Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Prats C et al. | Tylosin depletion from edible pig tissues. | 2002 | Res. Vet. Sci. | pmid:12443694 |
Cooper AC et al. | In vitro activity of danofloxacin, tylosin and oxytetracycline against mycoplasmas of veterinary importance. | 1993 | Res. Vet. Sci. | pmid:8393208 |
Cester CC et al. | Effect of stage of oestrous cycle on tylosin disposition in genital tract secretions of cows. | 1993 | Res. Vet. Sci. | pmid:8434145 |
Crepieux T et al. | Randomized, non-inferiority trial comparing a nitric oxide releasing solution with a macrolide antibiotic for control of bovine respiratory disease in beef feedlot calves at high-risk of developing respiratory tract disease. | 2016 | Res. Vet. Sci. | pmid:27033936 |
El-Ela FI et al. | Investigating the potential role of vitamin E in modulating the immunosuppressive effects of tylvalosin and florfenicol in broiler chickens. | 2016 | Res. Vet. Sci. | pmid:27663366 |
Ramadan A | Pharmacokinetics of tilmicosin in serum and milk of goats. | 1997 Jan-Feb | Res. Vet. Sci. | pmid:9160424 |
Pringle M et al. | Tiamulin resistance in porcine Brachyspira pilosicoli isolates. | 2006 | Res. Vet. Sci. | pmid:16253666 |
Gourlay RN et al. | Effect of a new macrolide antibiotic (tilmicosin) on pneumonia experimentally induced in calves by Mycoplasma bovis and Pasteurella haemolytica. | 1989 | Res. Vet. Sci. | pmid:2772410 |
Goodwin RF | In vitro activity of tiamulin against porcine mycoplasmas. | 1985 | Res. Vet. Sci. | pmid:3975477 |
Prats C et al. | Disposition kinetics of tylosin administered intravenously and intramuscularly to pigs. | 2002 | Res. Vet. Sci. | pmid:12204632 |