Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Appl. Environ. Microbiol. (2)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Moore GM et al. | Efficacy dose determination study of tilmicosin phosphate in feed for control of pneumonia caused by Actinobacillus pleuropneumoniae in swine. | 1996 | Am. J. Vet. Res. | pmid:8633812 |
| Moore GM et al. | Clinical field trials with tilmicosin phosphate in feed for the control of naturally acquired pneumonia caused by Actinobacillus pleuropneumoniae and Pasteurella multocida in swine. | 1996 | Am. J. Vet. Res. | pmid:8633813 |
| Day FG | The value of tilmicosin in production medicine. | 1996 | J. Am. Vet. Med. Assoc. | pmid:8617615 |
| Solenberg PJ et al. | Transposition mutagenesis in Streptomyces fradiae: identification of a neutral site for the stable insertion of DNA by transposon exchange. | 1996 | Gene | pmid:8626067 |
| Arisawa A et al. | Direct fermentative production of acyltylosins by genetically-engineered strains of Streptomyces fradiae. | 1996 | J. Antibiot. | pmid:8641997 |
| Musser J et al. | Comparison of tilmicosin with long-acting oxytetracycline for treatment of respiratory tract disease in calves. | 1996 | J. Am. Vet. Med. Assoc. | pmid:8682696 |
| Katoh T et al. | The fractional inhibitory concentration index of antimicrobial agents for bacteria and Mycoplasma isolated from the nasal swabs of cattle with respiratory diseases. | 1996 | J. Vet. Med. Sci. | pmid:8877979 |
| Katoh T et al. | Effect of a combination of antimicrobial agents for the treatment of respiratory disease in cattle. | 1996 | J. Vet. Med. Sci. | pmid:8877980 |
| McKay SG et al. | Use of tilmicosin for treatment of pasteurellosis in rabbits. | 1996 | Am. J. Vet. Res. | pmid:8836371 |
| Shryock TR et al. | Minimum inhibitory concentration breakpoints and disk diffusion inhibitory zone interpretive criteria for tilmicosin susceptibility testing against Pasteurella spp. associated with bovine respiratory disease. | 1996 | J. Vet. Diagn. Invest. | pmid:8844577 |
| Scott DW et al. | Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. | 1996 | Can. Vet. J. | pmid:8896878 |
| Harvey RG | Tylosin in the treatment of canine superficial pyoderma. | 1996 | Vet. Rec. | pmid:8873399 |
| Kobayashi H et al. | Macrolide susceptibility of Mycoplasma hyorhinis isolated from piglets. | 1996 | Antimicrob. Agents Chemother. | pmid:8849222 |
| Gandecha AR and Cundliffe E | Molecular analysis of tlrD, an MLS resistance determinant from the tylosin producer, Streptomyces fradiae. | 1996 | Gene | pmid:8973363 |
| Kobayashi H et al. | In vitro susceptibility of Mycoplasma hyosynoviae and M. hyorhinis to antimicrobial agents. | 1996 | J. Vet. Med. Sci. | pmid:8959659 |
| Kuhstoss S et al. | Production of a novel polyketide through the construction of a hybrid polyketide synthase. | 1996 | Gene | pmid:8996112 |
| Jordan FT and Horrocks BK | The minimum inhibitory concentration of tilmicosin and tylosin for mycoplasma gallisepticum and Mycoplasma synoviae and a comparison of their efficacy in the control of Mycoplasma gallisepticum infection in broiler chicks. | 1996 Apr-Jun | Avian Dis. | pmid:8790882 |
| Houglum JE and Tasler MK | Liquid chromatographic assay of tylosin in animal feeds. | 1996 Mar-Apr | J AOAC Int | pmid:8920123 |
| Delépine B et al. | Multiresidue method for confirmation of macrolide antibiotics in bovine muscle by liquid chromatography/mass spectrometry. | 1996 Mar-Apr | J AOAC Int | pmid:8920126 |
| Ngoh MA | Determination of tilmicosin in bovine milk by liquid chromatography with ultraviolet detection. | 1996 May-Jun | J AOAC Int | pmid:8634534 |