| MeSH term | MeSH ID | Detail |
|---|---|---|
| Asthma | D001249 | 52 associated lipids |
| Ataxia | D001259 | 20 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Bacteriuria | D001437 | 7 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Campylobacter Infections | D002169 | 13 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Clostridium Infections | D003015 | 5 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Conjunctivitis, Viral | D003236 | 1 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- J. Antimicrob. Chemother. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shryock TR et al. | Effect of bentonite incorporated in a feed ration with tilmicosin in the prevention of induced Mycoplasma gallisepticum airsacculitis in broiler chickens. | 1994 Jul-Sep | Avian Dis. | pmid:7832702 |
| Lu L et al. | Autoinducer 2-like activity in poultry-associated enteric bacteria in response to subtherapeutic antibiotic exposure. | 2005 | Avian Dis. | pmid:15839416 |
| Migaki TT et al. | Efficacy of danofloxacin and tylosin in the control of mycoplasmosis in chicks infected with tylosin-susceptible or tylosin-resistant field isolates of Mycoplasma gallisepticum. | 1993 Apr-Jun | Avian Dis. | pmid:8395803 |
| Tanner AC et al. | A comparison of danofloxacin and tylosin in the control of induced Mycoplasma gallisepticum infection in broiler chicks. | 1993 Apr-Jun | Avian Dis. | pmid:8395804 |
| Jordan FT and Horrocks BK | The minimum inhibitory concentration of tilmicosin and tylosin for mycoplasma gallisepticum and Mycoplasma synoviae and a comparison of their efficacy in the control of Mycoplasma gallisepticum infection in broiler chicks. | 1996 Apr-Jun | Avian Dis. | pmid:8790882 |
| Kempf I et al. | Efficacy of tilmicosin in the control of experimental Mycoplasma gallisepticum infection in chickens. | 1997 Oct-Dec | Avian Dis. | pmid:9454912 |
| Carpenter TE et al. | The effect of Mycoplasma meleagridis infection and egg dipping on the weight-gain performance of turkey poults. | 1982 Apr-Jun | Avian Dis. | pmid:7103888 |
| Mathers JJ et al. | Inhibition of resistance plasmid transfer in Escherichia coli by ionophores, chlortetracycline, bacitracin, and ionophore/antimicrobial combinations. | 2004 Apr-Jun | Avian Dis. | pmid:15283418 |
| Crespo R and McMillan R | Facial cellulitis induced in chickens by Mycoplasma gallisepticum bacterin and its treatment. | 2008 | Avian Dis. | pmid:19166067 |
| Beltran-Alcrudo D et al. | A persistent outbreak of ulcerative enteritis in bobwhite quail (Colinus virginianus). | 2008 | Avian Dis. | pmid:18939648 |
| Catania S et al. | Treatment of eggshell abnormalities and reduced egg production caused by Mycoplasma synoviae infection. | 2010 | Avian Dis. | pmid:20608549 |
| Jordan FT et al. | In vitro and in vivo comparisons of valnemulin, tiamulin, tylosin, enrofloxacin, and lincomycin/spectinomycin against Mycoplasma gallisepticum. | 1998 Oct-Dec | Avian Dis. | pmid:9876842 |
| Jordan FT et al. | The comparison of an aqueous preparation of tilmicosin with tylosin in the treatment of Mycoplasma gallisepticum infection of turkey poults. | 1999 Jul-Sep | Avian Dis. | pmid:10494422 |
| Nolan PM et al. | Maintenance of a captive flock of house finches free of infection by Mycoplasma gallisepticum. | 2000 Oct-Dec | Avian Dis. | pmid:11195652 |
| Skelly BJ et al. | Prophylactic efficacy of 3-acetyl-4''-isovaleryl tylosin in a Mycoplasma gallisepticum-induced airsacculitis infection. | 1986 Jul-Sep | Avian Dis. | pmid:3767811 |
| Cummings TS et al. | Effect of medicated feed on tracheal infection and population of Mycoplasma gallisepticum in chickens. | 1986 Jul-Sep | Avian Dis. | pmid:3767816 |
| Evans RD et al. | Field evaluation of tylosin premix in layers previously vaccinated with a live Mycoplasma gallisepticum vaccine. | 2002 Jan-Mar | Avian Dis. | pmid:11922337 |
| Cerdá RO et al. | In vitro antibiotic susceptibility of field isolates of Mycoplasma synoviae in Argentina. | 2002 Jan-Mar | Avian Dis. | pmid:11922338 |
| Wang C et al. | In vitro susceptibility of avian mycoplasmas to enrofloxacin, sarafloxacin, tylosin, and oxytetracycline. | 2001 Apr-Jun | Avian Dis. | pmid:11417828 |
| VoeÄkova TA et al. | [Bion-M1. Biological activities of microorganisms under the conditions of a 30-day space flight]. | 2014 | Aviakosm Ekolog Med | pmid:25365877 |
| Stephens CP et al. | In-vitro antibacterial properties of tilmicosin against Australian isolates of Pasteurella multocida and Pasteurella haemolytica from cattle. | 1993 | Aust. Vet. J. | pmid:8257321 |
| Blackall PJ et al. | In-vitro antibacterial properties of tilmicosin against Australian isolates of Pasteurella multocida and Actinobacillus pleuropneumoniae from pigs. | 1995 | Aust. Vet. J. | pmid:8787526 |
| Scott PR et al. | Use of tilmicosin in a severe outbreak of respiratory disease in weaned beef calves. | 1996 | Aust. Vet. J. | pmid:8660201 |
| Cusack PM | Effect of mass medication with antibiotics at feedlot entry on the health and growth rate of cattle destined for the Australian domestic market. | 2004 | Aust. Vet. J. | pmid:15088981 |
| Shiel MJ et al. | Polyarthritis in a calf associated with a group 7 Mycoplasma infection. | 1982 | Aust. Vet. J. | pmid:6892005 |
| Arzey GG and Arzey KE | Successful treatment of mycoplasmosis in layer chickens with single dose therapy. | 1992 | Aust. Vet. J. | pmid:1379426 |
| Smith SC et al. | In-vitro antimicrobial susceptibility of Australian isolates of Treponema hyodysenteriae. | 1991 | Aust. Vet. J. | pmid:1839652 |
| Buller NB and Hampson DJ | Antimicrobial susceptibility testing of Serpulina hyodysenteriae. | 1994 | Aust. Vet. J. | pmid:7945100 |
| Blackall PJ et al. | Minimal inhibitory concentration of tilmicosin against isolates of Histophilus somni from Australian cattle. | 2007 | Aust. Vet. J. | pmid:18042158 |
| Zuzulova M et al. | In vitro activity of tylosin and its derivatives against Ureaplasma urealyticum. | 1995 | Arzneimittelforschung | pmid:8929244 |
| Anti-infective drug use in relation to the risk of agranulocytosis and aplastic anemia. A report from the International Agranulocytosis and Aplastic Anemia Study. | 1989 | Arch. Intern. Med. | pmid:2785785 | |
| Kirchgessner M et al. | [The effect of avilamycin and tylosin on the apparent digestibility of iron, zinc, copper, manganese and selenium in the beginning and ending performance of swine]. | 1994 | Arch Tierernahr | pmid:7778980 |
| Kirchgessner M et al. | [Effect of avilamycin and tylosin on the metabolizable energy in growing and finishing pigs]. | 1995 | Arch Tierernahr | pmid:8526732 |
| Worseck M et al. | [Activity and minimal inhibitory concentration of turimycin against important pathogens in veterinary medicine]. | 1983 | Arch Exp Veterinarmed | pmid:6651443 |
| Hoffmann H et al. | [Antimicrobial activity in tissues of swine following subcutaneous administration of turimycin]. | 1983 | Arch Exp Veterinarmed | pmid:6651444 |
| Jung WS et al. | Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16493552 |
| Khaliq S et al. | Characterization of mutations in regulatory genes of Tyl cluster leading to overexpression of tylosin in mutant γ-1 of Streptomyces fradiae NRRL-2702. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24270892 |
| Arisawa A et al. | Cloning of the macrolide antibiotic biosynthesis gene acyA, which encodes 3-O-acyltransferase, from Streptomyces thermotolerans and its use for direct fermentative production of a hybrid macrolide antibiotic. | 1994 | Appl. Environ. Microbiol. | pmid:8074537 |
| Lee SH and Lee KJ | Aspartate aminotransferase and tylosin biosynthesis in Streptomyces fradiae. | 1993 | Appl. Environ. Microbiol. | pmid:8481008 |
| Jackson CR et al. | Effects of tylosin use on erythromycin resistance in enterococci isolated from swine. | 2004 | Appl. Environ. Microbiol. | pmid:15240302 |
| Amachawadi RG et al. | Occurrence of the transferable copper resistance gene tcrB among fecal enterococci of U.S. feedlot cattle fed copper-supplemented diets. | 2013 | Appl. Environ. Microbiol. | pmid:23666328 |
| Nagaraja TG and Taylor MB | Susceptibility and resistance of ruminal bacteria to antimicrobial feed additives. | 1987 | Appl. Environ. Microbiol. | pmid:3116929 |
| Yao RC and Mahoney DF | Enzyme immunoassay for macrolide antibiotics: characterization of an antibody to 23-amino-O-mycaminosyltylonolide. | 1989 | Appl. Environ. Microbiol. | pmid:2764563 |
| Wagner BA et al. | Effect of antimicrobial dosage regimen on Salmonella and Escherichia coli isolates from feeder swine. | 2008 | Appl. Environ. Microbiol. | pmid:18223115 |
| DENNY CB et al. | Effects of tylosin and nisin on canned food spoilage bacteria. | 1961 | Appl Microbiol | pmid:13721908 |
| Whitehead TR et al. | Savagea faecisuis gen. nov., sp. nov., a tylosin- and tetracycline-resistant bacterium isolated from a swine-manure storage pit. | 2015 | Antonie Van Leeuwenhoek | pmid:25980832 |
| Baltz RH et al. | Applications of transposition mutagenesis in antibiotic producing streptomycetes. | 1997 | Antonie Van Leeuwenhoek | pmid:9049029 |
| Cundliffe E et al. | The tylosin-biosynthetic genes of Streptomyces fradiae. | 2001 | Antonie Van Leeuwenhoek | pmid:11816964 |
| Andersen NM et al. | Inhibition of protein synthesis on the ribosome by tildipirosin compared with other veterinary macrolides. | 2012 | Antimicrob. Agents Chemother. | pmid:22926570 |
| Antunes NT et al. | In vitro susceptibilities of Mycoplasma putrefaciens field isolates. | 2007 | Antimicrob. Agents Chemother. | pmid:17638695 |