| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Short CR | Comparative pharmacokinetics--sorting the sheep from the goats. | 1999 | Vet. J. | pmid:10558834 |
| Taha AA et al. | Disposition kinetics of tylosin administered intravenously and intramuscularly in desert sheep and Nubian goats. | 1999 | Vet. J. | pmid:10558841 |
| Fodor L et al. | Efficacy evaluations of the use of oral tilmicosin in pneumonic calves. | 2000 | Vet. J. | pmid:10712808 |
| Kilpinen S et al. | Oral tylosin administration is associated with an increase of faecal enterococci and lactic acid bacteria in dogs with tylosin-responsive diarrhoea. | 2015 | Vet. J. | pmid:26049259 |
| Devreese M et al. | Interaction between tylosin and bentonite clay from a pharmacokinetic perspective. | 2012 | Vet. J. | pmid:22749117 |
| Mitchell JD et al. | In vitro pharmacodynamics of gamithromycin against Mycoplasma mycoides subspecies mycoides Small Colony. | 2013 | Vet. J. | pmid:23810743 |
| Wang XF et al. | Enhancement of antibacterial activity of tilmicosin against Staphylococcus aureus by solid lipid nanoparticles in vitro and in vivo. | 2012 | Vet. J. | pmid:21900026 |
| Barbour EK et al. | Impact of synergism of calcium phosphomycin/tylosin tartarate supplements on the performance of broilers in the Lebanon. | 2010 Jan-Mar | Vet. Ital. | pmid:20391366 |
| Nagaraja TG and Lechtenberg KF | Liver abscesses in feedlot cattle. | 2007 | Vet. Clin. North Am. Food Anim. Pract. | pmid:17606156 |
| Hartman EG and Geryl J | Comparison between the minimal inhibitory concentration of tilmicosin and oxytetracycline for bovine pneumonic Pasteurella haemolytica isolates. | 1993 | Vet Q | pmid:8122359 |
| Voeten AC and Litjens JB | The hygienic treatment of turkey eggs by dipping in an antibiotic and disinfectant solution. | 1982 | Vet Q | pmid:7112889 |
| Hopper RJ and Miller ML | Efficacy of swine erysipelas vaccine given simultaneously with medicated rations. | 1981 | Vet Med Small Anim Clin | pmid:6916559 |
| Donev B et al. | [Intramammary drug forms of neotil in treating mastitis during lactation]. | 1982 | Vet Med Nauki | pmid:7157656 |
| Dilov P et al. | [Comparative studies on the resorption, anti-anemic action and growth effect of FV-82 and dextrofer-100 on pigs]. | 1984 | Vet Med Nauki | pmid:6474828 |
| Dilov P et al. | [Toxicity, tolerance and blood concentrations of iron and tylosin with the use of preparation FV-82]. | 1983 | Vet Med Nauki | pmid:6623919 |
| Donev B et al. | [Toxicological studies of a combination of technical tylosin phosphate with bentonite (farmazin TB)]. | 1983 | Vet Med Nauki | pmid:6659350 |
| McGuigan MA | Human exposures to tilmicosin (MICOTIL). | 1994 | Vet Hum Toxicol | pmid:7975134 |
| Jordan WH et al. | A review of the toxicology of the antibiotic MICOTIL 300. | 1993 | Vet Hum Toxicol | pmid:8470360 |
| Gershon P and Howells RE | Synergy of four macrolide antibiotics with chloroquine against chloroquine-resistant Plasmodium falciparum in vitro. | 1986 | Trans. R. Soc. Trop. Med. Hyg. | pmid:3299891 |
| Devreese M et al. | An in vitro model using the IPEC-J2 cell line for efficacy and drug interaction testing of mycotoxin detoxifying agents. | 2013 | Toxicol In Vitro | pmid:23078954 |
| Westermarck E and Wiberg M | Exocrine pancreatic insufficiency in the dog: historical background, diagnosis, and treatment. | 2012 | Top Companion Anim Med | pmid:23148848 |
| Boissevain I | [Punishment after the fact]. | 2007 | Tijdschr Diergeneeskd | pmid:17939495 |
| Westerbeek JA and Jaartsveld FH | [Mycoplasma infection on a cattle farm]. | 1987 | Tijdschr Diergeneeskd | pmid:3603536 |
| Doak GA | Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 2000 | Theriogenology | pmid:10990358 |
| Kim S | Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 2000 | Theriogenology | pmid:10990359 |
| Rosenbusch RF | Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 2000 | Theriogenology | pmid:10990360 |
| Thomas CB | Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 2000 | Theriogenology | pmid:10990361 |
| Visser IJ et al. | Failure of antibiotics gentamycin, tylosin, lincomycin and spectinomycin to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 1999 | Theriogenology | pmid:10728994 |
| Crown LA and Smith RB | Accidental veterinary antibiotic injection into a farm worker. | 1999 | Tenn Med | pmid:10474305 |
| Solliec M et al. | Analysis of trimethoprim, lincomycin, sulfadoxin and tylosin in swine manure using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry. | 2014 | Talanta | pmid:25059125 |
| Chopra S et al. | Characterization of impurities in tylosin using dual liquid chromatography combined with ion trap mass spectrometry. | 2013 | Talanta | pmid:23598092 |
| Dinh QT et al. | Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. | 2011 | Talanta | pmid:21807177 |
| Fang XM et al. | [A study on space mutation of Streptomyces fradiae]. | 2005 | Space Med Med Eng (Beijing) | pmid:15977391 |
| Horie M et al. | [Determination of spiramycin and tilmicosin in meat and fish by LC/MS]. | 2003 | Shokuhin Eiseigaku Zasshi | pmid:12968469 |
| Xie W et al. | [Determination of five macrolide antibiotic residues in royal jelly samples by using high performance liquid chromatography tandem mass spectrometry]. | 2007 | Se Pu | pmid:17679440 |
| Avci T and Elmas M | Milk and blood pharmacokinetics of tylosin and tilmicosin following parenteral administrations to cows. | 2014 | ScientificWorldJournal | pmid:25177733 |
| Sura S et al. | Transport of three veterinary antimicrobials from feedlot pens via simulated rainfall runoff. | 2015 | Sci. Total Environ. | pmid:25839178 |
| Luby EM et al. | Fate and transport of tylosin-resistant bacteria and macrolide resistance genes in artificially drained agricultural fields receiving swine manure. | 2016 | Sci. Total Environ. | pmid:26874610 |
| Li Q et al. | Co-addition of manure increases the dissipation rates of tylosin A and the numbers of resistance genes in laboratory incubation experiments. | 2015 | Sci. Total Environ. | pmid:25958362 |
| Ishikawa NK et al. | Determination of tylosin excretion from sheep to assess tylosin spread to agricultural fields by manure application. | 2018 | Sci. Total Environ. | pmid:29579651 |
| Washington MT et al. | Monitoring tylosin and sulfamethazine in a tile-drained agricultural watershed using polar organic chemical integrative sampler (POCIS). | 2018 | Sci. Total Environ. | pmid:28854391 |
| Srinivasan P et al. | Sorption of selected veterinary antibiotics onto dairy farming soils of contrasting nature. | 2014 | Sci. Total Environ. | pmid:24326064 |
| Xia X et al. | Proteomic analysis of tylosin-resistant Mycoplasma gallisepticum reveals enzymatic activities associated with resistance. | 2015 | Sci Rep | pmid:26584633 |
| Brown K et al. | Antimicrobial growth promoters modulate host responses in mice with a defined intestinal microbiota. | 2016 | Sci Rep | pmid:27929072 |
| Huwyler U et al. | Efficacy evaluation of the use of oral tilmicosin in pneumonic calves. | 1999 | Schweiz. Arch. Tierheilkd. | pmid:10228400 |
| Greer RT and Ryoo JP | Development of ocular inserts for cattle. | 1987 | Scanning Microsc. | pmid:3616580 |
| Reynaldi FJ et al. | [Binding of tylosin, tilmicosin and oxytetracycline to proteins from honeybees, larvae and beehive products]. | 2010 Oct-Dec | Rev. Argent. Microbiol. | pmid:21229198 |
| Timsit E et al. | Effects of nasal instillation of a nitric oxide-releasing solution or parenteral administration of tilmicosin on the nasopharyngeal microbiota of beef feedlot cattle at high-risk of developing respiratory tract disease. | 2017 | Res. Vet. Sci. | pmid:28231472 |
| Allan EM and Pirie HM | In vitro activity of tiamulin against bovine respiratory tract mycoplasmas. | 1981 | Res. Vet. Sci. | pmid:7323463 |
| Prats C et al. | Disposition kinetics of tylosin administered intravenously and intramuscularly to pigs. | 2002 | Res. Vet. Sci. | pmid:12204632 |