Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Digital Dermatitis D058066 3 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Elkins CA et al. Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. 2010 Antimicrob. Agents Chemother. pmid:20038628
Granja R et al. Determination of erythromycin and tylosin residues in honey by LC/MS/MS. 2009 May-Jun J AOAC Int pmid:19610392
Sharma R et al. Selected antimicrobial resistance during composting of manure from cattle administered sub-therapeutic antimicrobials. 2009 Mar-Apr J. Environ. Qual. pmid:19202027
Smith GW et al. Elimination kinetics of tilmicosin following intramammary administration in lactating dairy cattle. 2009 J. Am. Vet. Med. Assoc. pmid:19210246
Kouvela EC et al. Distinct mode of interaction of a novel ketolide antibiotic that displays enhanced antimicrobial activity. 2009 Antimicrob. Agents Chemother. pmid:19164155
Baggio A et al. Residues of antibacterial drugs in honey from the Italian market. 2009 Food Addit Contam Part B Surveill pmid:24784967
Chemier JA et al. Trends in microbial synthesis of natural products and biofuels. 2009 Adv. Enzymol. Relat. Areas Mol. Biol. pmid:18990830
Montgomery JL et al. Effects of dietary zilpaterol hydrochloride on feedlot performance and carcass characteristics of beef steers fed with and without monensin and tylosin. 2009 J. Anim. Sci. pmid:18997069
Boles JA et al. Growth implants reduced tenderness of steaks from steers and heifers with different genetic potentials for growth and marbling. 2009 J. Anim. Sci. pmid:18791138
Han C et al. Hydrogenated castor oil nanoparticles as carriers for the subcutaneous administration of tilmicosin: in vitro and in vivo studies. 2009 J. Vet. Pharmacol. Ther. pmid:19290940
Engi H [Perspectives of inhibition of multidrug resistance during cancer chemotherapy, in vitro and in vivo experiments]. 2009 Orv Hetil pmid:19293063
Hoese A et al. Chlortetracycline and tylosin runoff from soils treated with antimicrobial containing manure. 2009 J Environ Sci Health B pmid:19365753
Meyer NF et al. Effect of essential oils, tylosin, and monensin on finishing steer performance, carcass characteristics, liver abscesses, ruminal fermentation, and digestibility. 2009 J. Anim. Sci. pmid:19359504
Christodoulopoulos G Adverse outcome of using tilmicosin in a lamb with multiple ventricular septal defects. 2009 Can. Vet. J. pmid:19337615
Khaliq S et al. Production of tylosin in solid-state fermentation by Streptomyces fradiae NRRL-2702 and its gamma-irradiated mutant (gamma-1). 2009 Lett. Appl. Microbiol. pmid:19780953
Hu D and Coats JR Laboratory evaluation of mobility and sorption for the veterinary antibiotic, tylosin, in agricultural soils. 2009 J Environ Monit pmid:19724833
Khalifeh MS et al. Assessment of humoral and cellular-mediated immune response in chickens treated with tilmicosin, florfenicol, or enrofloxacin at the time of Newcastle disease vaccination. 2009 Poult. Sci. pmid:19762865
Guedes RM et al. Use of tylvalosin-medicated feed to control porcine proliferative enteropathy. 2009 Vet. Rec. pmid:19767637
Fitzgerald J Administration of micotil. 2009 Vet. Rec. pmid:19767643
Stone JJ et al. Effect of antimicrobial compounds tylosin and chlortetracycline during batch anaerobic swine manure digestion. 2009 Water Res. pmid:19695662
Atef M et al. Effect of albendazole administration on pharmacokinetic aspects of tylosin in lactating goats. 2009 Drug Metab Lett pmid:19702546
Hilton GG et al. Effects of feeding zilpaterol hydrochloride with and without monensin and tylosin on carcass cutability and meat palatability of beef steers. 2009 J. Anim. Sci. pmid:19028853
Byrne-Bailey KG et al. Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. 2009 Antimicrob. Agents Chemother. pmid:19064898
Petropoulos AD et al. Time-resolved binding of azithromycin to Escherichia coli ribosomes. 2009 J. Mol. Biol. pmid:19071138
Blackwell PA et al. Effects of agricultural conditions on the leaching behaviour of veterinary antibiotics in soils. 2009 Chemosphere pmid:19128817
Chénier MR and Juteau P Fate of chlortetracycline- and tylosin-resistant bacteria in an aerobic thermophilic sequencing batch reactor treating swine waste. 2009 Microb. Ecol. pmid:19125305
Liu F et al. Effects of six selected antibiotics on plant growth and soil microbial and enzymatic activities. 2009 Environ. Pollut. pmid:19157661
Bodoor K et al. Design and implementation of an ribonucleic acid (RNA) directed fragment library. 2009 J. Med. Chem. pmid:19445516
Hunter RP et al. Letter to the editor. 2009 Br. Poult. Sci. pmid:19904632
Suchodolski JS et al. The effect of the macrolide antibiotic tylosin on microbial diversity in the canine small intestine as demonstrated by massive parallel 16S rRNA gene sequencing. 2009 BMC Microbiol. pmid:19799792
Warner K et al. Control of Ornithobacterium rhinotracheale in poultry. 2009 Vet. Rec. pmid:19946131
Hao H et al. 23S rRNA mutation A2074C conferring high-level macrolide resistance and fitness cost in Campylobacter jejuni. 2009 Microb. Drug Resist. pmid:19857128
Khaliq S et al. Change in colony morphology and kinetics of tylosin production after UV and gamma irradiation mutagenesis of Streptomyces fradiae NRRL-2702. 2009 Microbiol. Res. pmid:17475458
Ramlachan N et al. A comparative study on the effects of tylosin on select bacteria during continuous flow culture of mixed populations of gut microflora derived from a feral and a domestic pig. 2008 Foodborne Pathog. Dis. pmid:18260812
Jacob ME et al. Effects of feeding wet corn distillers grains with solubles with or without monensin and tylosin on the prevalence and antimicrobial susceptibilities of fecal foodborne pathogenic and commensal bacteria in feedlot cattle. 2008 J. Anim. Sci. pmid:18192558
Crespo R and McMillan R Facial cellulitis induced in chickens by Mycoplasma gallisepticum bacterin and its treatment. 2008 Avian Dis. pmid:19166067
Van Donkersgoed J et al. Comparative efficacy of tilmicosin versus tulathromycin as a metaphylactic antimicrobial in feedlot calves at moderate risk for respiratory disease. 2008 Vet. Ther. pmid:19177334
Lilia G et al. Circadian serum concentrations of tylosin in broilers after feed or water medication. 2008 Br. Poult. Sci. pmid:18836909
Cundliffe E Control of tylosin biosynthesis in Streptomyces fradiae. 2008 J. Microbiol. Biotechnol. pmid:18852501
Weber TE and Kerr BJ Effect of sodium butyrate on growth performance and response to lipopolysaccharide in weanling pigs. 2008 J. Anim. Sci. pmid:17998428
Blackwood RS et al. Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta). 2008 Comp. Med. pmid:19793461
Demoling LA and Bååth E No long-term persistence of bacterial pollution-induced community tolerance in tylosin-polluted soil. 2008 Environ. Sci. Technol. pmid:18853809
Castonguay R et al. Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase. 2008 J. Am. Chem. Soc. pmid:18693734
Petropoulos AD et al. Stepwise binding of tylosin and erythromycin to Escherichia coli ribosomes, characterized by kinetic and footprinting analysis. 2008 J. Biol. Chem. pmid:18079110
Akhter S et al. Effect of antibiotics in extender on bacterial and spermatozoal quality of cooled buffalo (Bubalus bubalis) bull semen. 2008 Reprod. Domest. Anim. pmid:18042206
Bailey M et al. Induction of erm(C) expression by noninducing antibiotics. 2008 Antimicrob. Agents Chemother. pmid:18086834
Diagnosis | pasteurellosis. 2008 Lab Anim (NY) pmid:18094697
Wagner BA et al. Effect of antimicrobial dosage regimen on Salmonella and Escherichia coli isolates from feeder swine. 2008 Appl. Environ. Microbiol. pmid:18223115
Kim MH et al. Comparative pharmacokinetics of tylosin or florfenicol after a single intramuscular administration at two different doses of tylosin-florfenicol combination in pigs. 2008 J. Vet. Med. Sci. pmid:18250580
Angenent LT et al. Effect of the presence of the antimicrobial tylosin in swine waste on anaerobic treatment. 2008 Water Res. pmid:18258277