenicol, and tilmicosin. 2016 BMC Vet. Res. pmid:27829415
Angell JW et al. Whole-flock, metaphylactic tilmicosin failed to eliminate contagious ovine digital dermatitis and footrot in sheep: a cluster randomised trial. 2016 Vet. Rec. pmid:27450091
Galmozzi CV et al. The Cyanobacterial Ribosomal-Associated Protein LrtA Is Involved in Post-Stress Survival in Synechocystis sp. PCC 6803. 2016 PLoS ONE pmid:27442126
Cernicchiaro N et al. Meta-analysis of the effects of laidlomycin propionate, fed alone or in combination with chlortetracycline, compared with monensin sodium, fed alone or in combination with tylosin, on growth performance, health, and carcass outcomes in finishing steers in North America. 2016 J. Anim. Sci. pmid:27136025
Kim J et al. Effects of the Antibiotics Growth Promoter Tylosin on Swine Gut Microbiota. 2016 J. Microbiol. Biotechnol. pmid:26869601
Brown K et al. Antimicrobial growth promoters modulate host responses in mice with a defined intestinal microbiota. 2016 Sci Rep pmid:27929072
Cleary DW et al. Long-term antibiotic exposure in soil is associated with changes in microbial community structure and prevalence of class 1 integrons. 2016 FEMS Microbiol. Ecol. pmid:27495240
Molognoni L et al. Development of a LC-MS/MS method for the simultaneous determination of sorbic acid, natamycin and tylosin in Dulce de leche. 2016 Food Chem pmid:27283692
Canning P et al. Concentrations of tylvalosin and 3-O-acetyltylosin attained in the synovial fluid of swine after administration by oral gavage at 50 and 5 mg/kg. 2016 J. Vet. Pharmacol. Ther. pmid:27086612
Mendoza J et al. Concentrations of tilmicosin in mammary gland secretions of dairy cows following subcutaneous administration of one or two doses of an experimental preparation of tilmicosin and its efficacy against intramammary infections caused by Staphylococcus aureus. 2016 Am. J. Vet. Res. pmid:27580103
Kim E et al. Characterization of the Two Methylation Steps Involved in the Biosynthesis of Mycinose in Tylosin. 2016 J. Nat. Prod. pmid:27453999
Kline A and Pinckney JL Size-selective toxicity effects of the antimicrobial tylosin on estuarine phytoplankton communities. 2016 Environ. Pollut. pmid:27376985
Besserer F et al. Tilmicosin toxicity: a case of accidental human tilmicosin injection managed with calcium, high-dose insulin and intravenous lipid emulsion therapy. 2016 Clin Toxicol (Phila) pmid:27207720
Guo X et al. Sorption of tylosin and sulfamethazine on solid humic acid. 2016 J Environ Sci (China) pmid:27155426
Crepieux T et al. Randomized, non-inferiority trial comparing a nitric oxide releasing solution with a macrolide antibiotic for control of bovine respiratory disease in beef feedlot calves at high-risk of developing respiratory tract disease. 2016 Res. Vet. Sci. pmid:27033936
Confer AW et al. Clinical disease and lung lesions in calves experimentally inoculated with Histophilus somni five days after metaphylactic administration of tildipirosin or tulathromycin. 2016 Am. J. Vet. Res. pmid:27027834
Torres F et al. Pharmacokinetics of tildipirosin in pig tonsils. 2016 J. Vet. Pharmacol. Ther. pmid:26935349
Luby EM et al. Fate and transport of tylosin-resistant bacteria and macrolide resistance genes in artificially drained agricultural fields receiving swine manure. 2016 Sci. Total Environ. pmid:26874610
Rose M et al. A microbiological assay to estimate the antimicrobial activity of parenteral tildipirosin against foodborne pathogens and commensals in the colon of beef cattle and pigs. 2016 J. Vet. Pharmacol. Ther. pmid:26538405
El-Mahmoudy A and Gheith I The anti-nociceptive potential of tilmicosin against chemical-induced but not thermal-induced pain in mice. 2016 Int J Immunopathol Pharmacol pmid:26519523
El-Ela FI et al. Investigating the potential role of vitamin E in modulating the immunosuppressive effects of tylvalosin and florfenicol in broiler chickens. 2016 Res. Vet. Sci. pmid:27663366
Krokidis M et al. The slow dissociation rate of K-1602 contributes to the enhanced inhibitory activity of this novel alkyl-aryl-bearing fluoroketolide. 2016 J Enzyme Inhib Med Chem pmid:25807301
Amarakoon ID et al. Dissipation of Antimicrobials in a Seasonally Frozen Soil after Beef Cattle Manure Application. 2016 J. Environ. Qual. pmid:27695746
Whitehead TR and Cotta MA Examination of the Aerobic Microflora of Swine Feces and Stored Swine Manure. 2016 J. Environ. Qual. pmid:27065407
Amarakoon ID et al. Dissipation of Antimicrobials in Feedlot Manure Compost after Oral Administration versus Fortification after Excretion. 2016 J. Environ. Qual. pmid:27065397
García-Sánchez L et al. Tylosin effect on methanogenesis in an anaerobic biomass from swine wastewater treatment. 2016 Water Sci. Technol. pmid:26819401
Entorf M et al. Comparative erythromycin and tylosin susceptibility testing of streptococci from bovine mastitis. 2016 Vet. Microbiol. pmid:26732695
Xia X et al. Proteomic analysis of tylosin-resistant Mycoplasma gallisepticum reveals enzymatic activities associated with resistance. 2015 Sci Rep pmid:26584633
Lu C et al. Identification of novel tylosin analogues generated by a wblA disruption mutant of Streptomyces ansochromogenes. 2015 Microb. Cell Fact. pmid:26525981
Nobel YR et al. Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment. 2015 Nat Commun pmid:26123276
Maxwell CL et al. The effects of technology use in feedlot production systems on feedlot performance and carcass characteristics. 2015 J. Anim. Sci. pmid:26020911
Pilcher CM et al. The interaction of fiber, supplied by distillers dried grains with solubles, with an antimicrobial and a nutrient partitioning agent on nitrogen balance, water utilization, and energy digestibility in finishing pigs. 2015 J. Anim. Sci. pmid:26020889
Mercadante VR et al. Effects of anti-phospholipase A(2) antibody supplementation on dry matter intake feed efficiency, acute phase response, and blood differentials of steers fed forage- and grain-based diets. 2015 J. Anim. Sci. pmid:26020758
Lysnyansky I et al. Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. 2015 Microb. Drug Resist. pmid:25734368
Luo H et al. Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. 2015 Avian Pathol. pmid:25690020
Sura S et al. Transport of three veterinary antimicrobials from feedlot pens via simulated rainfall runoff. 2015 Sci. Total Environ. pmid:25839178
Kilpinen S et al. Oral tylosin administration is associated with an increase of faecal enterococci and lactic acid bacteria in dogs with tylosin-responsive diarrhoea. 2015 Vet. J. pmid:26049259
Whitehead TR et al. Savagea faecisuis gen. nov., sp. nov., a tylosin- and tetracycline-resistant bacterium isolated from a swine-manure storage pit. 2015 Antonie Van Leeuwenhoek pmid:25980832
Li Q et al. Co-addition of manure increases the dissipation rates of tylosin A and the numbers of resistance genes in laboratory incubation experiments. 2015 Sci. Total Environ. pmid:25958362
Le T et al. A quantum dot-based immunoassay for screening of tylosin and tilmicosin in edible animal tissues. 2015 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:25822697
Amachawadi RG et al. Effects of in-feed copper and tylosin supplementations on copper and antimicrobial resistance in faecal enterococci of feedlot cattle. 2015 J. Appl. Microbiol. pmid:25739516