Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Erysipelothrix Infections D004889 1 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Enterotoxemia D004767 1 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Primate Diseases D018419 2 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Baltz RH et al. Biosynthesis of the macrolide antibiotic tylosin. A preferred pathway from tylactone to tylosin. 1983 J. Antibiot. pmid:6833128
Omura S et al. Chimeramycins: new macrolide antibiotics produced by hybrid biosynthesis. 1983 J. Antibiot. pmid:6860432
Thurman GD et al. Diagnosis and successful treatment of subacute erysipelas in a captive dolphin. 1983 J S Afr Vet Assoc pmid:6655661
Donev B et al. [Toxicological studies of a combination of technical tylosin phosphate with bentonite (farmazin TB)]. 1983 Vet Med Nauki pmid:6659350
Omura S et al. Ribosome-binding activities and antimicrobial activities of tylosin and its related compounds. 1983 J. Antibiot. pmid:6662812
Wayner EA and Brooks CG Induction of NKCF-like activity in mixed lymphocyte-tumor cell culture: direct involvement of mycoplasma infection of tumor cells. 1984 J. Immunol. pmid:6230401
Truscott RB and Ruhnke HL The effect of antibiotics against bovine mycoplasmas and ureaplasmas. 1984 Can. J. Comp. Med. pmid:6232992
Stipkovits L et al. Efficacy of lasalocid sodium against mycoplasmas (preliminary communication). 1984 Acta Vet. Hung. pmid:6242271
Omura S et al. Ammonium ions suppress the amino acid metabolism involved in the biosynthesis of protylonolide in a mutant of Streptomyces fradiae. 1984 J. Antibiot. pmid:6511663
Stipkovits L et al. A comparison of the effect of tiamulin hydrogen fumarate and tylosin tartrate on mycoplasmas of ruminants and some animal ureaplasmas. 1984 Vet. Microbiol. pmid:6730305
Dotzlaf JE et al. Incorporation of amino acid-derived carbon into tylactone by Streptomyces fradiae GS14. 1984 Antimicrob. Agents Chemother. pmid:6424562
Mackinnon JD et al. Effect of tylosin on milk yield and dry matter intake of lactating dairy cows. 1984 Vet. Rec. pmid:6495581
Omura S et al. Chemical modification of tylosin. Thioether derivatives of tylosin and demycarosyltylosin. 1984 J. Antibiot. pmid:6501102
Dilov P et al. [Comparative studies on the resorption, anti-anemic action and growth effect of FV-82 and dextrofer-100 on pigs]. 1984 Vet Med Nauki pmid:6474828
Sakamoto S et al. Syntheses of 23-deoxy-23-N-ethyl-23-(2-fluoro-, 2,2-difluoro-, and 2,2,2-trifluoroethyl)amino derivatives of mycaminosyl tylonolide and 4'-deoxymycaminosyl tylonolide. 1984 J. Antibiot. pmid:6526731
Mutoh Y et al. Deepoxidation of 16-membered epoxyenone macrolide antibiotics. II. Chemical deepoxidation by dissolving metal reduction. 1984 J. Antibiot. pmid:6706848
Sakamoto M et al. Deepoxidation of 16-membered epoxyenone macrolide antibiotics. III. In vitro and in vivo evaluation of deepoxidation products of carbomycin A, deltamycin A1, 4"-phenylacetyldeltamycin, angolamycin and rosamicin. 1984 J. Antibiot. pmid:6706849
Dafwang II et al. Broiler chick growth response to antibiotics, 1981-1982. 1984 Poult. Sci. pmid:6610176
Omura S et al. Effect of ammonium ion, inorganic phosphate and amino acids on the biosynthesis of protylonolide, a precursor of tylosin aglycone. 1984 J. Antibiot. pmid:6735923
Baltz RH and Stonesifer J Phenotypic changes associated with loss of expression of tylosin biosynthesis and resistance genes in Streptomyces fradiae. 1985 J. Antibiot. pmid:4066505