Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Asthma D001249 52 associated lipids
Ataxia D001259 20 associated lipids
Bacterial Infections D001424 21 associated lipids
Bacteriuria D001437 7 associated lipids
Body Weight D001835 333 associated lipids
Campylobacter Infections D002169 13 associated lipids
Cattle Diseases D002418 24 associated lipids
Clostridium Infections D003015 5 associated lipids
Colitis D003092 69 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Coleman MR et al. The need for larger analytical samples with granulated feed additives. 1993 Sep-Oct J AOAC Int pmid:8241822
Scott PR Field study of undifferentiated respiratory disease in housed beef calves. 1994 Vet. Rec. pmid:8203107
Chan W et al. Determination of tylosin and tilmicosin residues in animal tissues by reversed-phase liquid chromatography. 1994 Mar-Apr J AOAC Int pmid:8199468
Danese P et al. Occupational contact dermatitis from tylosin. 1994 Contact Derm. pmid:8187499
Coronato S et al. A simple method to eliminate mycoplasma from cell cultures. 1994 J. Virol. Methods pmid:8175949
Inouye M et al. Cloning and sequences of two macrolide-resistance-encoding genes from mycinamicin-producing Micromonospora griseorubida. 1994 Gene pmid:8163173
Tan ZL et al. Serum neutralizing antibodies against Fusobacterium necrophorum leukotoxin in cattle with experimentally induced or naturally developed hepatic abscesses. 1994 J. Anim. Sci. pmid:8157537
Wardlaw AC et al. Bactericidal activity in the pig roundworm Ascaris suum. 1994 J. Appl. Bacteriol. pmid:8144403
Hartman EG and Geryl J Comparison between the minimal inhibitory concentration of tilmicosin and oxytetracycline for bovine pneumonic Pasteurella haemolytica isolates. 1993 Vet Q pmid:8122359
Fodor L et al. Treatment of calf pneumonia with tilmicosin. 1993 Acta Vet. Hung. pmid:8116500
Arisawa A et al. Cloning of the macrolide antibiotic biosynthesis gene acyA, which encodes 3-O-acyltransferase, from Streptomyces thermotolerans and its use for direct fermentative production of a hybrid macrolide antibiotic. 1994 Appl. Environ. Microbiol. pmid:8074537
Riddell KP et al. Antibiotic treatment of bovine embryos. 1993 J. Assist. Reprod. Genet. pmid:8069094
Narandja A et al. Structure-activity relationship among polyhydro derivatives of tylosin. 1994 J. Antibiot. pmid:8040056
Kounenis G et al. Comparative study of erythromycin, troleandomycin and tylosin on the rabbit intestine. 1994 Fundam Clin Pharmacol pmid:8020874
Duff GC et al. Effects of lasalocid and monensin plus tylosin on serum metabolic hormones and clinical chemistry profiles of beef steers fed a 90% concentrate diet. 1994 J. Anim. Sci. pmid:8014140
Scott DW et al. Efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. 1994 Can. Vet. J. pmid:7994702
Trovatelli LD et al. The effect of some antibiotics on Enterococcus faecium SF 68 inoculated in germ-free mice. 1994 Microbiol. Res. pmid:7987613
Merson-Davies LA and Cundliffe E Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome. 1994 Mol. Microbiol. pmid:7984112
McGuigan MA Human exposures to tilmicosin (MICOTIL). 1994 Vet Hum Toxicol pmid:7975134
Buller NB and Hampson DJ Antimicrobial susceptibility testing of Serpulina hyodysenteriae. 1994 Aust. Vet. J. pmid:7945100
Tang L et al. Amino acid catabolism and antibiotic synthesis: valine is a source of precursors for macrolide biosynthesis in Streptomyces ambofaciens and Streptomyces fradiae. 1994 J. Bacteriol. pmid:7928973
Kageyama S and Tsuchiya T Synthesis of 2-C-methyl derivatives of 3,4'-dideoxymycaminosyltylonolide, a novel type of 16-membered macrolide antibiotic. 1994 J. Antibiot. pmid:7928687
Delepine B et al. Identification of tylosin in bovine muscle at the maximum residue limit level by liquid chromatography-mass spectrometry, using a particle beam interface. 1994 Analyst pmid:7879883
Parker RM and Patel RK Determination of tilmicosin in ovine milk using high-performance liquid chromatography. 1994 Analyst pmid:7879857
Caraffini S et al. Tylosin, an airborne contact allergen in veterinarians. 1994 Contact Derm. pmid:7867337
Inamoto T et al. Antibacterial activity of tilmicosin against Pasteurella multocida and Actinobacillus pleuropneumoniae isolated from pneumonic lesions in swine. 1994 J. Vet. Med. Sci. pmid:7865594
Ueda Y et al. Effect of terdecamycin on experimentally induced Mycoplasma hyopneumoniae-infection in pigs. 1994 Zentralblatt Veterinarmedizin Reihe B pmid:7839749
Shryock TR et al. Effect of bentonite incorporated in a feed ration with tilmicosin in the prevention of induced Mycoplasma gallisepticum airsacculitis in broiler chickens. 1994 Jul-Sep Avian Dis. pmid:7832702
Kirchgessner M et al. [The effect of avilamycin and tylosin on the apparent digestibility of iron, zinc, copper, manganese and selenium in the beginning and ending performance of swine]. 1994 Arch Tierernahr pmid:7778980
Nguyen LT et al. The tylosin producer, Streptomyces fradiae, contains a second valine dehydrogenase. 1995 Microbiology (Reading, Engl.) pmid:7773408
Lee SH and Lee KJ Kinetics of the repression of tylosin biosynthesis by ammonium ion in Streptomyces fradiae. 1994 J. Biotechnol. pmid:7764561
Arisawa A et al. Cloning and nucleotide sequences of two genes involved in the 4''-O-acylation of macrolide antibiotics from Streptomyces thermotolerans. 1993 Biosci. Biotechnol. Biochem. pmid:7764361
Paesen J et al. Isolation of decomposition products of tylosin using liquid chromatography. 1995 J Chromatogr A pmid:7757214
pmid:7756878
Narandja A et al. 10,11,12,13-Tetrahydro derivatives of tylosin. II. Synthesis, antibacterial activity and tissue of 4'-deoxy-10,11,12,13-tetrahydrodesmycosin. 1995 J. Antibiot. pmid:7730160
Shryock TR et al. Proposed quality control guidelines for antimicrobial susceptibility tests using tilmicosin. 1995 J. Clin. Microbiol. pmid:7714188
Galyean ML et al. Effects of arrival medication with tilmicosin phosphate on health and performance of newly received beef cattle. 1995 J. Anim. Sci. pmid:7665351
Creemer LC et al. Synthesis, antimicrobial activity and in vivo fluorine NMR of a hexafluorinated derivative of tilmicosin. 1995 J. Antibiot. pmid:7649867
Bobillot S et al. Chemical modification of tylosin. 1995 J. Antibiot. pmid:7649866
Stock RA et al. Effect of monensin and monensin and tylosin combination on feed intake variation of feedlot steers. 1995 J. Anim. Sci. pmid:7601752
Harvey RB et al. Influence of the antibiotics lincomycin and tylosin on aflatoxicosis when added to aflatoxin-contaminated diets of growing swine. 1995 J. Vet. Diagn. Invest. pmid:7578454
Kelemen GH et al. Transcriptional attenuation control of the tylosin-resistance gene tlrA in Streptomyces fradiae. 1994 Mol. Microbiol. pmid:7534372
Omura S et al. X-ray crystallography of protylonolide and absolute configuration of tylosin. 1980 J. Antibiot. pmid:7429997
Inouye S et al. Modifications of a macrolide antibiotic midecamycin. II. Reaction of midecamycin and 9-acetylmidecamycin with dimethylsulfoxide and acetic anhydride. 1980 J. Antibiot. pmid:7372551
Allan EM and Pirie HM In vitro activity of tiamulin against bovine respiratory tract mycoplasmas. 1981 Res. Vet. Sci. pmid:7323463
Tanaka A et al. Syntheses of 4'-deoxy-demycarosyl tylosin and its analogues. 1981 J. Antibiot. pmid:7309635
Tanaka A et al. Syntheses of derivatives of 4'-deoxymycaminosyl tylonolide and mycaminosyl tylonolide modified AT C-23. 1981 J. Antibiot. pmid:7309634
Tanaka A et al. Synthesis of 4'-deoxymycaminosyl tylonolide. 1981 J. Antibiot. pmid:7309633
Seno ET and Baltz RH Properties of S-adenosyl-L-methionine:macrocin O-methyltransferase in extracts of Streptomyces fradiae strains which produce normal or elevated levels of tylosin and in mutants blocked in specific O-methylations. 1981 Antimicrob. Agents Chemother. pmid:7305323
Tsuchiya M et al. Studies on the effects of 3-acetyl-4"-isovaleryltylosin against multiple-drug resistant strains of Staphylococcus aureus. 1981 J. Antibiot. pmid:7275812