Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Conjunctivitis, Viral D003236 1 associated lipids
Enterotoxemia D004767 1 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Primate Diseases D018419 2 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Digital Dermatitis D058066 3 associated lipids
Tracheal Diseases D014133 3 associated lipids
Treponemal Infections D014211 3 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Dysentery D004403 4 associated lipids
Mycotoxicosis D015651 5 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Foreign Bodies D005547 5 associated lipids
Pyoderma D011711 5 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Delepine B et al. Identification of tylosin in bovine muscle at the maximum residue limit level by liquid chromatography-mass spectrometry, using a particle beam interface. 1994 Analyst pmid:7879883
Ammida NH et al. Analysis of erythromycin and tylosin in bovine muscle using disposable screen printed electrodes. 2004 Analyst pmid:14737577
Martínez MF and Barth AD Early detection and treatment of vesicular adenitis in bulls. 2007 Anim. Reprod. Sci. pmid:17027202
Kawai K et al. Antimicrobial susceptibilities of Mycoplasma isolated from bovine mastitis in Japan. 2014 Anim. Sci. J. pmid:24261609
Berque I et al. [Stereoselective synthesis of biologically active macrolides. Total synthesis of tylosine]. 1998 Ann Pharm Fr pmid:9770007
Pai MP et al. Macrolide drug interactions: an update. 2000 Ann Pharmacother pmid:10772438
Mironov VA et al. [Effect of Ca2+ ions on biosynthesis and component composition of tylosin in Streptomyces fradiae]. 1997 Antibiot. Khimioter. pmid:9182505
Navashin SM et al. [Genetic and biochemical control of biosynthesis of macrolide antibiotics]. 1990 Antibiot. Khimioter. pmid:2078074
Tikhomirova LA et al. [Cytomorphological and cultural characteristics of tylosin-producing strains with different antibiotic activity]. 1991 Antibiot. Khimioter. pmid:1755702
MiliavskiÄ­ EB et al. [Electrophoretic separation of spores of producers of kanamycin and tylosin]. 1990 Antibiot. Khimioter. pmid:2334246
Panfilova ZI et al. [Obtaining of mutants of Streptomyces fradiae producing tylosin by action of nitrosomethylurea on synchronously germinating spores]. 1990 Antibiot. Khimioter. pmid:2383150
Esipov SE [Novel mathematical approach to determination of antibiotics concentration by agar diffusion method. Analysis of graphical, table and mathematical options of relative biological activity estimation]. 1998 Antibiot. Khimioter. pmid:9606490
Malanicheva IA et al. [Protoplast fusion in Streptomyces fradiae strains producing neomycin and tylosin]. 1992 Antibiot. Khimioter. pmid:1296531
Rodionova II et al. [Effect of protoplast formation on the antibiotic activity of the Streptomyces fradiae 165 strain--a producer of tylosin]. 1987 Antibiot. Med. Biotekhnol. pmid:2830838
Smith LK and Mankin AS Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. 2008 Antimicrob. Agents Chemother. pmid:18299405
Ayling RD et al. Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection. 2005 Antimicrob. Agents Chemother. pmid:16304194
Chin AC et al. Tilmicosin induces apoptosis in bovine peripheral neutrophils in the presence or in the absence of Pasteurella haemolytica and promotes neutrophil phagocytosis by macrophages. 2000 Antimicrob. Agents Chemother. pmid:10952596
Jost BH et al. Tylosin resistance in Arcanobacterium pyogenes is encoded by an erm X determinant. 2003 Antimicrob. Agents Chemother. pmid:14576111
Elkins CA and Mullis LB Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. 2007 Antimicrob. Agents Chemother. pmid:17210767
Chin NX and Neu HC In vitro activity of MC-352, a new 16-membered macrolide. 1992 Antimicrob. Agents Chemother. pmid:1416853