Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Goodwin RF | In vitro activity of tiamulin against porcine mycoplasmas. | 1985 | Res. Vet. Sci. | pmid:3975477 |
Potter EL et al. | Effect of monensin and tylosin on average daily gain, feed efficiency and liver abscess incidence in feedlot cattle. | 1985 | J. Anim. Sci. | pmid:4077750 |
Stipkovits L et al. | Efficacy of lasalocid sodium against mycoplasmas (preliminary communication). | 1984 | Acta Vet. Hung. | pmid:6242271 |
Omura S et al. | Ammonium ions suppress the amino acid metabolism involved in the biosynthesis of protylonolide in a mutant of Streptomyces fradiae. | 1984 | J. Antibiot. | pmid:6511663 |
Stipkovits L et al. | A comparison of the effect of tiamulin hydrogen fumarate and tylosin tartrate on mycoplasmas of ruminants and some animal ureaplasmas. | 1984 | Vet. Microbiol. | pmid:6730305 |
Dotzlaf JE et al. | Incorporation of amino acid-derived carbon into tylactone by Streptomyces fradiae GS14. | 1984 | Antimicrob. Agents Chemother. | pmid:6424562 |
Mackinnon JD et al. | Effect of tylosin on milk yield and dry matter intake of lactating dairy cows. | 1984 | Vet. Rec. | pmid:6495581 |
Omura S et al. | Chemical modification of tylosin. Thioether derivatives of tylosin and demycarosyltylosin. | 1984 | J. Antibiot. | pmid:6501102 |
Dafwang II et al. | Broiler chick growth response to antibiotics, 1981-1982. | 1984 | Poult. Sci. | pmid:6610176 |
Omura S et al. | Effect of ammonium ion, inorganic phosphate and amino acids on the biosynthesis of protylonolide, a precursor of tylosin aglycone. | 1984 | J. Antibiot. | pmid:6735923 |