Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Digital Dermatitis D058066 3 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Whitehead TR and Cotta MA Sequence analyses of a broad host-range plasmid containing ermT from a tylosin-resistant Lactobacillus sp. Isolated from swine feces. 2001 Curr. Microbiol. pmid:11375658
Lee SW et al. Prevalence of porcine proliferative enteropathy and its control with tylosin in Korea. 2001 J. Vet. Sci. pmid:12441690
Alt DP et al. Evaluation of antibiotics for treatment of cattle infected with Leptospira borgpetersenii serovar hardjo. 2001 J. Am. Vet. Med. Assoc. pmid:11549093
Draisci R et al. Confirmatory method for macrolide residues in bovine tissues by micro-liquid chromatography-tandem mass spectrometry. 2001 J Chromatogr A pmid:11554423
Naccari F et al. Effectiveness and kinetic behaviour of tilmicosin in the treatment of respiratory infections in sheep. 2001 Vet. Rec. pmid:11465263
Mateusen B et al. A comparative study of the preventive use of tilmicosin phosphate (Pulmotil premix) and Mycoplasma hyopneumoniae vaccination in a pig herd with chronic respiratory disease. 2001 J. Vet. Med. B Infect. Dis. Vet. Public Health pmid:11846018
Nolan PM et al. Maintenance of a captive flock of house finches free of infection by Mycoplasma gallisepticum. 2000 Oct-Dec Avian Dis. pmid:11195652
Stobba-Wiley CM and Readnour RS Determination of tilmicosin residues in cow and sheep milk by liquid chromatography. 2000 May-Jun J AOAC Int pmid:10868576
Stobba-Wiley CM et al. Determination of tilmicosin residues in chicken, cattle, swine, and sheep tissues by liquid chromatography. 2000 Jul-Aug J AOAC Int pmid:10995110
Bate N et al. The mycarose-biosynthetic genes of Streptomyces fradiae, producer of tylosin. 2000 Microbiology (Reading, Engl.) pmid:10658660
Ayling RD et al. Comparison of in vitro activity of danofloxacin, florfenicol, oxytetracycline, spectinomycin and tilmicosin against Mycoplasma mycoides subspecies mycoides small colony type. 2000 Vet. Rec. pmid:10737293
Fouces R et al. Conjugation and transformation of Streptomyces species by tylosin resistance. 2000 FEMS Microbiol. Lett. pmid:10802191
Frank GH et al. Effects of tilmicosin treatment on Pasteurella haemolytica organisms in nasal secretion specimens of calves with respiratory tract disease. 2000 Am. J. Vet. Res. pmid:10803647
Croft A et al. The effect of tilmicosin administered to ewes prior to lambing on incidence of clinical mastitis and subsequent lamb performance. 2000 Can. Vet. J. pmid:10769768
Pai MP et al. Macrolide drug interactions: an update. 2000 Ann Pharmacother pmid:10772438
Köhler B et al. Antibacterials that are used as growth promoters in animal husbandry can affect the release of Shiga-toxin-2-converting bacteriophages and Shiga toxin 2 from Escherichia coli strains. 2000 Microbiology (Reading, Engl.) pmid:10832635
Gaisser S et al. A defined system for hybrid macrolide biosynthesis in Saccharopolyspora erythraea. 2000 Mol. Microbiol. pmid:10792725
DeRosa DC et al. In vitro susceptibility of porcine respiratory pathogens to tilmicosin. 2000 J. Vet. Diagn. Invest. pmid:11108454
Fajt VR et al. Effects of danofloxacin and tilmicosin on circulating neutrophils in beef heifers. 2000 J. Vet. Pharmacol. Ther. pmid:11110107
Poulsen SM et al. Inhibition of the ribosomal peptidyl transferase reaction by the mycarose moiety of the antibiotics carbomycin, spiramycin and tylosin. 2000 J. Mol. Biol. pmid:11090288
Goubau S et al. Tilmicosin does not inhibit interleukin-8 gene expression in the bovine lung experimentally infected with Mannheimia (Pasteurella) haemolytica. 2000 Can. J. Vet. Res. pmid:11041503
Doak GA Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. 2000 Theriogenology pmid:10990358
Kim S Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. 2000 Theriogenology pmid:10990359
Rosenbusch RF Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. 2000 Theriogenology pmid:10990360
Thomas CB Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. 2000 Theriogenology pmid:10990361
Chin AC et al. Tilmicosin induces apoptosis in bovine peripheral neutrophils in the presence or in the absence of Pasteurella haemolytica and promotes neutrophil phagocytosis by macrophages. 2000 Antimicrob. Agents Chemother. pmid:10952596
Dinos GP and Kalpaxis DL Kinetic studies on the interaction between a ribosomal complex active in peptide bond formation and the macrolide antibiotics tylosin and erythromycin. 2000 Biochemistry pmid:10995229
Ayling RD et al. Comparison of in vitro activity of danofloxacin, florfenicol, oxytetracycline, spectinomycin and tilmicosin against recent field isolates of Mycoplasma bovis. 2000 Vet. Rec. pmid:10909906
Rabølle M and Spliid NH Sorption and mobility of metronidazole, olaquindox, oxytetracycline and tylosin in soil. 2000 Chemosphere pmid:10705549
Baguer AJ et al. Effects of the antibiotics oxytetracycline and tylosin on soil fauna. 2000 Chemosphere pmid:10705553
Loke ML et al. Stability of Tylosin A in manure containing test systems determined by high performance liquid chromatography. 2000 Chemosphere pmid:10705554
Vissiennon T et al. Effect of avilamycin, tylosin and ionophore anticoccidials on Clostridium perfringens enterotoxaemia in chickens. 2000 Berl. Munch. Tierarztl. Wochenschr. pmid:10684178
Duff GC et al. Effects of preshipping vs. arrival medication with tilmicosin phosphate and feeding chlortetracycline on health and performance of newly received beef cattle. 2000 J. Anim. Sci. pmid:10709916
Fodor L et al. Efficacy evaluations of the use of oral tilmicosin in pneumonic calves. 2000 Vet. J. pmid:10712808
Mackie DP et al. Mixed mycoplasma mastitis outbreak in a dairy herd. 2000 Vet. Rec. pmid:11058024
Halling-Sørensen B Algal toxicity of antibacterial agents used in intensive farming. 2000 Chemosphere pmid:10705551
Frank GH and Duff GC Effects of tilmicosin phosphate, administered prior to transport or at time of arrival, and feeding of chlortetracycline, after arrival in a feedlot, on Mannheimia haemolytica in nasal secretions of transported steers. 2000 Am. J. Vet. Res. pmid:11131584
Juhel-Gaugain M et al. Multiresidue chromatographic method for the determination of macrolide residues in muscle by high-performance liquid chromatography with UV detection. 1999 Sep-Oct J AOAC Int pmid:10513006
Dudriková E et al. Liquid chromatographic determination of tylosin in mastitic cow's milk following therapy. 1999 Nov-Dec J AOAC Int pmid:10589481
Jordan FT et al. The comparison of an aqueous preparation of tilmicosin with tylosin in the treatment of Mycoplasma gallisepticum infection of turkey poults. 1999 Jul-Sep Avian Dis. pmid:10494422
Davies R and Roberts TA Antimicrobial susceptibility of enterococci recovered from commercial swine carcasses: effect of feed additives. 1999 Lett. Appl. Microbiol. pmid:10664974
Short CR Comparative pharmacokinetics--sorting the sheep from the goats. 1999 Vet. J. pmid:10558834
Taha AA et al. Disposition kinetics of tylosin administered intravenously and intramuscularly in desert sheep and Nubian goats. 1999 Vet. J. pmid:10558841
Baltadzhieva D et al. [Analysis of immunological indices of occupational sensibilization to tylosin]. 1999 Med Tr Prom Ekol pmid:10605285
Visser IJ et al. Failure of antibiotics gentamycin, tylosin, lincomycin and spectinomycin to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. 1999 Theriogenology pmid:10728994
Crown LA and Smith RB Accidental veterinary antibiotic injection into a farm worker. 1999 Tenn Med pmid:10474305
Atef M et al. Elimination of tilmicosin in lactating ewes. 1999 DTW. Dtsch. Tierarztl. Wochenschr. pmid:10481373
Tobback K et al. Micellar electrokinetic capillary chromatography of macrolide antibiotics. Separation of tylosin, erythromycin and their related substances. 1999 J Chromatogr A pmid:10536850
Bate N et al. Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae. 1999 Chem. Biol. pmid:10467127
Nagaraja TG et al. Effects of tylosin on concentrations of Fusobacterium necrophorum and fermentation products in the rumen of cattle fed a high-concentrate diet. 1999 Am. J. Vet. Res. pmid:10490072