| MeSH term | MeSH ID | Detail |
|---|---|---|
| Digital Dermatitis | D058066 | 3 associated lipids |
| Bovine Respiratory Disease Complex | D048090 | 2 associated lipids |
| Pneumonia of Calves, Enzootic | D048089 | 2 associated lipids |
| Desulfovibrionaceae Infections | D045824 | 5 associated lipids |
| Pneumonia of Swine, Mycoplasmal | D045729 | 2 associated lipids |
| Porcine Reproductive and Respiratory Syndrome | D019318 | 4 associated lipids |
| Primate Diseases | D018419 | 2 associated lipids |
| Pneumonia, Bacterial | D018410 | 16 associated lipids |
| Neisseriaceae Infections | D016870 | 3 associated lipids |
| Ureaplasma Infections | D016869 | 5 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Moats WA et al. | Comparison of liquid chromatographic and bioassay procedures for determining depletion of intramuscularly injected tylosin. | 1985 May-Jun | J Assoc Off Anal Chem | pmid:4019360 |
| Itoh Z et al. | Structure-activity relation among macrolide antibiotics in initiation of interdigestive migrating contractions in the canine gastrointestinal tract. | 1985 | Am. J. Physiol. | pmid:3976891 |
| Goodwin RF | In vitro activity of tiamulin against porcine mycoplasmas. | 1985 | Res. Vet. Sci. | pmid:3975477 |
| Kietzmann M | [Comparative study of the distribution and excretion of tylosin of various origins]. | 1985 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:3899580 |
| Tsuzuki K et al. | Syntheses and antimicrobial activities of 9-O-acyl derivatives of tylosin and demycarosyltylosin. | 1986 | J. Antibiot. | pmid:3818453 |
| Jacks TM et al. | 3-Acetyl-4''-isovaleryl tylosin for prevention of swine dysentery. | 1986 | Am. J. Vet. Res. | pmid:3789492 |
| Cummings TS et al. | Effect of medicated feed on tracheal infection and population of Mycoplasma gallisepticum in chickens. | 1986 Jul-Sep | Avian Dis. | pmid:3767816 |
| Skelly BJ et al. | Prophylactic efficacy of 3-acetyl-4''-isovaleryl tylosin in a Mycoplasma gallisepticum-induced airsacculitis infection. | 1986 Jul-Sep | Avian Dis. | pmid:3767811 |
| Burrows GE et al. | Antibiotic disposition in experimental pneumonic pasteurellosis: gentamicin and tylosin. | 1986 | Can. J. Vet. Res. | pmid:3756673 |
| Tanaka Y et al. | Mechanism of nitrogen regulation of protylonolide biosynthesis in Streptomyces fradiae. | 1986 | J. Antibiot. | pmid:3733529 |
| Effect of space allowance and tylosin feeding on performance of growing-finishing pigs. NCR-89 Committee on Confinement Management of Swine. | 1986 | J. Anim. Sci. | pmid:3710927 | |
| Fish BJ and Carr GP | Pharmacopoeial procedure for the determination of tylosin factors by high-performance liquid chromatography. | 1986 | J. Chromatogr. | pmid:3700523 |
| Takeuchi T et al. | 4''-O-(4-methoxyphenyl)-acetyltylosin, a new macrolide derivative of therapeutic importance. | 1987 | J. Antibiot. | pmid:3680047 |
| Kiyoshima K et al. | New tylosin analogs produced by mutants of Streptomyces fradiae. | 1987 | J. Antibiot. | pmid:3680024 |
| Vancura A et al. | Fatty acids and production of tylosin-like compounds in Streptomyces fradiae. | 1987 | J. Basic Microbiol. | pmid:3625475 |
| Ball HJ and McCaughey WJ | Experimental intramuscular inoculation of tylosin in the elimination of ureaplasmas from ewes. | 1987 | Vet. Rec. | pmid:3617407 |
| Greer RT and Ryoo JP | Development of ocular inserts for cattle. | 1987 | Scanning Microsc. | pmid:3616580 |
| Westerbeek JA and Jaartsveld FH | [Mycoplasma infection on a cattle farm]. | 1987 | Tijdschr Diergeneeskd | pmid:3603536 |
| Wiley PF et al. | Enzymatic phosphorylation of macrolide antibiotics. | 1987 | J. Antibiot. | pmid:3570968 |
| Ose EE | In vitro antibacterial properties of EL-870, a new semi-synthetic macrolide antibiotic. | 1987 | J. Antibiot. | pmid:3570967 |
| el-Sayed MG et al. | Pharmacokinetic profile of tylosin in mastitic cows. | 1986 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:3530702 |
| Fishman SE et al. | Cloning genes for the biosynthesis of a macrolide antibiotic. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3479787 |
| Stonesifer J et al. | High frequency conjugal transfer of tylosin genes and amplifiable DNA in Streptomyces fradiae. | 1986 | Mol. Gen. Genet. | pmid:3458997 |
| Stipkovits L et al. | In vitro testing of the anti-mycoplasma effect of some anti-coccidial drugs. | 1987 | Vet. Microbiol. | pmid:3439016 |
| Blaha T et al. | Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme. | 1987 | Vet. Rec. | pmid:3424604 |
| Kirst HA et al. | In vitro and in vivo evaluation of C-20- and C-23-modified derivatives of tylosin against veterinary pathogens. | 1988 | J. Antibiot. | pmid:3417566 |
| Kirst HA et al. | Synthesis and evaluation of tylosin-related macrolides modified at the aldehyde function: a new series of orally effective antibiotics. | 1988 | J. Med. Chem. | pmid:3398001 |
| de Zwart MA et al. | Synthesis and copper-dependent antimycoplasmal activity of 1-amino-3-(2-pyridyl)isoquinoline derivatives. 1. Amides. | 1988 | J. Med. Chem. | pmid:3351847 |
| Gershon P and Howells RE | Synergy of four macrolide antibiotics with chloroquine against chloroquine-resistant Plasmodium falciparum in vitro. | 1986 | Trans. R. Soc. Trop. Med. Hyg. | pmid:3299891 |
| Ose EE and Tonkinson LV | Single-dose treatment of neonatal calf pneumonia with the new macrolide antibiotic tilmicosin. | 1988 | Vet. Rec. | pmid:3195026 |
| Kreuzman AJ et al. | Two distinctive O-methyltransferases catalyzing penultimate and terminal reactions of macrolide antibiotic (tylosin) biosynthesis. Substrate specificity, enzyme inhibition, and kinetic mechanism. | 1988 | J. Biol. Chem. | pmid:3170602 |
| Bauer NJ et al. | Purification, characterization, and kinetic mechanism of S-adenosyl-L-methionine:macrocin O-methyltransferase from Streptomyces fradiae. | 1988 | J. Biol. Chem. | pmid:3170601 |
| Nagaraja TG and Taylor MB | Susceptibility and resistance of ruminal bacteria to antimicrobial feed additives. | 1987 | Appl. Environ. Microbiol. | pmid:3116929 |
| Kaukas A et al. | The effect of ampicillin and tylosin on the faecal enterococci of healthy young chickens. | 1987 | J. Appl. Bacteriol. | pmid:3112089 |
| Huang L et al. | Pharmacokinetic-pharmacodynamic modeling of tylosin against Streptococcus suis in pigs. | 2018 | BMC Vet. Res. | pmid:30355326 |
| Moats WA | Effect of the silica support of bonded reversed-phase columns on chromatography of some antibiotic compounds. | 1986 | J. Chromatogr. | pmid:3023412 |
| Zhu L et al. | Evaluation of the antibacterial activity of tilmicosin-SLN against : in vitro and in vivo studies. | 2018 | Int J Nanomedicine | pmid:30147316 |
| Lemli B et al. | Noncovalent Interaction of Tilmicosin with Bovine Serum Albumin. | 2018 | Molecules | pmid:30065238 |
| De Baere S et al. | In vitro model to assess the adsorption of oral veterinary drugs to mycotoxin binders in a feed- and aflatoxin B1-containing buffered matrix. | 2018 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:30016205 |
| Woolums AR et al. | Multidrug resistant Mannheimia haemolytica isolated from high-risk beef stocker cattle after antimicrobial metaphylaxis and treatment for bovine respiratory disease. | 2018 | Vet. Microbiol. | pmid:29981701 |
| Guo X et al. | Sorption properties of tylosin on four different microplastics. | 2018 | Chemosphere | pmid:29933160 |
| Zhang AJ and Warshaw EM | Pet Consort Dermatitis: The Importance of Asking About Pets. | Dermatitis | pmid:29901502 | |
| Stromer BS et al. | Tylosin sorption to diatomaceous earth described by Langmuir isotherm and Freundlich isotherm models. | 2018 | Chemosphere | pmid:29874766 |
| Müller HC et al. | Effects of intermittent feeding of tylosin phosphate during the finishing period on feedlot performance, carcass characteristics, antimicrobial resistance, and incidence and severity of liver abscesses in steers. | 2018 | J. Anim. Sci. | pmid:29718254 |
| Yin Y et al. | Iron and manganese oxides modified maize straw to remove tylosin from aqueous solutions. | 2018 | Chemosphere | pmid:29689529 |
| Ishikawa NK et al. | Determination of tylosin excretion from sheep to assess tylosin spread to agricultural fields by manure application. | 2018 | Sci. Total Environ. | pmid:29579651 |
| Canning P et al. | Variation in water disappearance, daily dose, and synovial fluid concentrations of tylvalosin and 3-O-acetyltylosin in commerical pigs during five day water medication with tylvalosin under field conditions. | 2018 | J. Vet. Pharmacol. Ther. | pmid:29572923 |
| Dong H et al. | Synthesis and characterization of Ag/BiWO/GO composite for the fast degradation of tylosin under visible light. | 2018 | Environ Sci Pollut Res Int | pmid:29442310 |
| Guo X et al. | Maize straw decorated with sulfide for tylosin removal from the water. | 2018 | Ecotoxicol. Environ. Saf. | pmid:29355772 |
| Patyra E et al. | Development and validation of an LC-MS/MS method for the quantification of tiamulin, trimethoprim, tylosin, sulfadiazine and sulfamethazine in medicated feed. | 2018 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:29324179 |