| MeSH term | MeSH ID | Detail |
|---|---|---|
| Enterotoxemia | D004767 | 1 associated lipids |
| Bacillaceae Infections | D016863 | 1 associated lipids |
| Erysipelothrix Infections | D004889 | 1 associated lipids |
| Conjunctivitis, Viral | D003236 | 1 associated lipids |
| Bovine Respiratory Disease Complex | D048090 | 2 associated lipids |
| Primate Diseases | D018419 | 2 associated lipids |
| Pneumonia of Calves, Enzootic | D048089 | 2 associated lipids |
| Keratoconjunctivitis, Infectious | D007639 | 2 associated lipids |
| Pneumonia of Swine, Mycoplasmal | D045729 | 2 associated lipids |
| Pasteurellosis, Pneumonic | D012766 | 3 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- FEMS Microbiol. Lett. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lüthje P and Schwarz S | Molecular analysis of constitutively expressed erm(C) genes selected in vitro in the presence of the non-inducers pirlimycin, spiramycin and tylosin. | 2007 | J. Antimicrob. Chemother. | pmid:17085767 |
| Hu D and Coats JR | Aerobic degradation and photolysis of tylosin in water and soil. | 2007 | Environ. Toxicol. Chem. | pmid:17521133 |
| Song W et al. | Determination of amprolium, carbadox, monensin, and tylosin in surface water by liquid chromatography/tandem mass spectrometry. | 2007 | Rapid Commun. Mass Spectrom. | pmid:17510929 |
| Vincent U et al. | Validation of an analytical method for the determination of spiramycin, virginiamycin and tylosin in feeding-stuffs by thin-layer chromatography and bio-autography. | 2007 | Food Addit Contam | pmid:17454108 |
| Berrang ME et al. | Subtherapeutic tylosin phosphate in broiler feed affects Campylobacter on carcasses during processing. | 2007 | Poult. Sci. | pmid:17495097 |
| Korshunova GA et al. | [Peptide derivatives of tylosin-related macrolides]. | 2007 Mar-Apr | Bioorg. Khim. | pmid:17476984 |
| Ramlachan N et al. | A comparative study on the effects of tylosin on select bacteria during continuous flow culture of mixed populations of gut microflora derived from a feral and a domestic pig. | 2008 | Foodborne Pathog. Dis. | pmid:18260812 |
| Jacob ME et al. | Effects of feeding wet corn distillers grains with solubles with or without monensin and tylosin on the prevalence and antimicrobial susceptibilities of fecal foodborne pathogenic and commensal bacteria in feedlot cattle. | 2008 | J. Anim. Sci. | pmid:18192558 |
| Clark C et al. | Pharmacokinetics of tilmicosin in equine tissues and plasma. | 2008 | J. Vet. Pharmacol. Ther. | pmid:18177321 |
| Smith LK and Mankin AS | Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. | 2008 | Antimicrob. Agents Chemother. | pmid:18299405 |
| Aust MO et al. | Distribution of sulfamethazine, chlortetracycline and tylosin in manure and soil of Canadian feedlots after subtherapeutic use in cattle. | 2008 | Environ. Pollut. | pmid:18440678 |
| Douthwaite S et al. | Interaction of the tylosin-resistance methyltransferase RlmA II at its rRNA target differs from the orthologue RlmA I. | 2008 | J. Mol. Biol. | pmid:18406425 |
| Reuter RR et al. | Effects of dietary energy source and level and injection of tilmicosin phosphate on immune function in lipopolysaccharide-challenged beef steers. | 2008 | J. Anim. Sci. | pmid:18407986 |
| Hu D et al. | Identification of tylosin photoreaction products and comparison of ELISA and HPLC methods for their detection in water. | 2008 | Environ. Sci. Technol. | pmid:18497154 |
| Reynaldi FJ et al. | Effectiveness of tilmicosin against Paenibacillus larvae, the causal agent of American Foulbrood disease of honeybees. | 2008 | Vet. Microbiol. | pmid:18539412 |
| Mir PS et al. | Effects of dietary sunflower seeds and tylosin phosphate on production variables, carcass characteristics, fatty acid composition, and liver abscess incidence in crossbred steers. | 2008 | J. Anim. Sci. | pmid:18567724 |
| Nickell JS et al. | Comparison of short-term health and performance effects related to prophylactic administration of tulathromycin versus tilmicosin in long-hauled, highly stressed beef stocker calves. | 2008 | Vet. Ther. | pmid:18597253 |
| Chen J et al. | Technical note: Occurrence in fecal microbiota of genes conferring resistance to both macrolide-lincosamide-streptogramin B and tetracyclines concomitant with feeding of beef cattle with tylosin. | 2008 | J. Anim. Sci. | pmid:18469042 |
| Depenbusch BE et al. | Efficacy of monensin and tylosin in finishing diets based on steam-flaked corn with and without corn wet distillers grains with solubles. | 2008 | J. Anim. Sci. | pmid:18469059 |
| Shimada T et al. | Modelling the effect of the antimicrobial tylosin on the performance of an anaerobic sequencing batch reactor. | 2008 | Water Sci. Technol. | pmid:18547919 |
| Gallina G et al. | Acute toxicity evaluation of four antibacterials with Daphnia magna. | 2008 | Vet. Res. Commun. | pmid:18688742 |
| Stoev G and Nazarov V | Identification of the related substances of tilmicosin by liquid chromatography/ion trap mass spectrometry. | 2008 | Rapid Commun. Mass Spectrom. | pmid:18491285 |
| Achard A et al. | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. | 2008 | Antimicrob. Agents Chemother. | pmid:18519724 |
| Shimada T et al. | Inhibitory effects of the macrolide antimicrobial tylosin on anaerobic treatment. | 2008 | Biotechnol. Bioeng. | pmid:18646223 |
| Caldwell DB et al. | Development, stability, and molecular mechanisms of macrolide resistance in Campylobacter jejuni. | 2008 | Antimicrob. Agents Chemother. | pmid:18779354 |
| Giadinis ND et al. | Mortality in adult goats attributed to Mycoplasma capricolum subspecies capricolum. | 2008 | Vet. Rec. | pmid:18757908 |
| Parker KI et al. | Quarter-level analysis of subclinical and clinical mastitis in primiparous heifers following the use of a teat sealant or an injectable antibiotic, or both, precalving. | 2008 | J. Dairy Sci. | pmid:18096938 |
| Crespo R and McMillan R | Facial cellulitis induced in chickens by Mycoplasma gallisepticum bacterin and its treatment. | 2008 | Avian Dis. | pmid:19166067 |
| Van Donkersgoed J et al. | Comparative efficacy of tilmicosin versus tulathromycin as a metaphylactic antimicrobial in feedlot calves at moderate risk for respiratory disease. | 2008 | Vet. Ther. | pmid:19177334 |
| Lilia G et al. | Circadian serum concentrations of tylosin in broilers after feed or water medication. | 2008 | Br. Poult. Sci. | pmid:18836909 |
| Cundliffe E | Control of tylosin biosynthesis in Streptomyces fradiae. | 2008 | J. Microbiol. Biotechnol. | pmid:18852501 |
| Nathues H and grosse Beilage E | Diagnosis of Lawsonia intracellularis infection in pigs after vaccination or antimicrobial treatment. | 2008 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:19024547 |
| Oakes J and Seifert S | American association of poison control centers database characterization of human tilmicosin exposures, 2001-2005. | 2008 | J Med Toxicol | pmid:19031373 |
| Catry B et al. | Efficacy of metaphylactic florfenicol therapy during natural outbreaks of bovine respiratory disease. | 2008 | J. Vet. Pharmacol. Ther. | pmid:19000268 |
| Fricke JA et al. | Pharmacokinetics and tissue depletion of tilmicosin in turkeys. | 2008 | J. Vet. Pharmacol. Ther. | pmid:19000285 |
| Beltran-Alcrudo D et al. | A persistent outbreak of ulcerative enteritis in bobwhite quail (Colinus virginianus). | 2008 | Avian Dis. | pmid:18939648 |
| Weber TE and Kerr BJ | Effect of sodium butyrate on growth performance and response to lipopolysaccharide in weanling pigs. | 2008 | J. Anim. Sci. | pmid:17998428 |
| Pol-Hofstad I et al. | Collaborative study of a microbiological screening method (three-plate) for the banned antimicrobial growth promotors tylosin, virginiamycin, spiramycin, zinc bacitracin and avoparcin in animal feed. | 2008 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680856 |
| Blackwood RS et al. | Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta). | 2008 | Comp. Med. | pmid:19793461 |
| Demoling LA and Bååth E | No long-term persistence of bacterial pollution-induced community tolerance in tylosin-polluted soil. | 2008 | Environ. Sci. Technol. | pmid:18853809 |
| Castonguay R et al. | Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase. | 2008 | J. Am. Chem. Soc. | pmid:18693734 |
| Petropoulos AD et al. | Stepwise binding of tylosin and erythromycin to Escherichia coli ribosomes, characterized by kinetic and footprinting analysis. | 2008 | J. Biol. Chem. | pmid:18079110 |
| Akhter S et al. | Effect of antibiotics in extender on bacterial and spermatozoal quality of cooled buffalo (Bubalus bubalis) bull semen. | 2008 | Reprod. Domest. Anim. | pmid:18042206 |
| Bailey M et al. | Induction of erm(C) expression by noninducing antibiotics. | 2008 | Antimicrob. Agents Chemother. | pmid:18086834 |
| Diagnosis | pasteurellosis. | 2008 | Lab Anim (NY) | pmid:18094697 | |
| Wagner BA et al. | Effect of antimicrobial dosage regimen on Salmonella and Escherichia coli isolates from feeder swine. | 2008 | Appl. Environ. Microbiol. | pmid:18223115 |
| Kim MH et al. | Comparative pharmacokinetics of tylosin or florfenicol after a single intramuscular administration at two different doses of tylosin-florfenicol combination in pigs. | 2008 | J. Vet. Med. Sci. | pmid:18250580 |
| Angenent LT et al. | Effect of the presence of the antimicrobial tylosin in swine waste on anaerobic treatment. | 2008 | Water Res. | pmid:18258277 |
| Smith GW et al. | Elimination kinetics of tilmicosin following intramammary administration in lactating dairy cattle. | 2009 | J. Am. Vet. Med. Assoc. | pmid:19210246 |
| Kouvela EC et al. | Distinct mode of interaction of a novel ketolide antibiotic that displays enhanced antimicrobial activity. | 2009 | Antimicrob. Agents Chemother. | pmid:19164155 |
| Baggio A et al. | Residues of antibacterial drugs in honey from the Italian market. | 2009 | Food Addit Contam Part B Surveill | pmid:24784967 |
| Chemier JA et al. | Trends in microbial synthesis of natural products and biofuels. | 2009 | Adv. Enzymol. Relat. Areas Mol. Biol. | pmid:18990830 |
| Montgomery JL et al. | Effects of dietary zilpaterol hydrochloride on feedlot performance and carcass characteristics of beef steers fed with and without monensin and tylosin. | 2009 | J. Anim. Sci. | pmid:18997069 |
| Boles JA et al. | Growth implants reduced tenderness of steaks from steers and heifers with different genetic potentials for growth and marbling. | 2009 | J. Anim. Sci. | pmid:18791138 |
| Han C et al. | Hydrogenated castor oil nanoparticles as carriers for the subcutaneous administration of tilmicosin: in vitro and in vivo studies. | 2009 | J. Vet. Pharmacol. Ther. | pmid:19290940 |
| Engi H | [Perspectives of inhibition of multidrug resistance during cancer chemotherapy, in vitro and in vivo experiments]. | 2009 | Orv Hetil | pmid:19293063 |
| Hoese A et al. | Chlortetracycline and tylosin runoff from soils treated with antimicrobial containing manure. | 2009 | J Environ Sci Health B | pmid:19365753 |
| Meyer NF et al. | Effect of essential oils, tylosin, and monensin on finishing steer performance, carcass characteristics, liver abscesses, ruminal fermentation, and digestibility. | 2009 | J. Anim. Sci. | pmid:19359504 |
| Christodoulopoulos G | Adverse outcome of using tilmicosin in a lamb with multiple ventricular septal defects. | 2009 | Can. Vet. J. | pmid:19337615 |
| Khaliq S et al. | Production of tylosin in solid-state fermentation by Streptomyces fradiae NRRL-2702 and its gamma-irradiated mutant (gamma-1). | 2009 | Lett. Appl. Microbiol. | pmid:19780953 |
| Hu D and Coats JR | Laboratory evaluation of mobility and sorption for the veterinary antibiotic, tylosin, in agricultural soils. | 2009 | J Environ Monit | pmid:19724833 |
| Khalifeh MS et al. | Assessment of humoral and cellular-mediated immune response in chickens treated with tilmicosin, florfenicol, or enrofloxacin at the time of Newcastle disease vaccination. | 2009 | Poult. Sci. | pmid:19762865 |
| Guedes RM et al. | Use of tylvalosin-medicated feed to control porcine proliferative enteropathy. | 2009 | Vet. Rec. | pmid:19767637 |
| Fitzgerald J | Administration of micotil. | 2009 | Vet. Rec. | pmid:19767643 |
| Stone JJ et al. | Effect of antimicrobial compounds tylosin and chlortetracycline during batch anaerobic swine manure digestion. | 2009 | Water Res. | pmid:19695662 |
| Atef M et al. | Effect of albendazole administration on pharmacokinetic aspects of tylosin in lactating goats. | 2009 | Drug Metab Lett | pmid:19702546 |
| Hilton GG et al. | Effects of feeding zilpaterol hydrochloride with and without monensin and tylosin on carcass cutability and meat palatability of beef steers. | 2009 | J. Anim. Sci. | pmid:19028853 |
| Byrne-Bailey KG et al. | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. | 2009 | Antimicrob. Agents Chemother. | pmid:19064898 |
| Petropoulos AD et al. | Time-resolved binding of azithromycin to Escherichia coli ribosomes. | 2009 | J. Mol. Biol. | pmid:19071138 |
| Blackwell PA et al. | Effects of agricultural conditions on the leaching behaviour of veterinary antibiotics in soils. | 2009 | Chemosphere | pmid:19128817 |
| Chénier MR and Juteau P | Fate of chlortetracycline- and tylosin-resistant bacteria in an aerobic thermophilic sequencing batch reactor treating swine waste. | 2009 | Microb. Ecol. | pmid:19125305 |
| Liu F et al. | Effects of six selected antibiotics on plant growth and soil microbial and enzymatic activities. | 2009 | Environ. Pollut. | pmid:19157661 |
| Bodoor K et al. | Design and implementation of an ribonucleic acid (RNA) directed fragment library. | 2009 | J. Med. Chem. | pmid:19445516 |
| Hunter RP et al. | Letter to the editor. | 2009 | Br. Poult. Sci. | pmid:19904632 |
| Suchodolski JS et al. | The effect of the macrolide antibiotic tylosin on microbial diversity in the canine small intestine as demonstrated by massive parallel 16S rRNA gene sequencing. | 2009 | BMC Microbiol. | pmid:19799792 |
| Warner K et al. | Control of Ornithobacterium rhinotracheale in poultry. | 2009 | Vet. Rec. | pmid:19946131 |
| Hao H et al. | 23S rRNA mutation A2074C conferring high-level macrolide resistance and fitness cost in Campylobacter jejuni. | 2009 | Microb. Drug Resist. | pmid:19857128 |
| Khaliq S et al. | Change in colony morphology and kinetics of tylosin production after UV and gamma irradiation mutagenesis of Streptomyces fradiae NRRL-2702. | 2009 | Microbiol. Res. | pmid:17475458 |
| Sharma R et al. | Selected antimicrobial resistance during composting of manure from cattle administered sub-therapeutic antimicrobials. | 2009 Mar-Apr | J. Environ. Qual. | pmid:19202027 |
| Granja R et al. | Determination of erythromycin and tylosin residues in honey by LC/MS/MS. | 2009 May-Jun | J AOAC Int | pmid:19610392 |
| Muraina IA et al. | Antimycoplasmal activity of some plant species from northern Nigeria compared to the currently used therapeutic agent. | 2010 | Pharm Biol | pmid:20819025 |
| Stone JJ et al. | Tylosin and chlortetracycline effects during swine manure digestion: influence of sodium azide. | 2010 | Bioresour. Technol. | pmid:20728345 |
| Mazzilli M and Zecconi A | Assessment of epithelial cells' immune and inflammatory response to Staphylococcus aureus when exposed to a macrolide. | 2010 | J. Dairy Res. | pmid:20822561 |
| Juntunen P et al. | Antimicrobial resistance in Campylobacter coli selected by tylosin treatment at a pig farm. | 2010 | Vet. Microbiol. | pmid:20684867 |
| Scott BA et al. | Efficacy of tylosin tartrate on canine Staphylococcus intermedius isolates in vitro. | 2010 | Vet. Ther. | pmid:20960412 |
| Buret AG | Immuno-modulation and anti-inflammatory benefits of antibiotics: the example of tilmicosin. | 2010 | Can. J. Vet. Res. | pmid:20357951 |
| Cornick NA | Tylosin and chlorotetracycline decrease the duration of fecal shedding of E. coli O157:H7 by swine. | 2010 | Vet. Microbiol. | pmid:20018464 |
| Gallina G et al. | Kinetics and intrapulmonary disposition of tilmicosin after single and repeated oral bolus administrations to rabbits. | 2010 | Vet. Res. Commun. | pmid:20480234 |
| van der Grinten E et al. | Comparing the sensitivity of algal, cyanobacterial and bacterial bioassays to different groups of antibiotics. | 2010 | Chemosphere | pmid:20430416 |
| Cerdá RO et al. | Impact of the type of catheter on the absorption of tylvalosin (acetylvaleryltylosin) administered orally to broiler chickens. | 2010 | J. Vet. Pharmacol. Ther. | pmid:20444046 |
| Shakya T and Wright GD | Nucleotide selectivity of antibiotic kinases. | 2010 | Antimicrob. Agents Chemother. | pmid:20231391 |
| Liu YM et al. | Sensitive determination of tilmicosin, erythromycin ethylsuccinate and clindamycin by CE with electrochemiluminescence detection using azithromycin as internal standard and its applications. | 2010 | J Sep Sci | pmid:20235137 |
| Catania S et al. | Treatment of eggshell abnormalities and reduced egg production caused by Mycoplasma synoviae infection. | 2010 | Avian Dis. | pmid:20608549 |
| Alatrache A et al. | Tylosin abatement in water by photocatalytic process. | 2010 | Water Sci. Technol. | pmid:20651450 |
| Kaizerman JA et al. | Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20594845 |
| Peltier E et al. | Zinc-induced antibiotic resistance in activated sludge bioreactors. | 2010 | Water Res. | pmid:20537675 |
| Logue CM et al. | Repeated therapeutic dosing selects macrolide-resistant Campylobacter spp. in a turkey facility. | 2010 | J. Appl. Microbiol. | pmid:20497488 |
| Gyémánt N et al. | In vitro and in vivo multidrug resistance reversal activity by a Betti-base derivative of tylosin. | 2010 | Br. J. Cancer | pmid:20551959 |
| Starosta AL et al. | Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition. | 2010 | Chem. Biol. | pmid:20534348 |
| Giordano R et al. | Effect of a high dose of three antibiotics on the reproduction of a parthenogenetic strain of Folsomia candida (Isotomidae: Collembola). | 2010 | Environ. Entomol. | pmid:22127168 |