| MeSH term | MeSH ID | Detail |
|---|---|---|
| Digital Dermatitis | D058066 | 3 associated lipids |
| Bovine Respiratory Disease Complex | D048090 | 2 associated lipids |
| Pneumonia of Calves, Enzootic | D048089 | 2 associated lipids |
| Desulfovibrionaceae Infections | D045824 | 5 associated lipids |
| Pneumonia of Swine, Mycoplasmal | D045729 | 2 associated lipids |
| Porcine Reproductive and Respiratory Syndrome | D019318 | 4 associated lipids |
| Primate Diseases | D018419 | 2 associated lipids |
| Pneumonia, Bacterial | D018410 | 16 associated lipids |
| Neisseriaceae Infections | D016870 | 3 associated lipids |
| Ureaplasma Infections | D016869 | 5 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Appl. Environ. Microbiol. (2)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jacob ME et al. | Effects of feeding wet corn distillers grains with solubles with or without monensin and tylosin on the prevalence and antimicrobial susceptibilities of fecal foodborne pathogenic and commensal bacteria in feedlot cattle. | 2008 | J. Anim. Sci. | pmid:18192558 |
| Clark C et al. | Pharmacokinetics of tilmicosin in equine tissues and plasma. | 2008 | J. Vet. Pharmacol. Ther. | pmid:18177321 |
| Parker KI et al. | Quarter-level analysis of subclinical and clinical mastitis in primiparous heifers following the use of a teat sealant or an injectable antibiotic, or both, precalving. | 2008 | J. Dairy Sci. | pmid:18096938 |
| Diagnosis | pasteurellosis. | 2008 | Lab Anim (NY) | pmid:18094697 | |
| Bailey M et al. | Induction of erm(C) expression by noninducing antibiotics. | 2008 | Antimicrob. Agents Chemother. | pmid:18086834 |
| Petropoulos AD et al. | Stepwise binding of tylosin and erythromycin to Escherichia coli ribosomes, characterized by kinetic and footprinting analysis. | 2008 | J. Biol. Chem. | pmid:18079110 |
| Murphy MW et al. | Airborne antibiotic concentrations in a swine feeding operation. | 2007 | J Agric Saf Health | pmid:18075012 |
| Nouri M and Constable PD | Effect of parenteral administration of erythromycin, tilmicosin, and tylosin on abomasal emptying rate in suckling calves. | 2007 | Am. J. Vet. Res. | pmid:18052746 |
| Choi D et al. | Tylosin production by Streptomyces fradiae using raw cornmeal in airlift bioreactor. | 2007 | J. Microbiol. Biotechnol. | pmid:18051315 |
| Akhter S et al. | Effect of antibiotics in extender on bacterial and spermatozoal quality of cooled buffalo (Bubalus bubalis) bull semen. | 2008 | Reprod. Domest. Anim. | pmid:18042206 |
| Blackall PJ et al. | Minimal inhibitory concentration of tilmicosin against isolates of Histophilus somni from Australian cattle. | 2007 | Aust. Vet. J. | pmid:18042158 |
| Lawrence K | Micotil: safe use and administration. | 2007 | Vet. Rec. | pmid:18037699 |
| Nakura H et al. | Formation of an antibacterial metabolite from a new macrolide compound 23-O-benzyl-5-mycaminosyl-tylonolide (TMC-101), by a hepatic microsomal drug-metabolizing enzyme system. | 1991 | J. Pharmacobio-dyn. | pmid:1802985 |
| Weber TE and Kerr BJ | Effect of sodium butyrate on growth performance and response to lipopolysaccharide in weanling pigs. | 2008 | J. Anim. Sci. | pmid:17998428 |
| Boissevain I | [Punishment after the fact]. | 2007 | Tijdschr Diergeneeskd | pmid:17939495 |
| Booker CW et al. | Evaluation of the efficacy of tulathromycin as a metaphylactic antimicrobial in feedlot calves. | 2007 | Vet. Ther. | pmid:17926304 |
| Atef M et al. | Disposition of tylosin in goats. | 1991 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:1790764 |
| Lee SH and Lee KJ | Relationship between threonine dehydratase and biosynthesis of tylosin in Streptomyces fradiae. | 1991 | J. Gen. Microbiol. | pmid:1783901 |
| Ladely SR et al. | Development of macrolide-resistant Campylobacter in broilers administered subtherapeutic or therapeutic concentrations of tylosin. | 2007 | J. Food Prot. | pmid:17803155 |
| Sassman SA et al. | Sorption of tylosin A, D, and A-aldol and degradation of tylosin A in soils. | 2007 | Environ. Toxicol. Chem. | pmid:17702335 |
| Rezanka T et al. | Isobutyrate as a precursor of n-butyrate in the biosynthesis of tylosine and fatty acids. | 1991 | FEMS Microbiol. Lett. | pmid:1769552 |
| Xie W et al. | [Determination of five macrolide antibiotic residues in royal jelly samples by using high performance liquid chromatography tandem mass spectrometry]. | 2007 | Se Pu | pmid:17679440 |
| Werner JJ et al. | Environmental photochemistry of tylosin: efficient, reversible photoisomerization to a less-active isomer, followed by photolysis. | 2007 | J. Agric. Food Chem. | pmid:17655244 |
| Antunes NT et al. | In vitro susceptibilities of Mycoplasma putrefaciens field isolates. | 2007 | Antimicrob. Agents Chemother. | pmid:17638695 |
| Herrera M et al. | Quantitative determination of tilmicosin in canine serum by high performance liquid chromatography-tandem mass spectrometry. | 2007 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:17627909 |
| Nagaraja TG and Lechtenberg KF | Liver abscesses in feedlot cattle. | 2007 | Vet. Clin. North Am. Food Anim. Pract. | pmid:17606156 |
| Tikhomirova LA et al. | [Cytomorphological and cultural characteristics of tylosin-producing strains with different antibiotic activity]. | 1991 | Antibiot. Khimioter. | pmid:1755702 |
| Hu D and Coats JR | Aerobic degradation and photolysis of tylosin in water and soil. | 2007 | Environ. Toxicol. Chem. | pmid:17521133 |
| Song W et al. | Determination of amprolium, carbadox, monensin, and tylosin in surface water by liquid chromatography/tandem mass spectrometry. | 2007 | Rapid Commun. Mass Spectrom. | pmid:17510929 |
| Berrang ME et al. | Subtherapeutic tylosin phosphate in broiler feed affects Campylobacter on carcasses during processing. | 2007 | Poult. Sci. | pmid:17495097 |
| Korshunova GA et al. | [Peptide derivatives of tylosin-related macrolides]. | 2007 Mar-Apr | Bioorg. Khim. | pmid:17476984 |
| Khaliq S et al. | Change in colony morphology and kinetics of tylosin production after UV and gamma irradiation mutagenesis of Streptomyces fradiae NRRL-2702. | 2009 | Microbiol. Res. | pmid:17475458 |
| Vincent U et al. | Validation of an analytical method for the determination of spiramycin, virginiamycin and tylosin in feeding-stuffs by thin-layer chromatography and bio-autography. | 2007 | Food Addit Contam | pmid:17454108 |
| Thompson TS et al. | Degradation of incurred tylosin to desmycosin--implications for residue analysis of honey. | 2007 | Anal. Chim. Acta | pmid:17386728 |
| Kart A et al. | The possible protective effect of L-carnitine on tilmicosin-induced cardiotoxicity in mice. | 2007 | J Vet Med A Physiol Pathol Clin Med | pmid:17381679 |
| Litterio NJ et al. | Microbiological screening test validation for detection of tylosin excretion in milk of cows with low and high somatic cell counts. | 2007 | J Vet Med A Physiol Pathol Clin Med | pmid:17359452 |
| Lin J et al. | Effect of macrolide usage on emergence of erythromycin-resistant Campylobacter isolates in chickens. | 2007 | Antimicrob. Agents Chemother. | pmid:17353243 |
| González de la Huebra MJ et al. | Sample preparation strategy for the simultaneous determination of macrolide antibiotics in animal feedingstuffs by liquid chromatography with electrochemical detection (HPLC-ECD). | 2007 | J Pharm Biomed Anal | pmid:17257795 |
| McDougall S et al. | Parenteral treatment of clinical mastitis with tylosin base or penethamate hydriodide in dairy cattle. | 2007 | J. Dairy Sci. | pmid:17235155 |
| Abu-Basha EA et al. | Pharmacokinetics of tilmicosin (Provitil powder and Pulmotil liquid AC) oral formulations in chickens. | 2007 | Vet. Res. Commun. | pmid:17225089 |
| Elkins CA and Mullis LB | Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. | 2007 | Antimicrob. Agents Chemother. | pmid:17210767 |
| Blackwell PA et al. | The dissipation and transport of veterinary antibiotics in a sandy loam soil. | 2007 | Chemosphere | pmid:17204303 |
| Bignell DR et al. | Regulation of tylosin production: role of a TylP-interactive ligand. | 2007 | Mol. Microbiol. | pmid:17181783 |
| Couper A et al. | Treatment of pneumonia in pigs with long-acting injectable tylosin. | 2006 | Vet. Rec. | pmid:17158711 |
| Veenhuizen MF et al. | Analysis of reports of human exposure to Micotil 300 (tilmicosin injection). | 2006 | J. Am. Vet. Med. Assoc. | pmid:17144818 |
| Hamscher G et al. | Quantitative analysis of tylosin in eggs by high performance liquid chromatography with electrospray ionization tandem mass spectrometry: residue depletion kinetics after administration via feed and drinking water in laying hens. | 2006 | J. Agric. Food Chem. | pmid:17117786 |
| Hue KK and Bechhofer DH | Effect of ermC leader region mutations on induced mRNA stability. | 1991 | J. Bacteriol. | pmid:1711026 |
| Kim D et al. | In vitro susceptibilities of Leptospira spp. and Borrelia burgdorferi isolates to amoxicillin, tilmicosin, and enrofloxacin. | 2006 | J. Vet. Sci. | pmid:17106227 |
| Szczepanowski R et al. | Novel macrolide resistance module carried by the IncP-1beta resistance plasmid pRSB111, isolated from a wastewater treatment plant. | 2007 | Antimicrob. Agents Chemother. | pmid:17101677 |
| Lüthje P and Schwarz S | Molecular analysis of constitutively expressed erm(C) genes selected in vitro in the presence of the non-inducers pirlimycin, spiramycin and tylosin. | 2007 | J. Antimicrob. Chemother. | pmid:17085767 |